Twins vs Giants Prediction, Odds, Moneyline, Spread & Over/Under for May 11

Odds updated as of 1:12 a.m.

The Sunday schedule in MLB includes a matchup between the Minnesota Twins and the San Francisco Giants.

Before checking out the MLB betting lines on FanDuel Sportsbook, we've got you covered, in terms of the vital info about this matchup.

Twins vs Giants Game Info

• Minnesota Twins (20-20) vs. San Francisco Giants (24-16)
• Date: Sunday, May 11, 2025
• Time: 2:10 p.m. ET
• Venue: Target Field -- Minneapolis, Minnesota
• Coverage: MNNT and NBCS-BA

Twins vs Giants Odds & Moneyline

• All MLB odds, betting lines and prop bets are available on FanDuel Sportsbook.
• Moneyline: MIN: (-146) | SF: (+124)
• Spread: MIN: -1.5 (+134) | SF: +1.5 (-162)
• Total: 8 -- Over: (-115) | Under: (-105)

Twins vs Giants Probable Starting Pitchers

Probable Pitchers: Pablo Lopez (Twins) - 3-2, 2.18 ERA vs Landen Roupp (Giants) - 2-3, 4.89 ERA

The Twins will give the ball to Pablo Lopez (3-2, 2.18 ERA), who is eyeing win No. 4 on the season, and the Giants will counter with Landen Roupp (2-3, 4.89 ERA). When Lopez starts, his team is 4-2-0 against the spread this season. Lopez's team has won 60% of his starts when they are favored on the moneyline (3-2). The Giants have gone 2-5-0 against the spread when Roupp starts. The Giants are 2-2 in Roupp's four starts this season that they were the underdog on the moneyline.

Twins vs Giants Prediction & Pick

All MLB win probability predictions and picks are according to numberFire.
Prediction: Twins win (55.2%)

Twins vs Giants Moneyline

• San Francisco is the underdog, +124 on the moneyline, while Minnesota is a -146 favorite at home.

Twins vs Giants Spread

• The Giants are at the Twins, and are +1.5 on the runline. The Giants are +134 to cover the spread, and the Twins are -162.

Twins vs Giants Over/Under

• An over/under of 8 has been set for Twins-Giants on May 11, with the over being -115 and the under -105.

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Twins vs Giants Betting Trends

• The Twins have been favorites in 26 games this season and have come away with the win 14 times (53.8%) in those contests.
• This season Minnesota has been victorious eight times in 11 chances when named as a favorite of at least -146 on the moneyline.
• The Twins and their opponents have gone over in 13 of their 39 games with a total set by sportsbooks this season.
• The Twins are 21-18-0 against the spread in their 39 games that had a posted line this season.
• The Giants have been the underdog on the moneyline 15 total times this season. They've finished 8-7 in those games.
• San Francisco is 4-3 (winning 57.1% of its games) when playing as a moneyline underdog of +124 or longer.
• The Giants have had an over/under set by oddsmakers 40 times, and have combined with opponents to go over the total in 22 of those games (22-17-1).
• The Giants have covered 47.5% of their games this season, going 19-21-0 against the spread.

Twins Player Leaders

• Byron Buxton leads Minnesota with 39 hits and a team-best slugging percentage of .535. He's batting .271 with an on-base percentage of .314.
• Among all qualified hitters in MLB, he ranks 53rd in batting average, 97th in on-base percentage, and 15th in slugging.
• Ty France leads the Twins with an OPS of .722. He has a slash line of .269/.335/.386 this season.
• Among qualifying batters, his batting average places him 55th, his on-base percentage 74th, and his slugging percentage 103rd.
• Trevor Larnach is batting .232 with a .380 slugging percentage and 20 RBI this year.
• Larnach has recorded a hit in three games in a row. During his last five outings he is batting .250 with a double, two home runs and four RBIs.
• Harrison Bader is batting .290 with a .383 OBP and 16 RBI for Minnesota this season.
• Bader enters this matchup on a two-game hitting streak. During his last five outings he is hitting .400 with two doubles, a home run, four walks and three RBIs.

Giants Player Leaders

• Jung Hoo Lee has 43 hits with a .467 slugging percentage, both team-high stats for the Giants. He's batting .287 and with an on-base percentage of .337.
• He is 34th in batting average, 70th in on-base percentage and 46th in slugging percentage among all qualified hitters in the majors.
• Matt Chapman has five doubles, eight home runs and 29 walks while hitting .217. He's slugging .428 with an on-base percentage of .353.
• He is currently 133rd in batting average, 49th in on-base percentage and 66th in slugging percentage among all qualified hitters.
• Wilmer Flores has two doubles, seven home runs and nine walks while batting .245.
• Heliot Ramos is hitting .268 with 10 doubles, six home runs and 12 walks.

Twins vs Giants Head to Head

• 5/10/2025: 2-1 MIN (Favorite: Giants, Spread: -1.5, Total: 7, Favorite Moneyline: -116, Underdog Moneyline: -102)
• 5/9/2025: 3-1 MIN (Favorite: Giants, Spread: -1.5, Total: 8.5, Favorite Moneyline: -116, Underdog Moneyline: -102)
• 7/14/2024: 3-2 SF (Favorite: Giants, Spread: -1.5, Total: 7.5, Favorite Moneyline: -156, Underdog Moneyline: +132)
• 7/13/2024: 4-2 MIN (Favorite: Giants, Spread: -1.5, Total: 8, Favorite Moneyline: -132, Underdog Moneyline: +112)
• 7/12/2024: 7-1 SF (Favorite: Twins, Spread: -1.5, Total: 7.5, Favorite Moneyline: -142, Underdog Moneyline: +120)
• 5/24/2023: 7-1 MIN (Favorite: Twins, Spread: -1.5, Total: 7.5, Favorite Moneyline: -152, Underdog Moneyline: +128)
• 5/23/2023: 4-3 SF (Favorite: Twins, Spread: -1.5, Total: 8, Favorite Moneyline: -146, Underdog Moneyline: +124)
• 5/22/2023: 4-1 SF (Favorite: Twins, Spread: -1.5, Total: 8.5, Favorite Moneyline: -164, Underdog Moneyline: +138)
• 8/28/2022: 8-3 MIN (Favorite: Twins, Spread: -1.5, Total: 8.5, Favorite Moneyline: -110, Underdog Moneyline: -106)
• 8/27/2022: 3-2 MIN (Favorite: Twins, Spread: -1.5, Total: 7.5, Favorite Moneyline: -138, Underdog Moneyline: +118)

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