Twins vs Astros Prediction, Odds, Moneyline, Spread & Over/Under for April 5

Odds updated as of 2:11 p.m.

MLB action on Saturday includes the Minnesota Twins taking on the Houston Astros.

Here's what you need to know before checking out today's MLB odds and spreads on FanDuel Sportsbook.

Twins vs Astros Game Info

• Minnesota Twins (2-5) vs. Houston Astros (3-4)
• Date: Saturday, April 5, 2025
• Time: 2:10 p.m. ET
• Venue: Target Field -- Minneapolis, Minnesota
• Coverage: MNNT and SCHN

Twins vs Astros Odds & Moneyline

• All MLB odds, betting lines and prop bets are available on FanDuel Sportsbook.
• Moneyline: MIN: (-130) | HOU: (+110)
• Spread: MIN: -1.5 (+164) | HOU: +1.5 (-200)
• Total: 7.5 -- Over: (-118) | Under: (-104)

Twins vs Astros Probable Starting Pitchers

Probable Pitchers: Bailey Ober (Twins) - 0-1, 27.00 ERA vs Spencer Arrighetti (Astros) - 1-0, 1.50 ERA

The Twins will give the nod to Bailey Ober (0-1, 27.00 ERA), who is eyeing win No. 1 on the season, and the Astros will counter with Spencer Arrighetti (1-0, 1.50 ERA). Ober and his team failed to cover the spread in his only opportunity this season as a starter. Ober's team lost his only start as a favorite this season. Arrighetti has started only one game with a set spread, which the Astros failed to cover. The Astros have yet to be named a moneyline underdog when Arrighetti starts this season.

Twins vs Astros Prediction & Pick

All MLB win probability predictions and picks are according to numberFire.
Prediction: Astros win (52.2%)

Twins vs Astros Moneyline

• Houston is a +110 underdog on the moneyline, while Minnesota is a -130 favorite at home.

Twins vs Astros Spread

• The Astros are at the Twins, and are +1.5 on the runline. The Astros are +164 to cover the spread, and the Twins are -200.

Twins vs Astros Over/Under

• An over/under of 7.5 has been set for Twins-Astros on April 5, with the over being -118 and the under -104.

Bet on Minnesota Twins vs. Houston Astros on FanDuel today!

Twins vs Astros Betting Trends

• The Twins have come away with two wins in the seven contests they have been listed as the favorites in this season.
• Minnesota has a record of 2-2 in contests when bookmakers favor them by -130 or more on the moneyline.
• The Twins and their opponents have gone over in four of their seven games with a total set by sportsbooks this season.
• The Twins are 2-5-0 against the spread in their seven games that had a posted line this season.
• The Astros have been the moneyline underdog only two other times so far this season, and they split the games.
• Houston has played as a moneyline underdog of +110 or longer in only two games this season, which it split 1-1.
• The Astros have played in seven games with a set over/under, and have combined with opponents to go over the total two times (2-4-1).
• The Astros have a 2-5-0 record against the spread this season (covering just 28.6% of the time).

Twins Player Leaders

• Harrison Bader is batting .211 with a double and three home runs. He has an on-base percentage of .211 and a slugging percentage of .737.
• Willi Castro leads Minnesota with six hits and an OBP of .346, plus a team-best slugging percentage of .522. He's batting .261.
• Among all qualified, he is 71st in batting average, 70th in on-base percentage and 48th in slugging percentage.
• Byron Buxton has an OPS of .669, fueled by an OBP of .269 and a team-best slugging percentage of .400 this season.
• Buxton brings a three-game hitting streak into this matchup. In his last five games he is hitting .353 with a double, a home run, a walk and three RBI.
• Ty France is batting .192 with a .250 OBP and two RBI for Minnesota this season.

Astros Player Leaders

• Jeremy Pena is hitting .130 with two home runs and two walks. He's slugging .391 with an on-base percentage of .231.
• Including all qualified hitters, he ranks 168th in batting average, while his on-base percentage ranks 162nd and he is 92nd in slugging.
• Jose Altuve has racked up nine hits with a .367 on-base percentage while slugging .429. Those stats are all team-highs. He also has a batting average of .321.
• Including all qualified hitters, he is 28th in batting average, 56th in on-base percentage and 85th in slugging percentage.
• Brendan Rodgers has a double and two walks while hitting .313.
• Isaac Paredes is hitting .130 with a double and five walks.

Twins vs Astros Head to Head

• 4/3/2025: 5-2 HOU (Favorite: Twins, Spread: -1.5, Total: 7, Favorite Moneyline: -138, Underdog Moneyline: +118)
• 7/7/2024: 3-2 MIN (Favorite: Twins, Spread: -1.5, Total: 8.5, Favorite Moneyline: -148, Underdog Moneyline: +126)
• 7/6/2024: 9-3 MIN (Favorite: Twins, Spread: -1.5, Total: 7.5, Favorite Moneyline: -138, Underdog Moneyline: +118)
• 7/5/2024: 13-12 HOU (Favorite: Twins, Spread: -1.5, Total: 8, Favorite Moneyline: -154, Underdog Moneyline: +130)
• 6/2/2024: 4-3 MIN (Favorite: Astros, Spread: -1.5, Total: 8, Favorite Moneyline: -148, Underdog Moneyline: +126)
• 6/1/2024: 5-2 HOU (Favorite: Astros, Spread: -1.5, Total: 7.5, Favorite Moneyline: -118, Underdog Moneyline: -100)
• 5/31/2024: 6-1 MIN (Favorite: Astros, Spread: -1.5, Total: 8, Favorite Moneyline: -110, Underdog Moneyline: -106)
• 10/11/2023: 3-2 HOU (Favorite: Twins, Spread: -1.5, Total: 8.5, Favorite Moneyline: -130, Underdog Moneyline: +110)
• 10/10/2023: 9-1 HOU (Favorite: Twins, Spread: -1.5, Total: 8, Favorite Moneyline: -134, Underdog Moneyline: +114)
• 10/8/2023: 6-2 MIN (Favorite: Astros, Spread: -1.5, Total: 7.5, Favorite Moneyline: -134, Underdog Moneyline: +114)

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