Tigers vs Padres Prediction, Odds, Moneyline, Spread & Over/Under for March 28

Odds updated as of 5:12 a.m.

The Detroit Tigers will take on the San Diego Padres in MLB action on Saturday.

Here's everything you need to know before checking out today's MLB odds and spreads on FanDuel Sportsbook.

Tigers vs Padres Game Info

• Detroit Tigers (2-0) vs. San Diego Padres (0-2)
• Date: Saturday, March 28, 2026
• Time: 8:40 p.m. ET
• Venue: Petco Park -- San Diego, California
• Coverage: Padres.TV and DSN

Tigers vs Padres Odds & Moneyline

• All MLB odds, betting lines and prop bets are available on FanDuel Sportsbook.
• Moneyline: DET: (-116) | SD: (-102)
• Spread: DET: -1.5 (+140) | SD: +1.5 (-170)
• Total: 8 -- Over: (-108) | Under: (-112)

Tigers vs Padres Probable Starting Pitchers

Probable Pitchers: Jack Flaherty (Tigers) - 0-0, 0.00 ERA vs Randy Vasquez (Padres) - 0-0, 0.00 ERA

The Tigers will give the nod to Jack Flaherty against the Padres and Randy Vasquez. Flaherty and his team were 11-22-0 ATS in his 33 appearances with a spread last season. Flaherty and his team were 7-13 when he pitched and they were the moneyline favorite. Last season Vasquez and his team had a 15-11-0 record against the spread in games he pitched. Vasquez and his team had a 10-8 record in games he pitched when they were moneyline underdogs a season ago.

Tigers vs Padres Prediction & Pick

All MLB win probability predictions and picks are according to numberFire.
Prediction: Tigers win (50.3%)

Tigers vs Padres Moneyline

• Detroit is the favorite, -116 on the moneyline, while San Diego is a -102 underdog despite being at home.

Tigers vs Padres Spread

• The Padres are hosting the Tigers, and are +1.5 on the runline. The Padres are +140 to cover the spread, and the Tigers are -170.

Tigers vs Padres Over/Under

• A total of 8 runs has been set for the Tigers-Padres contest on March 28, with the over available at -108 and the under at -112.

Bet on Detroit Tigers vs. San Diego Padres on FanDuel today!

Tigers vs Padres Betting Trends

• The Tigers came away with 59 wins in the 108 contests they were listed as the favorites last season.
• Last year, Detroit won 57 of 103 games when listed as at least -116 on the moneyline.
• The Tigers and their opponents hit the over in 80 of their 162 games with a total last season.
• The Padres were the moneyline underdog 70 times last season. They went 34-36 in those games.
• San Diego went 30-34 when playing as a moneyline underdog with odds of -102 or longer (46.9%).
• The Padres combined with their opponents to go over the total 70 times last season for a 70-90-3 record against the over/under.

Tigers Player Leaders

• Gleyber Torres ended last season with an OBP of .358 while batting .256 with 85 walks and 79 runs scored.
• Riley Greene finished with 155 hits and a slugging percentage of .493.
• Last season, Spencer Torkelson finished with 31 home runs, 78 RBI and a batting average of .240 last season.
• Zach McKinstry slashed .259/.333/.438 and finished with an OPS of .771.

Padres Player Leaders

• Fernando Tatis Jr. had a .368 on-base percentage while batting .268 last season.
• Manny Machado recorded 169 hits and slugged .460.
• Ramon Laureano had 26 doubles, two triples, 24 home runs and 35 walks while hitting .281 last season.
• Xander Bogaerts hit .263 with 30 doubles, 11 home runs and 48 walks.

Tigers vs Padres Head to Head

• 3/27/2026: 5-2 DET (Favorite: Padres, Spread: -1.5, Total: 7.5, Favorite Moneyline: -132, Underdog Moneyline: +112)
• 3/26/2026: 8-2 DET (Favorite: Tigers, Spread: -1.5, Total: 7, Favorite Moneyline: -126, Underdog Moneyline: +108)
• 4/23/2025: 6-0 DET (Favorite: Tigers, Spread: -1.5, Total: 8.5, Favorite Moneyline: -162, Underdog Moneyline: +136)
• 4/22/2025: 2-0 SD (Favorite: Tigers, Spread: -1.5, Total: 7.5, Favorite Moneyline: -134, Underdog Moneyline: +114)
• 4/21/2025: 6-4 DET (Favorite: Tigers, Spread: -1.5, Total: 8.5, Favorite Moneyline: -142, Underdog Moneyline: +120)
• 9/5/2024: 4-3 DET (Favorite: Padres, Spread: -1.5, Total: 8, Favorite Moneyline: -158, Underdog Moneyline: +134)
• 9/4/2024: 6-5 SD (Favorite: Padres, Spread: -1.5, Total: 7.5, Favorite Moneyline: -190, Underdog Moneyline: +160)
• 9/2/2024: 3-0 SD (Favorite: Padres, Spread: -1.5, Total: 8, Favorite Moneyline: -198, Underdog Moneyline: +166)
• 7/23/2023: 3-1 DET (Favorite: Padres, Spread: -1.5, Total: 8.5, Favorite Moneyline: -210, Underdog Moneyline: +176)
• 7/22/2023: 14-3 SD (Favorite: Padres, Spread: -1.5, Total: 10, Favorite Moneyline: -138, Underdog Moneyline: +118)

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