Tigers vs Cubs Prediction, Odds, Moneyline, Spread & Over/Under for June 6

Odds updated as of 5:12 p.m.

The MLB's Friday slate includes the Detroit Tigers taking on the Chicago Cubs.

We've got you covered, in terms of the most important info about this matchup before you take a look at the MLB odds and spreads on FanDuel Sportsbook.

Tigers vs Cubs Game Info

• Detroit Tigers (41-23) vs. Chicago Cubs (39-23)
• Date: Friday, June 6, 2025
• Time: 7:10 p.m. ET
• Venue: Comerica Park -- Detroit, Michigan
• Coverage: Apple TV+

Tigers vs Cubs Odds & Moneyline

• All MLB odds, betting lines and prop bets are available on FanDuel Sportsbook.
• Moneyline: DET: (-198) | CHC: (+166)
• Spread: DET: -1.5 (+114) | CHC: +1.5 (-137)
• Total: 7 -- Over: (-108) | Under: (-112)

Tigers vs Cubs Probable Starting Pitchers

Probable Pitchers: Tarik Skubal (Tigers) - 5-2, 2.26 ERA vs Ben Brown (Cubs) - 3-3, 5.72 ERA

The Tigers will give the nod to Tarik Skubal (5-2, 2.26 ERA), who is eyeing win No. 6 on the season, and the Cubs will turn to Ben Brown (3-3, 5.72 ERA). When Skubal starts, his team is 6-6-0 against the spread this season. Skubal's team is 8-3 this season when he starts and they are the moneyline favorite. The Cubs have a 5-5-0 record against the spread in Brown's starts. The Cubs were the moneyline underdog for two Brown starts this season -- they split the games.

Tigers vs Cubs Prediction & Pick

All MLB win probability predictions and picks are according to numberFire.
Prediction: Tigers win (52.9%)

Tigers vs Cubs Moneyline

• Chicago is the underdog, +166 on the moneyline, while Detroit is a -198 favorite at home.

Tigers vs Cubs Spread

• The Tigers are hosting the Cubs and are favored by 1.5 runs (+114 to cover) on the runline. Chicago is -137 to cover.

Tigers vs Cubs Over/Under

• Tigers versus Cubs, on June 6, has an over/under of 7, with the over being -108 and the under -112.

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Tigers vs Cubs Betting Trends

• The Tigers have been favorites in 39 games this season and have come away with the win 26 times (66.7%) in those contests.
• Detroit has a record of 7-2 in contests when sportsbooks favor them by -198 or more on the moneyline.
• The Tigers and their opponents have gone over in 29 of their 62 games with a total set by sportsbooks this season.
• The Tigers have posted a record of 34-28-0 against the spread this season.
• The Cubs have won 47.4% of the games this season they were the moneyline underdog (9-10).
• Chicago has played as a moneyline underdog of +166 or longer in only one game this season, which it won.
• In the 60 games oddsmakers have set an over/under for the Cubs, they have combined with opponents to go over the total 35 times (35-22-3).
• The Cubs have gone 32-28-0 against the spread this season.

Tigers Player Leaders

• Spencer Torkelson is hitting .227 with 14 doubles, 14 home runs and 33 walks. He has an on-base percentage of .339 while slugging .486.
• Among all qualifying hitters in the majors, he ranks 136th in batting average, 64th in on-base percentage, and 36th in slugging.
• Gleyber Torres leads Detroit in OBP (.379) this season, fueled by 48 hits. He's batting .264 while slugging .396.
• His batting average ranks 69th among qualified players, his on-base percentage 22nd, and his slugging percentage 109th.
• Riley Greene has an OPS of .839, fueled by an OBP of .335 and a team-best slugging percentage of .504 this season.
• Kerry Carpenter has 57 hits, which ranks first among Detroit hitters this season, while batting .273 with 22 extra-base hits.

Cubs Player Leaders

• Kyle Tucker has an on-base percentage of .395, a team-best for the Cubs. He's batting .283 and slugging .522.
• Including all qualifying hitters in the majors, his batting average places him 30th, his on-base percentage ranks 10th, and he is 15th in slugging.
• Pete Crow-Armstrong's 67 hits and .557 slugging percentage both lead his team. He has a batting average of .275 with an on-base percentage of .312.
• He is currently 43rd in batting average, 108th in on-base percentage and eighth in slugging percentage among all qualifying hitters.
• Seiya Suzuki is hitting .270 with 18 doubles, two triples, 14 home runs and 25 walks.
• Nico Hoerner's .368 slugging percentage paces his team.

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