Tennessee vs Vanderbilt Prediction, Odds, Picks, Best Bets for Week 14 2025

The Tennessee Volunteers are among the college football teams busy on Saturday, versus the Vanderbilt Commodores.

Before you make your wager on FanDuel Sportsbook, we've got you covered, in terms of the most important information about today's NCAA football betting odds.

Tennessee vs Vanderbilt Odds & Spread

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• All college football odds, betting lines and prop bets are available on FanDuel Sportsbook.
• Moneyline: Tennessee: (-146) | Vanderbilt: (+124)
• Spread: Tennessee: -2.5 (-115) | Vanderbilt: +2.5 (-105)
• Total: 66.5 -- Over: (-110) | Under: (-110)

Tennessee vs Vanderbilt Betting Trends

• Tennessee is 5-6-0 against the spread this year.
• Tennessee's ATS record as 2.5-point or bigger favorites is 4-5.
• Out of 11 Tennessee games so far this year, seven have gone over the total.
• Vanderbilt is 9-2-0 against the spread this year.
• Vanderbilt's ATS record as 2.5-point underdogs or more is 3-1.
• Vanderbilt has played 11 games this year, and seven of them have hit the over.

Tennessee vs Vanderbilt Prediction & Pick

All college football win probability predictions and picks are according to numberFire.
Prediction: Volunteers win (50.2%)

Tennessee vs Vanderbilt Point Spread

Tennessee is favored by 2.5 points over Vanderbilt. Tennessee is -115 to cover the spread, with Vanderbilt being -105.

Tennessee vs Vanderbilt Over/Under

The Tennessee-Vanderbilt matchup on Nov. 29 has been given an over/under of 66.5 points. The over is -110 and the under is -110.

Tennessee vs Vanderbilt Moneyline

Vanderbilt is a +124 underdog on the moneyline, while Tennessee is a -146 favorite.

Tennessee vs. Vanderbilt Points Insights

Tennessee vs. Vanderbilt Game Info

• Game day: Saturday, November 29, 2025
• Game time: 3:30 p.m. ET
• TV channel: ESPN
• Location: Knoxville, Tennessee
• Stadium: Neyland Stadium

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Check out even more in-depth Tennessee vs. Vanderbilt analysis on FanDuel Research.