Syracuse vs UConn Prediction, Odds, Picks, Best Bets for Week 2 2025

The college football schedule on Saturday includes the Syracuse Orange facing the UConn Huskies.

We've got you covered, in terms of the vital information about NCAA football betting lines, before you make your wager on FanDuel Sportsbook.

Syracuse vs UConn Odds & Spread

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• All college football odds, betting lines and prop bets are available on FanDuel Sportsbook.
• Moneyline: Syracuse: (-250) | UConn: (+202)
• Spread: Syracuse: -6.5 (-122) | UConn: +6.5 (100)
• Total: 57.5 -- Over: (-110) | Under: (-110)

Syracuse vs UConn Betting Trends

• Syracuse has no wins against the spread this year.
• Every Syracuse game has hit the over this season.
• UConn has one win against the spread this year.
• UConn and its opponent have yet to finish under the total this season.

Syracuse vs UConn Prediction & Pick

All college football win probability predictions and picks are according to numberFire.
Prediction: Orange win (69.6%)

Syracuse vs UConn Point Spread

Syracuse is favored by 6.5 points (-122 to cover) in this matchup. UConn, the underdog, is +100.

Syracuse vs UConn Over/Under

A total of 57.5 points has been set for the Syracuse-UConn game on Sept. 6, with the over available at -110 and the under at -110.

Syracuse vs UConn Moneyline

UConn is the underdog, +202 on the moneyline, while Syracuse is a -250 favorite.

Syracuse vs. UConn Points Insights

• The average implied total for the Orange last season was 33.4 points, 1.4 more points than their implied total of 32 points in Saturday's game.
• The average implied point total last season for the Huskies (29.3) is 3.3 more points than the team's implied total in this matchup (26).

Syracuse vs. UConn Game Info

• Game day: Saturday, September 6, 2025
• Game time: 12 p.m. ET
• TV channel: ACC Network Extra
• Location: Syracuse, New York
• Stadium: JMA Wireless Dome

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