Spurs vs. Cavaliers Prediction, Odds, Picks, Best Bets for Dec. 29

Spurs vs. Cavaliers Game Info

• Date: Monday, December 29, 2025
• Time: 8 p.m. ET
• Venue: Frost Bank Center -- San Antonio, Texas
• Coverage: NBC/Peacock

The Cleveland Cavaliers (17-16) are underdogs (by 5 points) to end a three-game road losing streak when they visit the San Antonio Spurs (23-8) on Monday, December 29, 2025 at 8 p.m. ET. The matchup's point total is set at 242.5.

Spurs vs. Cavaliers Odds & Spread

All NBA betting lines, odds and prop bets are from FanDuel Sportsbook.

Spurs vs. Cavaliers Prediction & Pick

All NBA win probability predictions and picks are according to numberFire.
Prediction: Spurs win (56.4%)

Spurs vs. Cavaliers Betting Trends

• The Spurs have compiled a 16-12-3 record against the spread this season.
• Against the spread, the Cavaliers are 11-22-0 this year.
• This season, Spurs games have hit the over 15 times out of 33 chances.
• Cavaliers games this year have hit the over 16 times in 33 opportunities (48.5%).
• Against the spread, San Antonio has fared better at home, covering eight times in 14 home games, and eight times in 17 road games.
• The Spurs have exceeded the total in a lower percentage of home games (42.9%) than road games (52.9%).
• Cleveland has performed better against the spread away (5-9-0) than at home (6-13-0) this year.
• Cavaliers games have finished above the over/under less often at home (seven times out of 19) than on the road (nine of 14) this year.

Spurs Leaders

• Victor Wembanyama averages 23.9 points, 11.5 boards and 3.5 assists, shooting 51.8% from the floor and 35.1% from downtown, with 1.4 made treys per game.
• Devin Vassell's numbers on the season are 15.3 points, 4 rebounds and 2.5 assists per game, shooting 42.5% from the floor and 38.5% from downtown, with an average of 2.7 made 3-pointers.
• De'Aaron Fox's numbers on the season are 21.9 points, 3.8 boards and 6.1 assists per contest, shooting 48.2% from the floor and 39.4% from downtown, with an average of 2.4 made treys.
• Stephon Castle's numbers on the season are 18.6 points, 5.1 boards and 7 assists per contest, shooting 50.9% from the field and 28.3% from beyond the arc, with an average of 1.2 made treys.
• Keldon Johnson is averaging 13.3 points, 6.5 rebounds and 1.5 assists. At the other end, he averages 0.6 steals and 0.1 blocked shots.

Cavaliers Leaders

• Donovan Mitchell is averaging 30.2 points, 4.5 boards and 5.4 assists for the Cavaliers.
• The Cavaliers get 18.3 points per game from Evan Mobley, plus 9.1 rebounds and 4 assists.
• The Cavaliers get 13.4 points per game from Jaylon Tyson, plus 5.8 rebounds and 1.9 assists.
• De'Andre Hunter averages 14.8 points, 4.1 boards and 2.1 assists. He is draining 42.5% of his shots from the field and 31.2% from 3-point range, with 1.8 triples per game.
• The Cavaliers get 13.2 points per game from Jarrett Allen, plus 7.3 boards and 2 assists.

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