South Dakota State vs Northwestern Prediction, College Football Picks, Odds & Best Bets

College Football Betting Picks in Summary

• Northwestern -13.5
• Northwestern Team Total Over 31.5
• Under 49.5

South Dakota State travels to Northwestern Saturday night in a real, meaningful mismatch — a -530 moneyline with a team total nearly double what the visitors are projected to score.

All college football odds come from FanDuel Sportsbook's college football betting odds and may change after this article is published.

College Football Predictions and Picks

South Dakota State at Northwestern (Sat, 8:00 p.m. ET)

Northwestern -13.5 (-110)

Northwestern's own team total (31.5) is nearly double South Dakota State's (17.5), a real gap that lines up cleanly with the home favorite number here.

Northwestern Team Total Over 31.5 (+102)

Plus-money on the home team's own number is genuine value, consistent with both the spread and the favorite status on the full-game moneyline.

Under 49.5 (-105)

Adding the two individual team totals together (31.5 and 17.5) lands right at 49 — essentially this exact number — making the under a genuinely fair reflection of how the market expects the scoring to break down.