San Jose State vs Wyoming Prediction, Odds, Picks, Best Bets for Week 6 2026

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Friday's slate in college football includes a matchup between the San Jose State Spartans and the Wyoming Cowboys.

We've got you covered, in terms of the vital information about NCAA football betting lines, before you make your wager on FanDuel Sportsbook.

San Jose State vs Wyoming Odds & Spread

All college football odds, betting lines and prop bets are available on FanDuel Sportsbook.
Moneyline: San Jose State: (-184) | Wyoming: (+152)
Spread: San Jose State: -4.5 (-105) | Wyoming: +4.5 (-115)
Total: 42.5 -- Over: (-105) | Under: (-115)

San Jose State has three wins in five games against the spread this season.
San Jose State has yet to win ATS (0-1) when playing as at least 4.5-point favorites this year.
One of five San Jose State games have hit the over this season.
Wyoming has but one win versus the spread this season.
Wyoming is winless ATS (0-1) when playing as at least 4.5-point underdogs this season.
Wyoming has had one game (of five) go over the total this season.

All college football win probability predictions and picks are according to numberFire.
Prediction: Spartans win (69.5%)

Wyoming is listed as an underdog by 4.5 points (-115 odds), and San Jose State, the favorite, is -105 to cover.

A total of 42.5 points has been set for the San Jose State-Wyoming game on Oct. 9, with the over available at -105 and the under at -115.

The moneyline numbers for San Jose State vs. Wyoming reveal San Jose State as the favorite (-184) and Wyoming as the underdog (+152).

	Point Scored (PG)	Points Scored CFB Rank	Points Allowed (PG)	Points Allowed CFB Rank	Average Total	Total Games
San Jose State	22.6	103	25.0	81	54.7	5
Wyoming	14.2	135	22.0	64	43.9	5

Check out even more in-depth San Jose State vs. Wyoming analysis on FanDuel Research.

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