Sabres vs Blue Jackets NHL Prediction, Odds, Picks, Best Bets for Oct. 28

Tuesday's slate in the NHL includes a matchup between the Buffalo Sabres and the Columbus Blue Jackets.

Before you make your wager on FanDuel Sportsbook, we've got you covered with all the latest NHL betting insights.

Sabres vs Blue Jackets Game Info

• Buffalo Sabres (4-4-1) vs. Columbus Blue Jackets (4-4)
• Date: Tuesday, October 28, 2025
• Time: 6:45 p.m. ET
• Venue: KeyBank Center -- Buffalo, New York
• Coverage: ESPN+

Sabres vs Blue Jackets Odds

All NHL odds, betting lines and prop bets are available on FanDuel Sportsbook.

Sabres vs Blue Jackets Prediction & Pick

All NHL win probability predictions and picks are according to numberFire.

• Prediction: Blue Jackets win (54%)

Sabres vs Blue Jackets Puck Line

• The Sabres are favored by 1.5 goals against the Blue Jackets. The Sabres are +194 to cover the spread, while the Blue Jackets are -245.

Sabres vs Blue Jackets Over/Under

• A total of 6.5 goals has been set for the Sabres-Blue Jackets matchup on Oct. 28, with the over available at -104 and the under at -118.

Sabres vs Blue Jackets Moneyline

• Buffalo is a -120 favorite on the moneyline, while Columbus is a +100 underdog on the road.

Sign up for FanDuel Sportsbook and FanDuel Daily Fantasy today!