Royals vs White Sox Prediction, Odds, Moneyline, Spread & Over/Under for May 7

Odds updated as of 5:13 p.m.

Wednesday's slate in the MLB includes a matchup between the Kansas City Royals and the Chicago White Sox.

All the information you need to make smart wagers on this matchup at FanDuel Sportsbook can be found below. Check out all of the latest MLB betting lines here.

Royals vs White Sox Game Info

• Kansas City Royals (21-16) vs. Chicago White Sox (10-26)
• Date: Wednesday, May 7, 2025
• Time: 7:40 p.m. ET
• Venue: Kauffman Stadium -- Kansas City, Missouri
• Coverage: FDSKC and CHSN

Royals vs White Sox Odds & Moneyline

• All MLB odds, betting lines and prop bets are available on FanDuel Sportsbook.
• Moneyline: KC: (-220) | CHW: (+184)
• Spread: KC: -1.5 (-102) | CHW: +1.5 (-118)
• Total: 8.5 -- Over: (-104) | Under: (-118)

Royals vs White Sox Probable Starting Pitchers

Probable Pitchers: Michael Wacha (Royals) - 1-4, 3.52 ERA vs Jonathan Cannon (White Sox) - 2-3, 4.26 ERA

The Royals will give the nod to Michael Wacha (1-4, 3.52 ERA), who is eyeing win No. 2 on the season, and the White Sox will counter with Jonathan Cannon (2-3, 4.26 ERA). Wacha's team is 3-4-0 against the spread in his starts this season. When Wacha starts a game and his team is the favorite on the moneyline, they have a record of 1-2. The White Sox have a 2-4-0 record against the spread in Cannon's starts. The White Sox have a 1-5 record in Cannon's six starts this season when they were the moneyline underdog.

Royals vs White Sox Prediction & Pick

All MLB win probability predictions and picks are according to numberFire.
Prediction: Royals win (64.7%)

Royals vs White Sox Moneyline

• Looking at the moneyline for Royals-White Sox, Kansas City is the favorite at -220, and Chicago is +184 playing on the road.

Royals vs White Sox Spread

• The White Sox are at the Royals, and are +1.5 on the runline. The White Sox are -102 to cover the spread, and the Royals are -118.

Royals vs White Sox Over/Under

• The over/under for the Royals versus White Sox contest on May 7 has been set at 8.5, with -104 odds on the over and -118 odds on the under.

Bet on Kansas City Royals vs. Chicago White Sox on FanDuel today!

Royals vs White Sox Betting Trends

• The Royals have been chosen as favorites in 15 games this year and have walked away with the win 11 times (73.3%) in those games.
• Kansas City has not lost in four games this year when favored by -220 or better on the moneyline.
• Contests with the Royals have gone over the total set by bookmakers in 12 of 37 chances this season.
• The Royals have an against the spread mark of 19-18-0 in 37 games with a line this season.
• The White Sox have gone 10-26 in games they were the underdog on the moneyline (winning 27.8% of those games).
• When playing as a moneyline underdog with odds of +184 or longer, Chicago has a record of 4-13 (23.5%).
• The White Sox have had an over/under set by bookmakers 36 times, and have combined with opponents to go over the total in 17 of those games (17-17-2).
• The White Sox have gone 19-17-0 against the spread this season.

Royals Player Leaders

• Bobby Witt Jr. has 44 hits to go with a slugging percentage of .493, both of which are tops among Kansas City hitters this season. He has a .310 batting average and an on-base percentage of .383.
• Among all qualified hitters in the majors, he is 15th in batting average, 24th in on-base percentage, and 28th in slugging.
• Witt hopes to build on a three-game hitting streak in this matchup. During his last five outings he is batting .238 with two doubles, a home run, a walk and four RBIs.
• Maikel Garcia leads Kansas City in OBP (.386) this season, fueled by 39 hits. He's batting .315 while slugging .484.
• Among qualifying hitters, his batting average ranks him 11th, his on-base percentage 20th, and his slugging percentage 32nd.
• Vinnie Pasquantino has 28 hits this season and has a slash line of .201/.258/.381.
• Salvador Perez has been key for Kansas City with 31 hits, an OBP of .290 plus a slugging percentage of .380.

White Sox Player Leaders

• Luis Robert has racked up 22 hits, a team-high for the White Sox. He's batting .188 and slugging .342 with an on-base percentage of .304.
• Including all qualified hitters in the majors, he ranks 150th in batting average, 106th in on-base percentage and 129th in slugging percentage.
• Miguel Vargas has a .315 OBP to pace his team. He has a batting average of .216 while slugging .312.
• His batting average is 128th among all qualified players, his on-base percentage ranks 95th, and he is 146th in slugging.
• Andrew Benintendi is batting .224 with five home runs and eight walks.
• Brooks Baldwin is hitting .250 with five doubles, three home runs and five walks.

Royals vs White Sox Head to Head

• 5/6/2025: 4-3 KC (Favorite: Royals, Spread: -1.5, Total: 8.5, Favorite Moneyline: -255, Underdog Moneyline: +210)
• 5/5/2025: 3-0 KC (Favorite: Royals, Spread: -1.5, Total: 7.5, Favorite Moneyline: -220, Underdog Moneyline: +184)
• 7/31/2024: 10-3 KC (Favorite: Royals, Spread: -1.5, Total: 8.5, Favorite Moneyline: -235, Underdog Moneyline: +194)
• 7/30/2024: 4-3 KC (Favorite: Royals, Spread: -1.5, Total: 8.5, Favorite Moneyline: -186, Underdog Moneyline: +156)
• 7/29/2024: 8-5 KC (Favorite: Royals, Spread: -1.5, Total: 9.5, Favorite Moneyline: -174, Underdog Moneyline: +146)
• 7/21/2024: 4-1 KC (Favorite: Royals, Spread: -1.5, Total: 8, Favorite Moneyline: -230, Underdog Moneyline: +190)
• 7/20/2024: 6-1 KC (Favorite: Royals, Spread: -1.5, Total: 8.5, Favorite Moneyline: -235, Underdog Moneyline: +194)
• 7/19/2024: 7-1 KC (Favorite: Royals, Spread: -1.5, Total: 8.5, Favorite Moneyline: -235, Underdog Moneyline: +194)
• 4/17/2024: 2-1 CHW (Favorite: Royals, Spread: -1.5, Total: 8.5, Favorite Moneyline: -168, Underdog Moneyline: +142)
• 4/17/2024: 4-2 KC (Favorite: Royals, Spread: -1.5, Total: 9, Favorite Moneyline: -190, Underdog Moneyline: +160)

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