Reds vs White Sox Prediction, Odds, Moneyline, Spread & Over/Under for May 13

Odds updated as of 5:17 a.m.

The Cincinnati Reds will take on the Chicago White Sox in MLB action on Tuesday.

We've got you covered, in terms of the most important information regarding this game before you take a look at the MLB odds and spreads on FanDuel Sportsbook.

Reds vs White Sox Game Info

• Cincinnati Reds (20-22) vs. Chicago White Sox (12-29)
• Date: Tuesday, May 13, 2025
• Time: 6:40 p.m. ET
• Venue: Great American Ball Park -- Cincinnati, Ohio
• Coverage: FDSOH and CHSN

Reds vs White Sox Odds & Moneyline

• All MLB odds, betting lines and prop bets are available on FanDuel Sportsbook.
• Moneyline: CIN: (-198) | CHW: (+166)
• Spread: CIN: -1.5 (-102) | CHW: +1.5 (-118)
• Total: 9 -- Over: (-124) | Under: (+102)

Reds vs White Sox Probable Starting Pitchers

Probable Pitchers: Andrew Abbott (Reds) - 2-0, 2.25 ERA vs Jonathan Cannon (White Sox) - 2-4, 4.09 ERA

This contest's pitching matchup is set, as the Reds will send Andrew Abbott (2-0) to the mound, while Jonathan Cannon (2-4) will get the nod for the White Sox. Abbott and his team have a record of 4-1-0 against the spread when he starts. Abbott's team is 2-0 this season when he starts and they're favored on the moneyline. The White Sox have gone 3-4-0 ATS in Cannon's seven starts that had a set spread. The White Sox are 1-6 in Cannon's seven starts this season that they were the underdog on the moneyline.

Reds vs White Sox Prediction & Pick

All MLB win probability predictions and picks are according to numberFire.
Prediction: Reds win (66.6%)

Reds vs White Sox Moneyline

• The Reds vs White Sox moneyline has Cincinnati as a -198 favorite, while Chicago is a +166 underdog on the road.

Reds vs White Sox Spread

• The White Sox are at +1.5 on the runline against the Reds. The White Sox are -118 to cover the spread, and the Reds are -102.

Reds vs White Sox Over/Under

• The Reds-White Sox game on May 13 has been given an over/under of 9 runs. The over is set at -124 and the under at +102.

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Reds vs White Sox Betting Trends

• The Reds have won in nine, or 56.2%, of the 16 contests they have been named as odds-on favorites in this year.
• Cincinnati has played as a favorite of -198 or more just one time this year and came away with a win in that game.
• The Reds and their opponents have gone over in 18 of their 41 games with a total set by sportsbooks this season.
• The Reds have an against the spread record of 21-20-0 in 41 games with a line this season.
• The White Sox have a 12-28 record in games they were listed as the moneyline underdog (winning 30% of those games).
• Chicago is 4-16 (winning only 20% of its games) when playing as a moneyline underdog of +166 or longer.
• The White Sox have played in 41 games with an over/under set, and have combined with opponents to go over the total 19 times (19-20-2).
• The White Sox are 22-19-0 against the spread this season.

Reds Player Leaders

• TJ Friedl leads Cincinnati with a slugging percentage of .385, fueled by 10 extra-base hits. He has a .276 batting average and an on-base percentage of .358.
• Among all qualified hitters in the majors, he is 48th in batting average, 44th in on-base percentage, and 104th in slugging.
• Elly De La Cruz has five doubles, six home runs and 17 walks. He's batting .244 and slugging .384 with an on-base percentage of .321.
• He is 97th in batting average, 89th in on-base percentage and 107th in slugging among qualifying batters.
• Gavin Lux leads his team in OBP (.377) and total hits (37) this season.
• Jose Trevino has three home runs, 10 RBI and a batting average of .310 this season.
• Trevino has hit safely in two games in a row. In his last five games he is batting .263 with four doubles and an RBI.

White Sox Player Leaders

• Luis Robert has three doubles, five home runs and 20 walks while batting .186. He's slugging .326 with an on-base percentage of .293.
• Including all the qualifying players in MLB, his batting average is 154th, his on-base percentage is 124th, and he is 141st in slugging.
• Miguel Vargas has a .312 on-base percentage to lead his team. He has a batting average of .215 while slugging .319.
• He is 135th in batting average, 102nd in on-base percentage and 145th in slugging percentage in the majors.
• Andrew Vaughn is batting .191 with six doubles, five home runs and seven walks.
• Matthew Thaiss is hitting .224 with four doubles, a home run and 18 walks.

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