Reds vs Pirates Prediction, Odds, Moneyline, Spread & Over/Under for May 19

Odds updated as of 5:13 a.m.

The Cincinnati Reds versus the Pittsburgh Pirates is on the MLB schedule for Monday.

All the info you need to make smart wagers on this matchup at FanDuel Sportsbook can be found below. Check out all of the latest MLB betting lines here.

Reds vs Pirates Game Info

• Cincinnati Reds (24-24) vs. Pittsburgh Pirates (15-32)
• Date: Monday, May 19, 2025
• Time: 6:40 p.m. ET
• Venue: PNC Park -- Pittsburgh, Pennsylvania
• Coverage: Fox Sports 1, SportsNet PT, and FDSOH

Reds vs Pirates Odds & Moneyline

• All MLB odds, betting lines and prop bets are available on FanDuel Sportsbook.
• Moneyline: CIN: (-122) | PIT: (+104)
• Spread: CIN: -1.5 (+140) | PIT: +1.5 (-172)
• Total: 8 -- Over: (-110) | Under: (-110)

Reds vs Pirates Probable Starting Pitchers

Probable Pitchers: Nick Lodolo (Reds) - 3-4, 3.42 ERA vs Mitch Keller (Pirates) - 1-5, 4.15 ERA

This contest's pitching matchup is set, as the Reds will send Nick Lodolo (3-4) to the mound, while Mitch Keller (1-5) will take the ball for the Pirates. Lodolo's team is 5-4-0 against the spread in his starts this season. Lodolo's team has been victorious in 40% of the games he's started as the moneyline favorite with a record of 2-3. The Pirates have a 3-6-0 record against the spread in Keller's starts. The Pirates are 1-5 in Keller's six starts this season that they were the underdog on the moneyline.

Reds vs Pirates Prediction & Pick

All MLB win probability predictions and picks are according to numberFire.
Prediction: Reds win (57.8%)

Reds vs Pirates Moneyline

• Pittsburgh is a +104 underdog on the moneyline, while Cincinnati is a -122 favorite on the road.

Reds vs Pirates Spread

• The Pirates are +1.5 on the spread (-172 to cover), and Cincinnati is +140 to cover the runline.

Reds vs Pirates Over/Under

• The over/under for the Reds versus Pirates contest on May 19 has been set at 8, with -110 odds on the over and -110 odds on the under.

Bet on Cincinnati Reds vs. Pittsburgh Pirates on FanDuel today!

Reds vs Pirates Betting Trends

• The Reds have been chosen as favorites in 19 games this year and have walked away with the win 11 times (57.9%) in those games.
• Cincinnati has a record of 8-5 in contests when oddsmakers favor them by -122 or more on the moneyline.
• The Reds and their opponents have hit the over in 18 of their 46 games with a total set by oddsmakers this season.
• The Reds are 25-21-0 against the spread in their 46 games with a line set by sportsbooks this season.
• The Pirates have won 10 of the 30 games they were listed as the moneyline underdog this season (33.3%).
• When it has played as a moneyline underdog with odds of +104 or longer, Pittsburgh has an 8-19 record (winning only 29.6% of its games).
• In the 45 games oddsmakers have set an over/under for the Pirates, they have combined with opponents to go over the total 17 times (17-26-2).
• The Pirates have gone 18-27-0 against the spread this season.

Reds Player Leaders

• Elly De La Cruz leads Cincinnati with 46 hits and a team-best slugging percentage of .406. He's batting .246 with an on-base percentage of .317.
• Among all qualifying batters in the majors, he ranks 99th in batting average, 101st in on-base percentage, and 90th in slugging.
• TJ Friedl is hitting .265 with seven doubles, a triple, three home runs and 23 walks. He's slugging .373 with an on-base percentage of .358.
• Among qualified hitters, he ranks 60th in batting average, 46th in on-base percentage and 116th in slugging percentage.
• Gavin Lux leads Cincinnati in OBP (.379) this season, fueled by 43 hits.
• Austin Hays is batting .313 with a .363 OBP and 17 RBI for Cincinnati this season.
• Hays takes a five-game hitting streak into this game. During his last five outings he is hitting .333 with two doubles, a home run, a walk and four RBIs.

Pirates Player Leaders

• Oneil Cruz has totaled 31 hits, a team-high for the Pirates. He's batting .223 and slugging .432 with an on-base percentage of .349.
• Including all qualifying hitters in the majors, he is 129th in batting average, 57th in on-base percentage and 70th in slugging percentage.
• Andrew McCutchen is hitting .248 with seven doubles, three home runs and 20 walks. He's slugging .368 with an on-base percentage of .348.
• His batting average is 94th among all qualified players, his on-base percentage ranks 61st, and he is 121st in slugging.
• Bryan Reynolds is hitting .203 with five doubles, six home runs and 16 walks.
• Ke'Bryan Hayes paces his team with a .311 slugging percentage.

Reds vs Pirates Head to Head

• 4/13/2025: 4-0 CIN (Favorite: Reds, Spread: -1.5, Total: 7.5, Favorite Moneyline: -188, Underdog Moneyline: +158)
• 4/12/2025: 5-2 CIN (Favorite: Reds, Spread: -1.5, Total: 8.5, Favorite Moneyline: -124, Underdog Moneyline: +106)
• 4/11/2025: 5-3 CIN (Favorite: Reds, Spread: -1.5, Total: 8, Favorite Moneyline: -168, Underdog Moneyline: +142)
• 9/22/2024: 2-0 PIT (Favorite: Reds, Spread: -1.5, Total: 8, Favorite Moneyline: -110, Underdog Moneyline: -106)
• 9/21/2024: 7-1 CIN (Favorite: Reds, Spread: -1.5, Total: 9, Favorite Moneyline: -120, Underdog Moneyline: +102)
• 9/20/2024: 8-3 CIN (Favorite: Reds, Spread: -1.5, Total: 9, Favorite Moneyline: -126, Underdog Moneyline: +108)
• 8/25/2024: 4-3 PIT (Favorite: Pirates, Spread: -1.5, Total: 8.5, Favorite Moneyline: -108, Underdog Moneyline: -108)
• 8/24/2024: 10-2 CIN (Favorite: Pirates, Spread: -1.5, Total: 9, Favorite Moneyline: -108, Underdog Moneyline: -108)
• 8/23/2024: 6-5 PIT (Favorite: Pirates, Spread: -1.5, Total: 8, Favorite Moneyline: -112, Underdog Moneyline: -104)
• 8/22/2024: 7-0 PIT (Favorite: Pirates, Spread: -1.5, Total: 7, Favorite Moneyline: -148, Underdog Moneyline: +126)

Sign up for FanDuel Sportsbook and FanDuel Daily Fantasy today!