Reds vs Giants Prediction, Odds, Moneyline, Spread & Over/Under for March 29

Odds updated as of 4:14 p.m.

On Saturday in MLB, the Cincinnati Reds are playing the San Francisco Giants.

All the info you need to make smart bets on this game at FanDuel Sportsbook can be found below. Check out all of the latest MLB betting lines here.

Reds vs Giants Game Info

• Cincinnati Reds (0-1) vs. San Francisco Giants (1-0)
• Date: Saturday, March 29, 2025
• Time: 4:10 p.m. ET
• Venue: Great American Ball Park -- Cincinnati, Ohio
• Coverage: FDSOH and NBCS-BA

Reds vs Giants Odds & Moneyline

• All MLB odds, betting lines and prop bets are available on FanDuel Sportsbook.
• Moneyline: CIN: (-118) | SF: (-100)
• Spread: CIN: +1.5 (-192) | SF: -1.5 (+158)
• Total: 8.5 -- Over: (-115) | Under: (-105)

Reds vs Giants Probable Starting Pitchers

Probable Pitchers: Nick Lodolo (Reds) - 0-0, 0.00 ERA vs Justin Verlander (Giants) - 0-0, 0.00 ERA

The Reds will call on Nick Lodolo against the Giants and Justin Verlander. Lodolo and his team were 10-11-0 ATS in games he pitched last year. Lodolo appeared in 16 games last season as the moneyline favorite and his team finished with a record of 9-7 in those contests. Last season Verlander and his team went 7-10-0 against the spread in games he pitched. Verlander and his team went 2-2 in the four games he pitched when they were the underdog on the moneyline a season ago.

Reds vs Giants Prediction & Pick

All MLB win probability predictions and picks are according to numberFire.
Prediction: Reds win (58%)

Reds vs Giants Moneyline

• San Francisco is the underdog, -100 on the moneyline, while Cincinnati is a -118 favorite at home.

Reds vs Giants Spread

• The Giants are 1.5-run favorites against the spread for this matchup with the Reds. The Giants are +158 to cover, while the Reds are -192 to cover as a 1.5-run underdog on the runline.

Reds vs Giants Over/Under

• The over/under for the Reds versus Giants contest on March 29 has been set at 8.5, with -115 odds on the over and -105 odds on the under.

Bet on Cincinnati Reds vs. San Francisco Giants on FanDuel today!

Reds vs Giants Betting Trends

• The Reds were victorious in 37, or 54.4%, of the 68 contests they were chosen as favorites last season.
• Last season Cincinnati came away with a win 30 times in 56 chances when named as a favorite of at least -118 or shorter on the moneyline.
• The Reds and their opponents hit the over in 72 of their 156 games with a total last season.
• The Giants put together a 32-41 record in games last season when they were the underdog on the moneyline (winning 43.8% of those games).
• When playing as a moneyline underdog with odds of -100 or longer last year, San Francisco went 24-34 (41.4%).
• The Giants combined with their opponents to hit the over on the total 82 times last season for an 82-73-5 record against the over/under.

Reds Player Leaders

• Elly De La Cruz collected 160 hits, posted an OBP of .339 and a .471 SLG last season.
• Spencer Steer slashed .225/.319/.402 and finished with an OPS of .721.
• Last season, Gavin Lux finished with 10 home runs, 50 RBI and a batting average of .251 last season.
• Jeimer Candelario slashed .225/.279/.429 and finished with an OPS of .707.

Giants Player Leaders

• Willy Adames accumulated an on-base percentage of .331 and a slugging percentage of .462 a season ago.
• Matt Chapman hit .247 with 39 doubles, two triples, 27 home runs and 64 walks.
• Heliot Ramos had 128 hits and a batting average of .269 a season ago.
• Mike Yastrzemski hit .231 with 16 doubles, nine triples, 18 home runs and 38 walks.

Reds vs Giants Head to Head

• 3/27/2025: 6-4 SF (Favorite: Giants, Spread: -1.5, Total: 7.5, Favorite Moneyline: -110, Underdog Moneyline: -106)
• 8/4/2024: 8-2 SF (Favorite: Reds, Spread: -1.5, Total: 9, Favorite Moneyline: -112, Underdog Moneyline: -104)
• 8/3/2024: 6-4 CIN (Favorite: Reds, Spread: -1.5, Total: 9, Favorite Moneyline: -136, Underdog Moneyline: +116)
• 5/12/2024: 6-5 SF (Favorite: Giants, Spread: -1.5, Total: 7.5, Favorite Moneyline: -122, Underdog Moneyline: +104)
• 5/11/2024: 5-1 SF (Favorite: Reds, Spread: -1.5, Total: 7.5, Favorite Moneyline: -144, Underdog Moneyline: +122)
• 5/10/2024: 4-2 CIN (Favorite: Giants, Spread: -1.5, Total: 7, Favorite Moneyline: -146, Underdog Moneyline: +124)
• 8/30/2023: 4-1 CIN (Favorite: Giants, Spread: -1.5, Total: 7, Favorite Moneyline: -174, Underdog Moneyline: +146)
• 8/29/2023: 6-1 SF (Favorite: Giants, Spread: -1.5, Total: 7.5, Favorite Moneyline: -166, Underdog Moneyline: +140)
• 8/28/2023: 4-1 SF (Favorite: Giants, Spread: -1.5, Total: 8.5, Favorite Moneyline: -134, Underdog Moneyline: +114)
• 7/20/2023: 5-1 CIN (Favorite: Reds, Spread: -1.5, Total: 9, Favorite Moneyline: -116, Underdog Moneyline: -102)

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