Reds vs Cardinals Prediction, Odds, Moneyline, Spread & Over/Under for Aug. 19

Odds updated as of 5:12 a.m.

The MLB slate on Wednesday includes the Cincinnati Reds taking on the St. Louis Cardinals.

Here's what you need to know before checking out today's MLB odds and spreads on FanDuel Sportsbook.

Reds vs Cardinals Game Info

• Cincinnati Reds (60-66) vs. St. Louis Cardinals (65-62)
• Date: Wednesday, August 19, 2026
• Time: 6:40 p.m. ET
• Venue: Great American Ball Park -- Cincinnati, Ohio
• Coverage: Reds.TV and Cardinals.TV

Reds vs Cardinals Odds & Moneyline

• All MLB odds, betting lines and prop bets are available on FanDuel Sportsbook.
• Moneyline: CIN: (-146) | STL: (+124)
• Spread: CIN: -1.5 (+142) | STL: +1.5 (-172)
• Total: 8.5 -- Over: (-106) | Under: (-114)

Reds vs Cardinals Probable Starting Pitchers

Probable Pitchers: Chase Burns (Reds) - 14-2, 2.47 ERA vs Matthew Liberatore (Cardinals) - 5-10, 5.07 ERA

The Reds will give the ball to Chase Burns (14-2, 2.47 ERA), who is eyeing win No. 15 on the season, and the Cardinals will turn to Matthew Liberatore (5-10, 5.07 ERA). Burns and his team have a record of 17-6-0 against the spread when he starts. Burns' team is 12-5 this season when he starts and they are the moneyline favorite. The Cardinals have an 11-12-0 record against the spread in Liberatore's starts. The Cardinals have been the moneyline underdog in 16 of Liberatore's starts this season, and they went 8-8 in those matchups.

Reds vs Cardinals Prediction & Pick

All MLB win probability predictions and picks are according to numberFire.
Prediction: Reds win (53.5%)

Reds vs Cardinals Moneyline

• The moneyline numbers for Reds vs. Cardinals reveal Cincinnati as the favorite (-146) and St. Louis as the underdog (+124) on the road.

Reds vs Cardinals Spread

• The Reds are hosting the Cardinals and are favored by 1.5 runs on the spread. The Reds are +142 to cover the runline, with the Cardinals being -172.

Reds vs Cardinals Over/Under

• An over/under of 8.5 has been set for Reds-Cardinals on Aug. 19, with the over being -106 and the under -114.

Bet on Cincinnati Reds vs. St. Louis Cardinals on FanDuel today!

Reds vs Cardinals Betting Trends

• The Reds have been chosen as favorites in 39 games this year and have walked away with the win 21 times (53.8%) in those games.
• Cincinnati has a record of 8-5 in contests when oddsmakers favor them by -146 or more on the moneyline.
• The Reds' games have gone over the total in 64 of their 123 opportunities.
• The Reds are 65-58-0 against the spread in their 123 games with a line set by sportsbooks this season.
• The Cardinals have a 40-43 record in games they were the underdog on the moneyline (winning 48.2% of those games).
• St. Louis has a record of 14-13 when it has played as a moneyline underdog with odds of +124 or longer (51.9%).
• The Cardinals have combined with opponents to go over the total 49 times this season for a 49-67-7 record against the over/under.
• The Cardinals have a 66-57-0 record against the spread this season (covering 53.7% of the time).

Reds Player Leaders

• Sal Stewart leads Cincinnati in slugging percentage (.471) and total hits (124) this season. He's batting .258 with an on-base percentage of .333.
• Among qualifying hitters in MLB, his batting average ranks 68th, his on-base percentage ranks 70th, and he is 32nd in slugging.
• Stewart hopes to build on a three-game hitting streak in this matchup. In his last five games he is batting .250 with a double and two RBIs.
• Elly De La Cruz has 109 hits this season and a team-best OBP of .341. He's batting .259 and slugging .470.
• Among all qualified, he is 64th in batting average, 59th in on-base percentage and 33rd in slugging percentage.
• JJ Bleday has collected 76 base hits, an OBP of .333 and a slugging percentage of .438 this season.
• Tyler Stephenson has 12 home runs, 39 RBI and a batting average of .245 this season.

Cardinals Player Leaders

• Alec Burleson has a .493 slugging percentage, which paces the Cardinals. He's batting .289 with an on-base percentage of .354.
• Including all the qualifying hitters in the big leagues, his batting average places him 15th, his on-base percentage ranks 41st, and he is 21st in slugging.
• Burleson hopes to build on a five-game hitting streak in this matchup. In his last five games he is batting .381 with three doubles, two home runs, a walk and eight RBIs.
• Jordan Walker has collected 138 hits to pace his team. He has a batting average of .289 while slugging .498 with an on-base percentage of .347.
• Including all qualifying hitters, his batting average puts him 15th, his on-base percentage ranks 49th, and he is 16th in slugging.
• JJ Wetherholt is hitting .241 with 13 doubles, 16 home runs and 62 walks.
• Ivan Herrera leads his team with a .361 OBP.

Reds vs Cardinals Head to Head

• 8/18/2026: 3-0 STL (Favorite: Cardinals, Spread: -1.5, Total: 9, Favorite Moneyline: -112, Underdog Moneyline: +104)
• 8/17/2026: 6-5 CIN (Favorite: Cardinals, Spread: -1.5, Total: 9, Favorite Moneyline: -116, Underdog Moneyline: +108)
• 8/17/2026: 2-1 STL (Favorite: Cardinals, Spread: -1.5, Total: 9.5, Favorite Moneyline: -110, Underdog Moneyline: +100)
• 7/26/2026: 5-3 CIN (Favorite: Cardinals, Spread: -1.5, Total: 8.5, Favorite Moneyline: -132, Underdog Moneyline: +112)
• 7/25/2026: 7-0 STL (Favorite: Cardinals, Spread: -1.5, Total: 8, Favorite Moneyline: -112, Underdog Moneyline: -104)
• 7/24/2026: 4-2 CIN (Favorite: Cardinals, Spread: -1.5, Total: 8, Favorite Moneyline: -152, Underdog Moneyline: +128)
• 6/7/2026: 5-3 STL (Favorite: Cardinals, Spread: -1.5, Total: 9.5, Favorite Moneyline: -152, Underdog Moneyline: +128)
• 6/6/2026: 6-5 STL (Favorite: Cardinals, Spread: -1.5, Total: 9, Favorite Moneyline: -126, Underdog Moneyline: +108)
• 6/5/2026: 10-3 STL (Favorite: Cardinals, Spread: -1.5, Total: 9.5, Favorite Moneyline: -142, Underdog Moneyline: +120)
• 5/23/2026: 7-6 CIN (Favorite: Cardinals, Spread: -1.5, Total: 9.5, Favorite Moneyline: -110, Underdog Moneyline: -106)

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