Red Sox vs White Sox Prediction, Odds, Moneyline, Spread & Over/Under for April 20

Odds updated as of 1:11 p.m.

MLB action on Sunday includes the Boston Red Sox facing the Chicago White Sox.

We've got you covered, in terms of the vital info about this matchup before you take a look at the MLB odds and spreads on FanDuel Sportsbook.

Red Sox vs White Sox Game Info

• Boston Red Sox (12-10) vs. Chicago White Sox (4-16)
• Date: Sunday, April 20, 2025
• Time: 1:35 p.m. ET
• Venue: Fenway Park -- Boston, Massachusetts
• Coverage: NESN and CHSN

Red Sox vs White Sox Odds & Moneyline

• All MLB odds, betting lines and prop bets are available on FanDuel Sportsbook.
• Moneyline: BOS: (-290) | CHW: (+235)
• Spread: BOS: -1.5 (-137) | CHW: +1.5 (+114)
• Total: 9.5 -- Over: (-106) | Under: (-114)

Red Sox vs White Sox Probable Starting Pitchers

Probable Pitchers: Tanner Houck (Red Sox) - 0-2, 9.16 ERA vs Sean Burke (White Sox) - 1-3, 7.56 ERA

The probable starters are Tanner Houck (0-2) for the Red Sox and Sean Burke (1-3) for the White Sox. Houck's team is 1-3-0 against the spread this season in his starts. Houck's team is 0-2 this season when he starts and they're favored on the moneyline. The White Sox have a 2-2-0 record against the spread in Burke's starts. The White Sox have been the moneyline underdog in four of Burke's starts this season, and they went 1-3 in those matchups.

Red Sox vs White Sox Prediction & Pick

All MLB win probability predictions and picks are according to numberFire.
Prediction: Red Sox win (70.9%)

Red Sox vs White Sox Moneyline

• Chicago is a +235 underdog on the moneyline, while Boston is a -290 favorite at home.

Red Sox vs White Sox Spread

• The White Sox are at the Red Sox, and are +1.5 on the runline. The White Sox are -137 to cover the spread, and the Red Sox are +114.

Red Sox vs White Sox Over/Under

• The over/under for the Red Sox versus White Sox contest on April 20 has been set at 9.5, with -106 odds on the over and -114 odds on the under.

Bet on Boston Red Sox vs. Chicago White Sox on FanDuel today!

Red Sox vs White Sox Betting Trends

• The Red Sox have been victorious in nine, or 60%, of the 15 contests they have been chosen as favorites in this season.
• Boston has played as a favorite of -290 or more just one time this year and came away with a win in that game.
• The Red Sox's games have gone over the total in eight of their 22 opportunities.
• The Red Sox have posted a record of 11-11-0 against the spread this season.
• The White Sox are 4-16 in games they were listed as the moneyline underdog (winning 20% of those games).
• Chicago has played as a moneyline underdog of +235 or longer in only one game this season, which it lost.
• The White Sox have combined with opponents to hit the over on the total eight times this season for an 8-10-2 record against the over/under.
• The White Sox have collected a 10-10-0 record ATS this season.

Red Sox Player Leaders

• Alexander David Bregman has 25 hits, which leads Boston hitters this season, while batting .294 with 11 extra-base hits. He has an on-base percentage of .358 and a slugging percentage of .518.
• Among qualifying batters, he is 37th in batting average, his on-base percentage ranks 54th, and he is 26th in slugging.
• Wilyer Abreu leads Boston in OBP (.413) this season, fueled by 19 hits. He's batting .288 while slugging .500.
• He ranks 46th in batting average, 12th in on-base percentage and 33rd in slugging in the majors.
• Trevor Story leads Boston with 27 hits and a team-best slugging percentage of .518.
• Story has logged a hit or more in two straight games. During his last five outings he is batting .350 with two home runs, a walk and six RBI.
• Kristian Campbell has been key for Boston with 20 hits, an OBP of .398 plus a slugging percentage of .478.

White Sox Player Leaders

• Luis Robert has a double, two home runs and 10 walks while batting .145. He's slugging .258 with an on-base percentage of .260.
• Including all the qualifying hitters in MLB, he is 168th in batting average, 145th in on-base percentage and 162nd in slugging percentage.
• Andrew Sebastian Benintendi is hitting .244 with three home runs and three walks. He's slugging .463 with an on-base percentage of .295.
• Lenyn Sosa has put up a team-best OBP (.304) and slugging percentage (.364), and paces the White Sox in hits (18).
• Brooks Baldwin is batting .241 with a double, two home runs and a walk.

Red Sox vs White Sox Head to Head

• 4/19/2025: 4-3 BOS (Favorite: Red Sox, Spread: -1.5, Total: 9, Favorite Moneyline: -350, Underdog Moneyline: +280)
• 4/18/2025: 10-3 BOS (Favorite: Red Sox, Spread: -1.5, Total: 9, Favorite Moneyline: -225, Underdog Moneyline: +188)
• 4/13/2025: 3-1 BOS (Favorite: Red Sox, Spread: -1.5, Total: 7, Favorite Moneyline: -240, Underdog Moneyline: +198)
• 4/12/2025: 3-2 CHW (Favorite: Red Sox, Spread: -1.5, Total: 7.5, Favorite Moneyline: -162, Underdog Moneyline: +136)
• 4/11/2025: 11-1 CHW (Favorite: Red Sox, Spread: -1.5, Total: 8, Favorite Moneyline: -162, Underdog Moneyline: +136)
• 9/8/2024: 7-2 CHW (Favorite: Red Sox, Spread: -1.5, Total: 10, Favorite Moneyline: -275, Underdog Moneyline: +225)
• 9/7/2024: 7-5 BOS (Favorite: Red Sox, Spread: -1.5, Total: 8.5, Favorite Moneyline: -198, Underdog Moneyline: +166)
• 9/6/2024: 3-1 BOS (Favorite: Red Sox, Spread: -1.5, Total: 8.5, Favorite Moneyline: -290, Underdog Moneyline: +235)
• 6/9/2024: 6-4 BOS (Favorite: Red Sox, Spread: -1.5, Total: 9, Favorite Moneyline: -144, Underdog Moneyline: +122)
• 6/8/2024: 6-1 CHW (Favorite: Red Sox, Spread: -1.5, Total: 8.5, Favorite Moneyline: -240, Underdog Moneyline: +194)

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