Red Sox vs Mariners Prediction, Odds, Moneyline, Spread & Over/Under for April 23

Odds updated as of 6:11 a.m.

The Wednesday schedule in MLB includes a matchup between the Boston Red Sox and the Seattle Mariners.

Before you do any MLB betting on this game at FanDuel Sportsbook, here's what you need to know.

Red Sox vs Mariners Game Info

• Boston Red Sox (14-11) vs. Seattle Mariners (12-11)
• Date: Wednesday, April 23, 2025
• Time: 6:45 p.m. ET
• Venue: Fenway Park -- Boston, Massachusetts
• Coverage: NESN and ROOT Sports NW

Red Sox vs Mariners Odds & Moneyline

• All MLB odds, betting lines and prop bets are available on FanDuel Sportsbook.
• Moneyline: BOS: (-134) | SEA: (+116)
• Spread: BOS: -1.5 (+134) | SEA: +1.5 (-162)
• Total: 10 -- Over: (-112) | Under: (-108)

Red Sox vs Mariners Probable Starting Pitchers

Probable Pitchers: Sean Newcomb (Red Sox) - 0-2, 3.63 ERA vs Emerson Hancock (Mariners) - 0-1, 12.71 ERA

The probable starters are Sean Newcomb (0-2) for the Red Sox and Emerson Hancock (0-1) for the Mariners. When Newcomb starts, his team is 2-2-0 against the spread this season. Newcomb's team is 1-1 this season when he starts and they're favored on the moneyline. Hancock has started two games with set spreads, and the Mariners went 1-1-0. The Mariners were the underdog on the moneyline for one Hancock start this season -- they won.

Red Sox vs Mariners Prediction & Pick

All MLB win probability predictions and picks are according to numberFire.
Prediction: Mariners win (59.2%)

Red Sox vs Mariners Moneyline

• Boston is the favorite, -134 on the moneyline, while Seattle is a +116 underdog on the road.

Red Sox vs Mariners Spread

• The Mariners are +1.5 on the spread (-162 to cover), and Boston is +134 to cover the runline.

Red Sox vs Mariners Over/Under

• A combined run total of 10 has been set for Red Sox-Mariners on April 23, with the over at -112 and the under at -108.

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Red Sox vs Mariners Betting Trends

• The Red Sox have won in 11, or 61.1%, of the 18 contests they have been named as odds-on favorites in this year.
• Boston has a record of 4-4 in contests when sportsbooks favor them by -134 or more on the moneyline.
• The Red Sox's games have gone over the total in 10 of their 25 opportunities.
• The Red Sox have posted a record of 13-12-0 against the spread this season.
• The Mariners have won four of the nine games they were the underdog on the moneyline this season (44.4%).
• Seattle has played as a moneyline underdog of +116 or longer in just two games this season, which it split 1-1.
• The Mariners have combined with opponents to go over the total 11 times this season for an 11-10-2 record against the over/under.
• The Mariners have collected an 11-12-0 record ATS this season (covering 47.8% of the time).

Red Sox Player Leaders

• Alexander David Bregman is batting .302 with nine doubles, four home runs and nine walks. He has an on-base percentage of .376 while slugging .521.
• Among the qualified batters in baseball, his batting average ranks 28th, his on-base percentage ranks 35th, and he is 29th in slugging.
• Bregman will look for his fourth straight game with a hit in this matchup. During his last five outings he is batting .222 with two doubles, five walks and three RBI.
• Wilyer Abreu has 23 hits and an OBP of .419, both of which lead the Red Sox this season. He's batting .299 and slugging .532.
• Among qualifiers, he is 34th in batting average, 13th in on-base percentage and 23rd in slugging percentage.
• Trevor Story has an OPS of .847, fueled by an OBP of .347 and a team-best slugging percentage of .500 this season.
• Kristian Campbell is batting .300 with a .406 OBP and eight RBI for Boston this season.

Mariners Player Leaders

• Cal Raleigh has racked up a team-high slugging percentage (.600) and paces the Mariners in hits (22). He's batting .244 and with an on-base percentage of .346.
• Including all qualified hitters in MLB, his batting average puts him 87th, his on-base percentage is 67th, and he is 10th in slugging.
• Raleigh heads into this matchup on a six-game hitting streak. In his last 10 games he is batting .317 with three doubles, seven home runs, six walks and 13 RBI.
• Randy Arozarena is hitting .193 with six doubles, four home runs and 16 walks. He's slugging .410 with an on-base percentage of .350.
• He is currently 141st in batting average, 63rd in on-base percentage and 88th in slugging percentage among all qualified hitters.
• Julio Rodriguez has three doubles, two triples, three home runs and 13 walks while batting .191.
• Dylan Moore is hitting .300 with a double, five home runs and six walks.

Red Sox vs Mariners Head to Head

• 4/22/2025: 8-3 BOS (Favorite: Red Sox, Spread: -1.5, Total: 9.5, Favorite Moneyline: -122, Underdog Moneyline: +104)
• 7/31/2024: 3-2 BOS (Favorite: Mariners, Spread: -1.5, Total: 9.5, Favorite Moneyline: -112, Underdog Moneyline: -104)
• 7/30/2024: 10-6 SEA (Favorite: Mariners, Spread: -1.5, Total: 10.5, Favorite Moneyline: -118, Underdog Moneyline: -100)
• 7/29/2024: 14-7 BOS (Favorite: Red Sox, Spread: -1.5, Total: 8.5, Favorite Moneyline: -120, Underdog Moneyline: +102)
• 3/31/2024: 5-1 BOS (Favorite: Mariners, Spread: -1.5, Total: 7.5, Favorite Moneyline: -120, Underdog Moneyline: +102)
• 3/30/2024: 4-3 SEA (Favorite: Mariners, Spread: -1.5, Total: 7, Favorite Moneyline: -164, Underdog Moneyline: +138)
• 3/29/2024: 1-0 SEA (Favorite: Mariners, Spread: -1.5, Total: 7, Favorite Moneyline: -156, Underdog Moneyline: +132)
• 3/28/2024: 6-4 BOS (Favorite: Mariners, Spread: -1.5, Total: 7.5, Favorite Moneyline: -154, Underdog Moneyline: +130)
• 8/2/2023: 6-3 SEA (Favorite: Mariners, Spread: -1.5, Total: 8.5, Favorite Moneyline: -126, Underdog Moneyline: +108)
• 8/1/2023: 6-4 BOS (Favorite: Mariners, Spread: -1.5, Total: 8, Favorite Moneyline: -108, Underdog Moneyline: -108)

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