Red Sox vs Guardians Prediction, Odds, Moneyline, Spread & Over/Under for May 31

Odds updated as of 1:12 p.m.

The Sunday slate in MLB includes a matchup between the Cleveland Guardians and the Boston Red Sox.

Here's what you need to know before checking out today's MLB odds and spreads on FanDuel Sportsbook.

Guardians vs Red Sox Game Info

• Cleveland Guardians (34-26) vs. Boston Red Sox (24-33)
• Date: Sunday, May 31, 2026
• Time: 1:40 p.m. ET
• Venue: Progressive Field -- Cleveland, Ohio
• Coverage: CleGuardians.TV and NESN

Guardians vs Red Sox Odds & Moneyline

• All MLB odds, betting lines and prop bets are available on FanDuel Sportsbook.
• Moneyline: CLE: (-116) | BOS: (-102)
• Spread: CLE: +1.5 (-215) | BOS: -1.5 (+176)
• Total: 7 -- Over: (+100) | Under: (-122)

Guardians vs Red Sox Probable Starting Pitchers

Probable Pitchers: Tanner Bibee (Guardians) - 0-7, 4.57 ERA vs Ranger Suarez (Red Sox) - 2-3, 3.02 ERA

The Guardians will give the nod to Tanner Bibee (0-7, 4.57 ERA), who is eyeing win No. 1 on the season, and the Red Sox will turn to Ranger Suarez (2-3, 3.02 ERA). Bibee's team is 1-10-0 against the spread this season in his starts. When Bibee starts a game and his team is the favorite on the moneyline, they have a record of 1-6. The Red Sox have a 4-6-0 ATS record in Suarez's 10 starts with a set spread. The Red Sox were the moneyline underdog for two Suarez starts this season -- they split the games.

Guardians vs Red Sox Prediction & Pick

All MLB win probability predictions and picks are according to numberFire.
Prediction: Red Sox win (56.1%)

Guardians vs Red Sox Moneyline

• The moneyline numbers for Guardians vs. Red Sox reveal Cleveland as the favorite (-116) and Boston as the underdog (-102) on the road.

Guardians vs Red Sox Spread

• The Red Sox are 1.5-run favorites against the spread for this matchup with the Guardians. The Red Sox are +176 to cover, while the Guardians are -215 to cover as a 1.5-run underdog on the runline.

Guardians vs Red Sox Over/Under

• A total of 7 runs has been set for the Guardians-Red Sox game on May 31, with the over available at +100 and the under at -122.

Bet on Cleveland Guardians vs. Boston Red Sox on FanDuel today!

Guardians vs Red Sox Betting Trends

• The Guardians have won in 19, or 57.6%, of the 33 contests they have been named as odds-on favorites in this year.
• This season Cleveland has been victorious 19 times in 33 chances when named as a favorite of at least -116 on the moneyline.
• Contests with the Guardians have gone over the total set by sportsbooks in 28 of 56 chances this season.
• The Guardians are 28-28-0 against the spread in their 56 games with a line set by sportsbooks this season.
• The Red Sox have a 7-13 record in games they were listed as the moneyline underdog (winning 35% of those games).
• When it has played as a moneyline underdog with odds of -102 or longer, Boston has a 7-12 record (winning just 36.8% of its games).
• The Red Sox have had an over/under set by oddsmakers 57 times, and have combined with opponents to go over the total in 26 of those games (26-30-1).
• The Red Sox have put together a 24-33-0 record against the spread this season (covering 42.1% of the time).

Guardians Player Leaders

• Jose Ramirez has 13 doubles, eight home runs and 39 walks while hitting .228. He has an on-base percentage of .344 and a slugging percentage of .397.
• He is 119th in batting average, 59th in on-base percentage, and 90th in slugging among qualifying hitters in the majors.
• Ramirez has recorded a base hit in two straight games. During his last five outings he is batting .250 with two doubles, two walks and four RBIs.
• Chase DeLauter is batting .260 with 11 doubles, a triple, seven home runs and 25 walks, while slugging .430 with an on-base percentage of .339.
• Among all qualifying hitters, he is 66th in batting average, 70th in on-base percentage and 65th in slugging percentage.
• Brayan Rocchio is slashing .288/.371/.408 this season and leads the Guardians with an OPS of .779.
• Angel Martinez has 45 hits, which is tops among Cleveland hitters this season, while batting .243 with 19 extra-base hits.

Red Sox Player Leaders

• Willson Contreras has racked up a team-high OBP (.384), and paces the Red Sox in hits (56). He's batting .286 and slugging.
• Including all qualified players, he is 30th in batting average, while his on-base percentage is 19th and he is 22nd in slugging.
• Wilyer Abreu's .427 slugging percentage leads his team. He has a batting average of .280 with an on-base percentage of .344.
• He ranks 36th in batting average, 59th in on-base percentage and 68th in slugging percentage in the majors.
• Ceddanne Rafaela is batting .275 with 11 doubles, two triples, five home runs and 13 walks.
• Jarren Duran has nine doubles, a triple, nine home runs and 16 walks while hitting .217.

Guardians vs Red Sox Head to Head

• 5/30/2026: 9-1 BOS (Favorite: Guardians, Spread: -1.5, Total: 6.5, Favorite Moneyline: -130, Underdog Moneyline: +110)
• 5/29/2026: 4-3 CLE (Favorite: Guardians, Spread: -1.5, Total: 8, Favorite Moneyline: -124, Underdog Moneyline: +106)
• 9/3/2025: 8-1 CLE (Favorite: Red Sox, Spread: -1.5, Total: 9, Favorite Moneyline: -154, Underdog Moneyline: +130)
• 9/2/2025: 11-7 BOS (Favorite: Red Sox, Spread: -1.5, Total: 7.5, Favorite Moneyline: -270, Underdog Moneyline: +220)
• 9/1/2025: 6-4 BOS (Favorite: Red Sox, Spread: -1.5, Total: 8, Favorite Moneyline: -144, Underdog Moneyline: +122)
• 4/27/2025: 13-3 BOS (Favorite: Red Sox, Spread: -1.5, Total: 7.5, Favorite Moneyline: -118, Underdog Moneyline: -100)
• 4/26/2025: 7-3 BOS (Favorite: Red Sox, Spread: -1.5, Total: 7.5, Favorite Moneyline: -116, Underdog Moneyline: -102)
• 4/26/2025: 5-4 CLE (Favorite: Red Sox, Spread: -1.5, Total: 7.5, Favorite Moneyline: -110, Underdog Moneyline: -106)
• 4/25/2024: 6-4 CLE (Favorite: Guardians, Spread: -1.5, Total: 7.5, Favorite Moneyline: -132, Underdog Moneyline: +112)
• 4/24/2024: 8-0 BOS (Favorite: Guardians, Spread: -1.5, Total: 7.5, Favorite Moneyline: -136, Underdog Moneyline: +116)

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