Rays vs Red Sox Prediction, Odds, Moneyline, Spread & Over/Under for April 16

Odds updated as of 7:11 p.m.

The Wednesday schedule in MLB includes a matchup between the Tampa Bay Rays and the Boston Red Sox.

All the information you need to make smart bets on this game at FanDuel Sportsbook can be found below. Check out all of the latest MLB betting lines here.

Rays vs Red Sox Game Info

• Tampa Bay Rays (8-9) vs. Boston Red Sox (9-10)
• Date: Wednesday, April 16, 2025
• Time: 7:05 p.m. ET
• Venue: George M. Steinbrenner Field -- Tampa, Florida
• Coverage: FDSSUN and NESN

Rays vs Red Sox Odds & Moneyline

• All MLB odds, betting lines and prop bets are available on FanDuel Sportsbook.
• Moneyline: TB: (-130) | BOS: (+110)
• Spread: TB: -1.5 (+152) | BOS: +1.5 (-184)
• Total: 9 -- Over: (-110) | Under: (-110)

Rays vs Red Sox Probable Starting Pitchers

Probable Pitchers: Zack Littell (Rays) - 0-3, 6.88 ERA vs Sean Newcomb (Red Sox) - 0-2, 4.97 ERA

This contest's pitching matchup is set, as the Rays will send Zack Littell (0-3) to the mound, while Sean Newcomb (0-2) will take the ball for the Red Sox. Littell and his team have not covered in any of the three games with a spread he's started this season. Littell's team is 0-2 this season when he starts and they're favored on the moneyline. When Newcomb starts, the Red Sox have gone 1-2-0 against the spread. The Red Sox were the underdog on the moneyline for one Newcomb start this season -- they lost.

Rays vs Red Sox Moneyline

• Tampa Bay is a -130 favorite on the moneyline, while Boston is a +110 underdog on the road.

Rays vs Red Sox Spread

• The Rays are favored by 1.5 runs at home versus the Red Sox. The Rays are +152 to cover the spread, while the Red Sox are -184.

Rays vs Red Sox Over/Under

• A combined run total of 9 has been set for Rays-Red Sox on April 16, with the over at -110 and the under at -110.

Bet on Tampa Bay Rays vs. Boston Red Sox on FanDuel today!

Rays vs Red Sox Betting Trends

• The Rays have come away with seven wins in the 13 contests they have been listed as the favorites in this season.
• This season Tampa Bay has come away with a win six times in 10 chances when named as a favorite of at least -130 on the moneyline.
• The Rays and their opponents have gone over in eight of their 17 games with a total set by sportsbooks this season.
• In 17 games with a line this season, the Rays have a mark of 6-11-0 against the spread.
• The Red Sox are 2-4 in games they were listed as the moneyline underdog (winning 33.3% of those games).
• Boston has played as a moneyline underdog of +110 or longer in only two games this season, which it lost both.
• The Red Sox have played in 19 games with a set over/under, and have combined with opponents to go over the total seven times (7-10-2).
• The Red Sox have a 9-10-0 record ATS this season (covering 47.4% of the time).

Rays Player Leaders

• Jonathan Aranda leads Tampa Bay in OBP (.481), slugging percentage (.761) and total hits (19) this season. He has a .413 batting average.
• Among all qualifying hitters in MLB, he is first in batting average, second in on-base percentage, and first in slugging.
• Aranda hopes to build on a four-game hitting streak in this matchup. During his last five outings he is batting .500 with a double, two home runs, three walks and seven RBI.
• Kameron Misner is batting .395 with four doubles, a triple, three home runs and three walks, while slugging .744 with an on-base percentage of .429.
• Misner heads into this matchup looking to extend his four-game hit streak. During his last five outings he is batting .412 with a double, two home runs, two walks and four RBI.
• Junior Caminero is batting .276 with a .517 slugging percentage and nine RBI this year.
• Yandy Diaz is batting .225 with a .253 OBP and six RBI for Tampa Bay this season.
• Diaz enters this matchup on a five-game hitting streak. During his last five outings he is hitting .364 with a double, two home runs, a walk and four RBI.

Red Sox Player Leaders

• Wilyer Abreu has accumulated an on-base percentage of .437, a team-high for the Red Sox. He's batting .310 and slugging .534.
• Including all qualifying hitters, he is 29th in batting average, while his on-base percentage is sixth and he is 27th in slugging.
• Kristian Campbell is hitting .302 with four doubles, three home runs and 10 walks. He's slugging .508 with an on-base percentage of .392.
• Including all qualified hitters, his batting average places him 33rd, his on-base percentage ranks 24th, and he is 37th in slugging.
• Jarren Duran has three doubles, a triple, a home run and seven walks while hitting .234.
• Trevor Story is hitting .311 with two doubles, three home runs and two walks.

Rays vs Red Sox Head to Head

• 4/15/2025: 7-4 BOS (Favorite: Rays, Spread: -1.5, Total: 9, Favorite Moneyline: -130, Underdog Moneyline: +110)
• 4/14/2025: 16-1 TB (Favorite: Rays, Spread: -1.5, Total: 8.5, Favorite Moneyline: -120, Underdog Moneyline: +102)
• 9/29/2024: 3-1 BOS (Favorite: Red Sox, Spread: -1.5, Total: 7.5, Favorite Moneyline: -108, Underdog Moneyline: -108)
• 9/28/2024: 7-2 TB (Favorite: Red Sox, Spread: -1.5, Total: 7.5, Favorite Moneyline: -118, Underdog Moneyline: -100)
• 9/27/2024: 2-1 TB (Favorite: Red Sox, Spread: -1.5, Total: 8, Favorite Moneyline: -126, Underdog Moneyline: +108)
• 9/19/2024: 2-0 TB (Favorite: Red Sox, Spread: -1.5, Total: 8, Favorite Moneyline: -112, Underdog Moneyline: -104)
• 9/18/2024: 2-1 BOS (Favorite: Rays, Spread: -1.5, Total: 7.5, Favorite Moneyline: -110, Underdog Moneyline: -106)
• 9/17/2024: 8-3 TB (Favorite: Red Sox, Spread: -1.5, Total: 8, Favorite Moneyline: -130, Underdog Moneyline: +110)
• 5/22/2024: 8-5 BOS (Favorite: Rays, Spread: -1.5, Total: 7.5, Favorite Moneyline: -144, Underdog Moneyline: +122)
• 5/21/2024: 5-2 BOS (Favorite: Rays, Spread: -1.5, Total: 8.5, Favorite Moneyline: -138, Underdog Moneyline: +118)

Sign up for FanDuel Sportsbook and FanDuel Daily Fantasy today!