Rays vs Cardinals Prediction, Odds, Moneyline, Spread & Over/Under for Aug. 24

Odds updated as of 11:11 p.m.

The Tampa Bay Rays versus the St. Louis Cardinals is on the MLB schedule for Sunday.

We've got you covered, in terms of the vital information about this game before you take a look at the MLB odds and spreads on FanDuel Sportsbook.

Rays vs Cardinals Game Info

• Tampa Bay Rays (62-67) vs. St. Louis Cardinals (64-66)
• Date: Sunday, August 24, 2025
• Time: 12:10 p.m. ET
• Venue: George M. Steinbrenner Field -- Tampa, Florida
• Coverage: FDSSUN and FDSMW

Rays vs Cardinals Odds & Moneyline

• All MLB odds, betting lines and prop bets are available on FanDuel Sportsbook.
• Moneyline: TB: (-120) | STL: (+102)
• Spread: TB: +1.5 (-192) | STL: -1.5 (+158)
• Total: 8.5 -- Over: (-122) | Under: (-100)

Rays vs Cardinals Probable Starting Pitchers

Probable Pitchers: Ryan Pepiot (Rays) - 8-10, 3.95 ERA vs Matthew Liberatore (Cardinals) - 6-10, 4.13 ERA

The probable pitchers are Ryan Pepiot (8-10) for the Rays and Matthew Liberatore (6-10) for the Cardinals. Pepiot's team is 8-18-0 against the spread this season in his starts. Pepiot's team has won 58.3% of his starts when they are favored on the moneyline (7-5). The Cardinals have gone 11-11-0 ATS in Liberatore's 22 starts that had a set spread. The Cardinals have been the moneyline underdog in nine of Liberatore's starts this season, and they went 7-2 in those games.

Rays vs Cardinals Prediction & Pick

All MLB win probability predictions and picks are according to numberFire.
Prediction: Rays win (55.7%)

Rays vs Cardinals Moneyline

• Tampa Bay is the favorite, -120 on the moneyline, while St. Louis is a +102 underdog on the road.

Rays vs Cardinals Spread

• The Cardinals are 1.5-run favorites against the spread for this matchup with the Rays. The Cardinals are +158 to cover, while the Rays are -192 to cover as a 1.5-run underdog on the runline.

Rays vs Cardinals Over/Under

• A combined run total of 8.5 has been set for Rays-Cardinals on Aug. 24, with the over at -122 and the under at -100.

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Rays vs Cardinals Betting Trends

• The Rays have been favorites in 58 games this season and have come away with the win 34 times (58.6%) in those contests.
• This season Tampa Bay has come away with a win 27 times in 47 chances when named as a favorite of at least -120 on the moneyline.
• The Rays' games have gone over the total in 53 of their 125 opportunities.
• The Rays have posted a record of 53-72-0 against the spread this season.
• The Cardinals have put together a 33-36 record in games they were the underdog on the moneyline (winning 47.8% of those games).
• St. Louis is 20-28 (winning 41.7% of its games) when it has played as a moneyline underdog of +102 or longer.
• The Cardinals have played in 125 games with a set over/under, and have combined with opponents to go over the total 65 times (65-55-5).
• The Cardinals have gone 64-61-0 ATS this season.

Rays Player Leaders

• Junior Caminero has 123 hits, which is best among Tampa Bay hitters this season, while batting .255 with 57 extra-base hits. He has an on-base percentage of .299 and a slugging percentage of .523.
• Among qualified batters in baseball, his batting average ranks 87th, his on-base percentage ranks 133rd, and he is 12th in slugging.
• Caminero has picked up at least one hit in three straight games. In his last five games he is batting .150 with a home run, three walks and two RBIs.
• Yandy Diaz has hit 21 homers this season while driving in 73 runs. He's batting .281 this season and slugging .463 with an on-base percentage of .341.
• Among qualifying batters, he is 28th in batting average, 54th in on-base percentage and 49th in slugging percentage.
• Brandon Lowe is batting .268 with a .489 slugging percentage and 63 RBI this year.
• Lowe has recorded at least one base hit in two straight games. During his last five outings he is batting .118 with a home run, three walks and two RBIs.
• Chandler Simpson has been key for Tampa Bay with 89 hits, an OBP of .340 plus a slugging percentage of .355.
• Simpson has safely hit in four straight games. During his last five outings he is hitting .273 with a double, two walks and an RBI.

Cardinals Player Leaders

• Alec Burleson is batting .285 with 20 doubles, a triple, 15 home runs and 33 walks. He's slugging .449 with an on-base percentage of .337.
• Including all qualified hitters, he is 23rd in batting average, while his on-base percentage is 60th and he is 66th in slugging.
• Willson Contreras leads his team with 114 hits. He has a batting average of .263 while slugging .463 with an on-base percentage of .345.
• Including all qualified players, he is 61st in batting average, 48th in on-base percentage and 49th in slugging percentage.
• Masyn Winn is batting .258 with 26 doubles, nine home runs and 31 walks.
• Lars Nootbaar is batting .241 with 20 doubles, 13 home runs and 50 walks.

Rays vs Cardinals Head to Head

• 8/22/2025: 10-6 TB (Favorite: Rays, Spread: -1.5, Total: 8.5, Favorite Moneyline: -138, Underdog Moneyline: +118)
• 8/21/2025: 7-4 STL (Favorite: Cardinals, Spread: -1.5, Total: 8.5, Favorite Moneyline: -118, Underdog Moneyline: -100)
• 8/8/2024: 6-4 TB (Favorite: Cardinals, Spread: -1.5, Total: 8, Favorite Moneyline: -124, Underdog Moneyline: +106)
• 8/7/2024: 5-2 STL (Favorite: Cardinals, Spread: -1.5, Total: 7.5, Favorite Moneyline: -120, Underdog Moneyline: +102)
• 8/6/2024: 4-3 STL (Favorite: Cardinals, Spread: -1.5, Total: 7.5, Favorite Moneyline: -154, Underdog Moneyline: +130)
• 8/10/2023: 5-2 STL (Favorite: Rays, Spread: -1.5, Total: 9.5, Favorite Moneyline: -210, Underdog Moneyline: +176)
• 8/9/2023: 6-4 STL (Favorite: Rays, Spread: -1.5, Total: 9, Favorite Moneyline: -158, Underdog Moneyline: +134)
• 8/8/2023: 4-2 TB (Favorite: Rays, Spread: -1.5, Total: 8.5, Favorite Moneyline: -172, Underdog Moneyline: +144)
• 6/9/2022: 2-1 TB (Favorite: Rays, Spread: -1.5, Total: 6.5, Favorite Moneyline: -168, Underdog Moneyline: +142)
• 6/8/2022: 11-3 TB (Favorite: Rays, Spread: -1.5, Total: 7.5, Favorite Moneyline: -146, Underdog Moneyline: +124)

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