Rays vs Astros Prediction, Odds, Moneyline, Spread & Over/Under for Sept. 13

Odds updated as of 8:12 p.m.

Sunday's slate in the MLB includes a matchup between the Tampa Bay Rays and the Houston Astros.

Before you do any MLB betting on this matchup at FanDuel Sportsbook, here's everything you need to know.

Rays vs Astros Game Info

• Tampa Bay Rays (88-59) vs. Houston Astros (75-73)
• Date: Sunday, September 13, 2026
• Time: 1:40 p.m. ET
• Venue: Tropicana Field -- St. Petersburg, Florida
• Coverage: Rays.TV and SCHN

Rays vs Astros Odds & Moneyline

• All MLB odds, betting lines and prop bets are available on FanDuel Sportsbook.
• Moneyline: TB: (-136) | HOU: (+116)
• Spread: TB: -1.5 (+162) | HOU: +1.5 (-196)
• Total: 7.5 -- Over: (-115) | Under: (-105)

Rays vs Astros Probable Starting Pitchers

Probable Pitchers: Freddy Peralta (Rays) - 8-11, 4.82 ERA vs Hayden Wesneski (Astros) - 5-1, 3.35 ERA

The Rays will give the nod to Freddy Peralta (8-11) against the Astros and Hayden Wesneski (5-1). Peralta and his team have a record of 15-14-0 against the spread when he starts. Peralta's team has a record of 10-7 this season when he starts and they are the favorite on the moneyline. The Astros have a 7-1-0 record against the spread in Wesneski's starts. The Astros were the underdog on the moneyline for two Wesneski starts this season -- they won both.

Rays vs Astros Prediction & Pick

All MLB win probability predictions and picks are according to numberFire.
Prediction: Rays win (57.7%)

Rays vs Astros Moneyline

• The moneyline numbers for Rays vs. Astros reveal Tampa Bay as the favorite (-136) and Houston as the underdog (+116) on the road.

Rays vs Astros Spread

• The Astros are +1.5 on the spread (-196 to cover), and Tampa Bay is +162 to cover the runline.

Rays vs Astros Over/Under

• Rays versus Astros on Sept. 13 has an over/under of 7.5 runs, with the odds on the over -115 and the under set at -105.

Bet on Tampa Bay Rays vs. Houston Astros on FanDuel today!

Rays vs Astros Betting Trends

• The Rays have been victorious in 59, or 61.5%, of the 96 contests they have been chosen as favorites in this season.
• This season Tampa Bay has come away with a win 32 times in 49 chances when named as a favorite of at least -136 on the moneyline.
• Contests with the Rays have gone over the total set by sportsbooks in 69 of 145 chances this season.
• The Rays are 79-66-0 against the spread in their 145 games that had a posted line this season.
• The Astros have been the underdog on the moneyline 78 total times this season. They've gone 40-38 in those games.
• Houston has gone 18-18 when playing as a moneyline underdog with odds of +116 or longer (50%).
• In the 148 games oddsmakers have set an over/under for the Astros, they have combined with opponents to go over the total 74 times (74-67-7).
• The Astros have covered 50% of their games this season, going 74-74-0 ATS.

Rays Player Leaders

• Junior Caminero has 157 hits, which ranks first among Tampa Bay hitters this season, while batting .279 with 62 extra-base hits. He has an on-base percentage of .365 and a slugging percentage of .534.
• Among qualifying hitters, he is 25th in batting average, his on-base percentage ranks 21st, and he is fourth in slugging.
• Yandy Diaz has a slash line of .303/.368/.467 this season and a team-best OPS of .835.
• He is sixth in batting average, 17th in on-base percentage and 34th in slugging among qualifying batters.
• Liam Hicks has 127 hits this season and a team-best OBP of .368.
• Jonathan Aranda has 19 home runs, 86 RBI and a batting average of .276 this season.

Astros Player Leaders

• Yordan Alvarez has accumulated a team-high OBP (.427) and slugging percentage (.590), and paces the Astros in hits (162, while batting .310).
• Including all qualifying hitters in the majors, his batting average puts him second, his on-base percentage is first, and he is first in slugging.
• Isaac Paredes is hitting .260 with 26 doubles, a triple, 19 home runs and 63 walks. He's slugging .426 with an on-base percentage of .359.
• He ranks 61st in batting average, 30th in on-base percentage and 69th in slugging percentage in the majors.
• Christian Walker is hitting .227 with 25 doubles, a triple, 25 home runs and 46 walks.
• Jose Altuve is batting .246 with 22 doubles, two triples, 15 home runs and 39 walks.

Rays vs Astros Head to Head

• 9/11/2026: 3-1 TB (Favorite: Rays, Spread: -1.5, Total: 7.5, Favorite Moneyline: -200, Underdog Moneyline: +168)
• 7/5/2026: 2-0 HOU (Favorite: Astros, Spread: -1.5, Total: 9, Favorite Moneyline: -116, Underdog Moneyline: -102)
• 7/4/2026: 10-8 HOU (Favorite: Astros, Spread: -1.5, Total: 7, Favorite Moneyline: -112, Underdog Moneyline: -104)
• 7/3/2026: 3-1 TB (Favorite: Astros, Spread: -1.5, Total: 9, Favorite Moneyline: -108, Underdog Moneyline: -108)
• 6/1/2025: 1-0 HOU (Favorite: Astros, Spread: -1.5, Total: 7.5, Favorite Moneyline: -166, Underdog Moneyline: +140)
• 5/31/2025: 16-3 TB (Favorite: Astros, Spread: -1.5, Total: 8.5, Favorite Moneyline: -132, Underdog Moneyline: +112)
• 5/30/2025: 2-1 HOU (Favorite: Astros, Spread: -1.5, Total: 7.5, Favorite Moneyline: -146, Underdog Moneyline: +124)
• 5/29/2025: 13-3 TB (Favorite: Astros, Spread: -1.5, Total: 8.5, Favorite Moneyline: -116, Underdog Moneyline: -102)
• 5/21/2025: 8-4 TB (Favorite: Astros, Spread: -1.5, Total: 8.5, Favorite Moneyline: -162, Underdog Moneyline: +136)
• 5/20/2025: 3-2 TB (Favorite: Rays, Spread: -1.5, Total: 9, Favorite Moneyline: -136, Underdog Moneyline: +116)

Sign up for FanDuel Sportsbook and FanDuel Daily Fantasy today!