Rams vs Bills Prediction, Odds, Picks, Best Bets for NFL Week 5 Monday Night Football

Monday's slate in the NFL includes a matchup between the Los Angeles Rams and the Buffalo Bills.

All the info you need is below, in order to make a smart bet on this game at FanDuel Sportsbook.

Rams vs Bills Prediction & Pick

All NFL win probability predictions and picks are according to numberFire.
Prediction: Rams win (60.2%)

Rams vs Bills Point Spread

The Rams are 3.5-point favorites against the Bills. The Rams are -105 to cover the spread, while the Bills are -115 to cover as a 3.5-point underdog.

Rams vs Bills Over/Under

The over/under for the Rams versus Bills matchup on Oct. 12 has been set at 54.5, with -110 odds on the over and -110 odds on the under.

Rams vs Bills Moneyline

Buffalo is a +154 underdog on the moneyline, while Los Angeles is a -184 favorite on the road.

Rams vs Bills Betting Trends

• Los Angeles has posted two wins against the spread this season.
• The Rams have two wins ATS (2-1) as a 3.5-point favorite or greater this season.
• Los Angeles has had two games (out of four) go over the total this year.
• The Bills are 3-1-0 against the spread this year.
• The Bills have seen three of their four games go over the point total.

Check out even more in-depth Rams vs. Bills analysis on FanDuel Research.

Rams vs Bills Odds & Spread

• All NFL odds, betting lines and prop bets are available on FanDuel Sportsbook.
• Moneyline: LAR: (-184) | BUF: (+154)
• Spread: LAR: -3.5 (-105) | BUF: +3.5 (-115)
• Total: 54.5 -- Over: (-110) | Under: (-110)

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