Purdue vs Michigan State College Basketball Prediction, Odds, Picks, Best Bets for Feb. 26

Big Ten play features the No. 8 Purdue Boilermakers (22-5, 12-4 Big Ten) at home against the No. 13 Michigan State Spartans (22-5, 12-4 Big Ten) on Thursday, February 26, 2026 at 8 p.m. ET.

Before you place your bet on this game at FanDuel Sportsbook, here are the NCAA basketball odds and spreads you need to know.

Purdue vs. Michigan State Game Info and Odds

• Game day: Thursday, February 26, 2026
• Game time: 8 p.m. ET
• TV channel: Peacock
• Location: West Lafayette, Indiana
• Arena: Mackey Arena

Purdue vs. Michigan State Picks and Prediction

All college basketball win probability predictions and picks are according to numberFire.
Prediction: Purdue win (62%)

Purdue is a 6.5-point favorite against Michigan State on Thursday and the over/under has been set at 143.5 points. Below are a few betting trends and insights before making an informed wager on the contest.

Sign up for FanDuel Sportsbook and FanDuel Daily Fantasy today!

Purdue vs. Michigan State: ATS Betting Stats and Trends

• Purdue has won 13 games against the spread this season, while failing to cover 14 times.
• Michigan State has won 14 games against the spread this season, while failing to cover 13 times.
• Against the spread, the Boilermakers have played worse at home, covering five times in 15 home games, and six times in nine road games.
• Against the spread, the Spartans have been better at home (8-8-0) than on the road (3-4-0).
• Purdue's record against the spread in conference games is 7-9-0.
• Michigan State's Big Ten record against the spread is 9-7-0.

Purdue vs. Michigan State: Moneyline Betting Stats

• Purdue has been the moneyline favorite in 21 games this season and has come away with the win 17 times (81%) in those contests.
• The Boilermakers have been a -319 moneyline favorite on 14 occasions this season and won every game.
• Michigan State is 1-3 in games it was listed as the moneyline underdog (winning 25% of those games).
• The Spartans have yet to play a game with moneyline odds of +255 or longer.
• Purdue has an implied victory probability of 76.1% according to the moneyline set for this matchup.

Purdue vs. Michigan State Head-to-Head Comparison

• Purdue averages 82.9 points per game (46th in college basketball) while giving up 69.3 per outing (65th in college basketball). It has a +369 scoring differential overall and outscores opponents by 13.6 points per game.
• Braden Smith's team-leading 14.9 points per game ranks 301st in the country.
• Michigan State has a +332 scoring differential, topping opponents by 12.3 points per game. It is putting up 78.4 points per game, 126th in college basketball, and is giving up 66.1 per outing to rank 19th in college basketball.
• Jeremy Fears Jr.'s 15 points per game paces Michigan State and ranks 291st in college basketball.
• The Boilermakers average 34.1 rebounds per game (76th in college basketball) while conceding 26.9 per outing to their opponents. They outrebound opponents by 7.2 boards per game.
• Trey Kaufman-Renn tops the team with nine rebounds per game (36th in college basketball play).
• The 38.3 rebounds per game the Spartans accumulate rank fourth in the country, 12.7 more than the 25.6 their opponents pull down.
• Jaxon Kohler is 26th in the country with 9.3 rebounds per game, leading the Spartans.
• Purdue records 110.1 points per 100 possessions (fourth in college basketball), while allowing 92 points per 100 possessions (106th in college basketball).
• The Spartans put up 103.5 points per 100 possessions (57th in college basketball), while conceding 87.2 points per 100 possessions (31st in college basketball).

Sign up for FanDuel Sportsbook and FanDuel Daily Fantasy today!