Purdue vs Eastern Illinois College Basketball Prediction, Odds, Picks, Best Bets for Nov. 28

The Purdue Boilermakers (6-0) will try to continue a four-game home winning streak when they host the Eastern Illinois Panthers (2-4) on November 28, 2025 at Mackey Arena.

Before you place your bet on this matchup at FanDuel Sportsbook, here are the NCAA basketball odds and spreads you need to know.

Purdue vs. Eastern Illinois Game Info and Odds

• Game day: Friday, November 28, 2025
• Game time: 12 p.m. ET
• TV channel: Big Ten Network
• Location: West Lafayette, Indiana
• Arena: Mackey Arena

Purdue vs. Eastern Illinois Picks and Prediction

All college basketball win probability predictions and picks are according to numberFire.
Prediction: Purdue win (99.2%)

Check out these betting trends and insights before you wager on Friday's Purdue-Eastern Illinois spread (Purdue -40.5) or total (141.5 points).

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Purdue vs. Eastern Illinois: ATS Betting Stats and Trends

• Purdue has won two games against the spread this season.
• Eastern Illinois is 3-2-0 ATS this season.
• The Boilermakers covered the spread in a higher percentage of their home games than away games last season. They covered 10 times in 16 opportunities when playing at home, and they covered six times in 11 opportunities in road games.
• Against the spread last year, the Panthers had better results on the road (8-8-0) than at home (4-7-0).

Purdue vs. Eastern Illinois Head-to-Head Comparison

• Purdue scored 77.3 points per game and gave up 70.4 last season, making them 82nd in the nation on offense and 126th on defense.
• Purdue grabbed 29.9 rebounds per game and gave up 28.2 boards last season, ranking 300th and 28th, respectively, in the nation.
• Last season Purdue was ranked 42nd in the nation in assists with 15.9 per game.
• Last season, Purdue was 62nd in the nation in turnovers committed (9.9 per game) and 176th in turnovers forced (11.3).
• Eastern Illinois found it difficult to score points last season, ranking 18th-worst in college basketball with 66.5 points per game. It fared better on defense, ranking 81st by surrendering 69.0 points per contest.
• Last season Eastern Illinois grabbed 31.3 boards per game (214th-ranked in college basketball) and allowed 33.2 rebounds per contest (300th-ranked).
• Eastern Illinois ranked 330th in college basketball with 11.3 dimes per contest.
• Eastern Illinois committed 11.6 turnovers per game last season (232nd-ranked in college basketball), and it forced 14.2 turnovers per contest (17th-best).

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