Pistons vs. Cavaliers Prediction, Odds, Picks, Best Bets for Feb. 27

Pistons vs. Cavaliers Game Info

• Date: Friday, February 27, 2026
• Time: 7 p.m. ET
• Venue: Little Caesars Arena -- Detroit, Michigan
• Coverage: ESPN, FDSDET, and FDSOH

Central Division foes meet when the Detroit Pistons (43-14) host the Cleveland Cavaliers (37-23) at Little Caesars Arena, beginning at 7 p.m. ET on Friday, February 27, 2026. The Pistons are 6-point favorites in the game, the third matchup between the squads this season. The matchup has an over/under set at 227.5 points.

Pistons vs. Cavaliers Odds & Spread

All NBA betting lines, odds and prop bets are from FanDuel Sportsbook.

Pistons vs. Cavaliers Prediction & Pick

All NBA win probability predictions and picks are according to numberFire.
Prediction: Pistons win (66.8%)

Pistons vs. Cavaliers Betting Trends

• The Pistons have gone 31-25-1 against the spread this season.
• The Cavaliers have 26 wins against the spread in 60 games this season.
• Games involving the Pistons have hit the over 26 times out of 60 chances this season.
• The Cavaliers have eclipsed the over/under 48.3% of the time this season (29 of 60 games with a set point total).
• Detroit has covered the spread in a lower percentage of its home games than away games. It has covered 15 times in 30 games at home, and it has covered 16 times in 27 games on the road.
• The Pistons have gone over the over/under less consistently when playing at home, hitting the over in 13 of 30 home matchups (43.3%). In away games, they have hit the over in 13 of 27 games (48.1%).
• This season, Cleveland is 13-18-0 at home against the spread (.419 winning percentage). Away, it is 13-16-0 ATS (.448).
• Looking at the over/under, Cavaliers games have finished over less frequently at home (12 of 31, 38.7%) than on the road (17 of 29, 58.6%).

Pistons Leaders

• Cade Cunningham is averaging 25.4 points, 5.7 boards and 9.8 assists. Defensively, he averages 1.5 steals (eighth in league) and 1 block.
• Jalen Duren is averaging 18.2 points, 10.6 boards and 1.7 assists. Defensively, he averages 0.9 steals and 0.7 blocked shots.
• Ausar Thompson averages 10.2 points, 5.8 boards and 2.9 assists, shooting 51.1% from the field.
• Duncan Robinson is averaging 12.4 points, 2.7 boards and 1.9 assists. At the other end, he averages 0.6 steals and 0.3 blocked shots.
• Tobias Harris is averaging 13 points, 5.2 rebounds and 2.3 assists. Defensively, he averages 0.9 steals and 0.3 blocked shots.

Cavaliers Leaders

• James Harden averages 24.5 points, 4.8 rebounds and 8.1 assists. He is also draining 42.7% of his shots from the floor and 36% from beyond the arc, with 3 triples per game.
• Per game, Evan Mobley gets the Cavaliers 17.5 points, 8.6 rebounds and 3.9 assists. He also averages 0.9 steals and 1.8 blocks (fifth in NBA).
• The Cavaliers are getting 15.1 points, 8.6 boards and 1.9 assists per game from Jarrett Allen.
• The Cavaliers get 13.5 points per game from Jaylon Tyson, plus 5.4 rebounds and 2.2 assists.
• The Cavaliers are receiving 12.2 points, 2.9 boards and 5.1 assists per game from Dennis Schroder.

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