Pistons vs. 76ers Prediction, Odds, Picks, Best Bets for Nov. 14

Pistons vs. 76ers Game Info

• Date: Friday, November 14, 2025
• Time: 7:30 p.m. ET
• Venue: Little Caesars Arena -- Detroit, Michigan
• Coverage: FDSDET and NBCS-PH

Two of the NBA's top scorers take the court when Cade Cunningham (10th, 27.5 PPG) and the Detroit Pistons (10-2) host Tyrese Maxey (third, 32.1 PPG) and the Philadelphia 76ers (7-4) on Friday, November 14, 2025 at 7:30 p.m. ET on FDSDET and NBCS-PH. The Pistons are 4.5-point favorites. The point total is set at 230.5 in the matchup.

Pistons vs. 76ers Odds & Spread

All NBA betting lines, odds and prop bets are from FanDuel Sportsbook.

Pistons vs. 76ers Prediction & Pick

All NBA win probability predictions and picks are according to numberFire.
Prediction: Pistons win (76.9%)

Pistons vs. 76ers Betting Trends

• The Pistons have covered the spread eight times this season (8-4-0).
• Against the spread, the 76ers are 7-3-1 this year.
• Pistons games have finished with a final combined score above the over/under six times out of 11 chances this season.
• 76ers games this year have hit the over seven times in 11 opportunities (63.6%).
• In home games, Detroit has a better record against the spread (5-2-0) compared to its ATS record in road games (3-2-0).
• The Pistons have eclipsed the over/under more often at home, hitting the over in five of seven home matchups (71.4%). On the road, they have hit the over in one of five games (20%).
• Philadelphia has performed better against the spread at home (4-1-1) than on the road (3-2-0) this year.
• In 2025-26 a lower percentage of the 76ers' games have finished above the over/under at home (50%, three of six) compared to away (80%, four of five).

Pistons Leaders

• Cunningham is averaging 27.5 points, 9.9 assists and 5.4 boards.
• Jalen Duren averages 19.4 points, 12 boards and 1.6 assists.
• Duncan Robinson is averaging 12.3 points, 2.6 boards and 1.7 assists. At the other end, he averages 0.7 steals and 0.3 blocked shots.
• Ron Holland II averages 9.3 points, 3.8 boards and 1.8 assists, shooting 40.4% from the field and 31% from beyond the arc, with 1.1 made 3-pointers per game.
• Isaiah Stewart is averaging 10.7 points, 6.7 rebounds and 1.6 assists. Defensively, he averages 0.2 steals and 2.1 blocked shots (fourth in league).

76ers Leaders

• Maxey's numbers on the season are 32.1 points, 4.9 boards and 8.3 assists per game. He is also sinking 45.8% of his shots from the field and 44.4% from 3-point range, with an average of 4 triples (second in NBA).
• VJ Edgecombe averages 15.4 points, 5.5 boards and 4.3 assists. He is also making 40.9% of his shots from the floor and 36.2% from beyond the arc, with 1.9 triples per game.
• The 76ers receive 18 points per game from Kelly Oubre Jr., plus 5.5 rebounds and 1.4 assists.
• Per game, Quentin Grimes gives the 76ers 17.3 points, 4.3 boards and 4.4 assists, plus 0.9 steals and 0.5 blocks.
• Andre Drummond averages 7.6 points, 8.6 rebounds and 0.7 assists. He is making 56.6% of his shots from the field.

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