Pirates vs Red Sox Prediction, Odds, Moneyline, Spread & Over/Under for Aug. 29

Odds updated as of 7:14 a.m.

The Pittsburgh Pirates versus the Boston Red Sox is on the MLB schedule for Friday.

Before checking out the MLB betting lines on FanDuel Sportsbook, we've got you covered, in terms of the vital info about this matchup.

Pirates vs Red Sox Game Info

• Pittsburgh Pirates (59-76) vs. Boston Red Sox (75-60)
• Date: Friday, August 29, 2025
• Time: 7:10 p.m. ET
• Venue: Fenway Park -- Boston, Massachusetts
• Coverage: MLB Network, NESN, and SportsNet PT

Pirates vs Red Sox Odds & Moneyline

• All MLB odds, betting lines and prop bets are available on FanDuel Sportsbook.
• Moneyline: PIT: (-110) | BOS: (-106)
• Spread: PIT: -1.5 (+152) | BOS: +1.5 (-184)
• Total: 8 -- Over: (-104) | Under: (-118)

Pirates vs Red Sox Probable Starting Pitchers

Probable Pitchers: Paul Skenes (Pirates) - 8-9, 2.07 ERA vs Payton Tolle (Red Sox) - 0-0, 0.00 ERA

This contest's pitching matchup is set, as the Pirates will send Paul Skenes (8-9) to the mound, while Payton Tolle will get the nod for the Red Sox. Skenes and his team have a record of 13-14-0 against the spread when he starts. Skenes' team has a record of 11-7 this season when he starts and they are the favorite on the moneyline. Tolle and his team were moneyline underdogs each game he pitched a season ago.

Pirates vs Red Sox Prediction & Pick

All MLB win probability predictions and picks are according to numberFire.
Prediction: Red Sox win (59.4%)

Pirates vs Red Sox Moneyline

• Looking at the moneyline for Pirates-Red Sox, Pittsburgh is the favorite at -110, and Boston is -106 playing at home.

Pirates vs Red Sox Spread

• The Pirates are 1.5-run road favorites on the runline against the Red Sox. The Pirates are +152 to cover, and the Red Sox are -184.

Pirates vs Red Sox Over/Under

• The over/under for the Pirates versus Red Sox contest on Aug. 29 has been set at 8, with -104 odds on the over and -118 odds on the under.

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Pirates vs Red Sox Betting Trends

• The Pirates have been favorites in 36 games this season and have come away with the win 19 times (52.8%) in those contests.
• This season Pittsburgh has been victorious 19 times in 36 chances when named as a favorite of at least -110 on the moneyline.
• The Pirates and their opponents have gone over in 50 of their 127 games with a total set by sportsbooks this season.
• The Pirates have an against the spread record of 69-58-0 in 127 games with a line this season.
• The Red Sox have compiled a 22-25 record in games they were listed as the moneyline underdog (winning 46.8% of those games).
• Boston has a record of 22-24 in games it has played as a moneyline underdog with odds of -106 or longer (47.8%).
• The Red Sox have had an over/under set by bookmakers 134 times, and have combined with opponents to go over the total in 64 of those games (64-65-5).
• The Red Sox have collected a 73-61-0 record ATS this season.

Pirates Player Leaders

• Bryan Reynolds leads Pittsburgh with 122 hits and a team-best slugging percentage of .409. He's batting .244 with an on-base percentage of .305.
• Among all qualified hitters, he is 110th in batting average, his on-base percentage ranks 120th, and he is 97th in slugging.
• Oneil Cruz is batting .202 with 17 doubles, two triples, 18 home runs and 57 walks. He's slugging .389 with an on-base percentage of .304.
• He is 154th in batting average, 123rd in on-base percentage and 119th in slugging in the major leagues.
• Andrew McCutchen leads Pittsburgh with an OBP of .332 this season while batting .239 with 55 walks and 42 runs scored.
• Isiah Kiner-Falefa has been key for Pittsburgh with 105 hits, an OBP of .304 plus a slugging percentage of .337.

Red Sox Player Leaders

• Jarren Duran has racked up an on-base percentage of .334, a slugging percentage of .444, and has 134 hits, all club-highs for the Red Sox (while batting .258).
• Including all the qualifying hitters in the majors, his batting average is 78th, his on-base percentage ranks 68th, and he is 70th in slugging.
• Trevor Story is hitting .257 with 22 doubles, 22 home runs and 28 walks. He's slugging .432 with an on-base percentage of .304.
• He is currently 82nd in batting average, 123rd in on-base percentage and 78th in slugging percentage among all qualified hitters.
• Ceddanne Rafaela has 29 doubles, three triples, 15 home runs and 22 walks while hitting .249.
• Alex Bregman is hitting .294 with 24 doubles, 16 home runs and 39 walks.

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