Pirates vs Nationals Prediction, Odds, Moneyline, Spread & Over/Under for April 16

Odds updated as of 6:12 p.m.

The MLB's Wednesday slate includes the Pittsburgh Pirates taking on the Washington Nationals.

We've got you covered, in terms of the vital information regarding this game before you take a look at the MLB odds and spreads on FanDuel Sportsbook.

Pirates vs Nationals Game Info

• Pittsburgh Pirates (6-12) vs. Washington Nationals (7-10)
• Date: Wednesday, April 16, 2025
• Time: 6:40 p.m. ET
• Venue: PNC Park -- Pittsburgh, Pennsylvania
• Coverage: SportsNet PT and MASN

Pirates vs Nationals Odds & Moneyline

• All MLB odds, betting lines and prop bets are available on FanDuel Sportsbook.
• Moneyline: PIT: (-112) | WSH: (-104)
• Spread: PIT: +1.5 (-184) | WSH: -1.5 (+152)
• Total: 8 -- Over: (-115) | Under: (-105)

Pirates vs Nationals Probable Starting Pitchers

Probable Pitchers: Bailey Falter (Pirates) - 0-2, 7.20 ERA vs Mitchell Parker (Nationals) - 2-0, 1.96 ERA

The probable pitchers are Bailey Falter (0-2) for the Pirates and Mitchell Parker (2-0) for the Nationals. Falter's team has not covered in any of his three starts with a spread this season. Falter's team lost his only start as a favorite this season. The Nationals covered all of Parker's three starts with a set spread. The Nationals were the underdog on the moneyline for two Parker starts this season -- they won both.

Pirates vs Nationals Prediction & Pick

All MLB win probability predictions and picks are according to numberFire.
Prediction: Pirates win (52.6%)

Pirates vs Nationals Moneyline

• The Pirates vs Nationals moneyline has Pittsburgh as a -112 favorite, while Washington is a -104 underdog on the road.

Pirates vs Nationals Spread

• The Nationals are 1.5-run favorites against the spread for this matchup with the Pirates. The Nationals are +152 to cover, while the Pirates are -184 to cover as a 1.5-run underdog on the runline.

Pirates vs Nationals Over/Under

• An over/under of 8 has been set for Pirates-Nationals on April 16, with the over being -115 and the under -105.

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Pirates vs Nationals Betting Trends

• The Pirates have come away with three wins in the seven contests they have been listed as the favorites in this season.
• This year Pittsburgh has won three of seven games when listed as at least -112 on the moneyline.
• The Pirates and their opponents have gone over the total this season in eight of their 18 opportunities.
• The Pirates are 5-13-0 against the spread in their 18 games with a line set by sportsbooks this season.
• The Nationals have been the underdog on the moneyline 14 total times this season. They've finished 6-8 in those games.
• When playing as a moneyline underdog with odds of -104 or longer, Washington has a 6-8 record (winning 42.9% of its games).
• The Nationals have combined with opponents to go over the total 11 times this season for an 11-6-0 record against the over/under.
• The Nationals have a 9-8-0 record against the spread this season.

Pirates Player Leaders

• Ke'Bryan Hayes has a double, a triple, a home run and seven walks while hitting .217. He has an on-base percentage of .299 and a slugging percentage of .317.
• Among all qualified hitters in the majors, he is 108th in batting average, 115th in on-base percentage, and 134th in slugging.
• Oneil Cruz has 10 hits and an OBP of .333, both of which lead the Pirates this season. He's batting .200 and slugging .360.
• Among all qualifying batters, he is 130th in batting average, 71st in on-base percentage and 116th in slugging percentage.
• Isiah Kiner-Falefa has collected 14 base hits, an OBP of .323 and a slugging percentage of .304 this season.
• Andrew McCutchen is batting .270 with a .357 OBP and five RBI for Pittsburgh this season.
• McCutchen has hit safely in two games in a row. During his last five outings he is hitting .143 with two walks and an RBI.

Nationals Player Leaders

• James Wood has accumulated 15 hits, a team-best for the Nationals. He's batting .242 and slugging .581 with an on-base percentage of .365.
• Including all qualifying hitters, he ranks 85th in batting average, while his on-base percentage ranks 46th and he is 14th in slugging.
• Keibert Ruiz paces his team with a .394 OBP, and has a club-best .467 slugging percentage. He has a batting average of .333.
• Including all qualified players, his batting average places him ninth, his on-base percentage ranks 22nd, and he is 56th in slugging.
• Nate Lowe has four doubles, three home runs and eight walks while hitting .267.
• Alex Call is hitting .324 with two doubles, a triple and 10 walks.

Pirates vs Nationals Head to Head

• 4/15/2025: 3-0 WSH (Favorite: Pirates, Spread: -1.5, Total: 8.5, Favorite Moneyline: -124, Underdog Moneyline: +106)
• 4/14/2025: 10-3 PIT (Favorite: Pirates, Spread: -1.5, Total: 7.5, Favorite Moneyline: -198, Underdog Moneyline: +166)
• 9/8/2024: 7-3 PIT (Favorite: Pirates, Spread: -1.5, Total: 8.5, Favorite Moneyline: -162, Underdog Moneyline: +136)
• 9/7/2024: 8-6 WSH (Favorite: Pirates, Spread: -1.5, Total: 7.5, Favorite Moneyline: -144, Underdog Moneyline: +122)
• 9/7/2024: 5-3 WSH (Favorite: Pirates, Spread: -1.5, Total: 8.5, Favorite Moneyline: -124, Underdog Moneyline: +106)
• 9/5/2024: 9-4 PIT (Favorite: Pirates, Spread: -1.5, Total: 8, Favorite Moneyline: -120, Underdog Moneyline: +102)
• 4/3/2024: 5-3 WSH (Favorite: Pirates, Spread: -1.5, Total: 8.5, Favorite Moneyline: -146, Underdog Moneyline: +124)
• 4/1/2024: 8-4 PIT (Favorite: Nationals, Spread: -1.5, Total: 8.5, Favorite Moneyline: -110, Underdog Moneyline: -106)
• 9/14/2023: 2-0 PIT (Favorite: Pirates, Spread: -1.5, Total: 8.5, Favorite Moneyline: -166, Underdog Moneyline: +140)
• 9/13/2023: 7-6 PIT (Favorite: Pirates, Spread: -1.5, Total: 9.5, Favorite Moneyline: -146, Underdog Moneyline: +124)

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