Pirates vs Cubs Prediction, Odds, Moneyline, Spread & Over/Under for May 1

Odds updated as of 1:11 a.m.

The Thursday schedule in MLB includes a matchup between the Pittsburgh Pirates and the Chicago Cubs.

Here's what you need to know before checking out today's MLB odds and spreads on FanDuel Sportsbook.

Pirates vs Cubs Game Info

• Pittsburgh Pirates (12-19) vs. Chicago Cubs (18-13)
• Date: Thursday, May 1, 2025
• Time: 12:35 p.m. ET
• Venue: PNC Park -- Pittsburgh, Pennsylvania
• Coverage: SportsNet PT and MARQ

Pirates vs Cubs Odds & Moneyline

• All MLB odds, betting lines and prop bets are available on FanDuel Sportsbook.
• Moneyline: PIT: (-152) | CHC: (+128)
• Spread: PIT: -1.5 (+142) | CHC: +1.5 (-172)
• Total: 7.5 -- Over: (-115) | Under: (-105)

Pirates vs Cubs Probable Starting Pitchers

Probable Pitchers: Paul Skenes (Pirates) - 3-2, 2.39 ERA vs Colin Rea (Cubs) - 1-0, 0.96 ERA

The probable pitchers are Paul Skenes (3-2) for the Pirates and Colin Rea (1-0) for the Cubs. Skenes and his team are 3-3-0 ATS this season when he starts. When Skenes starts a game and his team is the favorite on the moneyline, they have a record of 2-3. Rea has started two games with set spreads, and the Cubs covered in both chances. The Cubs were the moneyline underdog for two Rea starts this season -- they won both.

Pirates vs Cubs Prediction & Pick

All MLB win probability predictions and picks are according to numberFire.
Prediction: Pirates win (56.7%)

Pirates vs Cubs Moneyline

• Pittsburgh is a -152 favorite on the moneyline, while Chicago is a +128 underdog on the road.

Pirates vs Cubs Spread

• The Cubs are +1.5 on the spread (-172 to cover), and Pittsburgh is +142 to cover the runline.

Pirates vs Cubs Over/Under

• An over/under of 7.5 has been set for Pirates-Cubs on May 1, with the over being -115 and the under -105.

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Pirates vs Cubs Betting Trends

• The Pirates have been chosen as favorites in 11 games this year and have walked away with the win five times (45.5%) in those games.
• Pittsburgh has been listed as a favorite of -152 or more on two occasions this season and split those games.
• The Pirates and their opponents have gone over the total this season in 14 of their 31 opportunities.
• The Pirates are 12-19-0 against the spread in their 31 games with a line set by sportsbooks this season.
• The Cubs have won seven of the 14 games they were the underdog on the moneyline this season (50%).
• Chicago has a 2-1 record (winning 66.7% of its games) when playing as a moneyline underdog of +128 or longer.
• The Cubs have had an over/under set by bookmakers 29 times, and have combined with opponents to go over the total in 19 of those games (19-9-1).
• The Cubs have covered 51.7% of their games this season, going 15-14-0 ATS.

Pirates Player Leaders

• Oneil Cruz leads Pittsburgh with 25 hits and an OBP of .367 this season. He has a .253 batting average and a slugging percentage of .535.
• He ranks 75th in batting average, 39th in on-base percentage, and 19th in slugging among all qualified hitters in baseball.
• Andrew McCutchen is hitting .277 with six doubles, three home runs and 12 walks, while slugging .458 with an on-base percentage of .368.
• McCutchen takes a three-game streak with at least one hit into this one. During his last five outings he is hitting .368 with two doubles, a home run, two walks and three RBI.
• Isiah Kiner-Falefa is batting .280 with a .330 slugging percentage and seven RBI this year.
• Enmanuel Valdez has two home runs, 11 RBI and a batting average of .227 this season.
• Valdez heads into this matchup on a two-game hitting streak. In his last five games he is hitting .250 with a home run, a walk and two RBI.

Cubs Player Leaders

• Kyle Tucker has put up an on-base percentage of .386, a team-high for the Cubs. He's batting .279 and slugging .549.
• Including all qualified hitters in the big leagues, he ranks 42nd in batting average, 23rd in on-base percentage and 12th in slugging percentage.
• Pete Crow-Armstrong is batting .275 with 10 doubles, a triple, six home runs and six walks. He's slugging .525 with an on-base percentage of .315.
• Including all qualified hitters, his batting average places him 47th, his on-base percentage ranks 90th, and he is 23rd in slugging.
• Carson Kelly has a double, a triple, seven home runs and 15 walks while hitting .360.
• Ian Happ's .371 slugging percentage leads his team.

Pirates vs Cubs Head to Head

• 4/30/2025: 4-3 PIT (Favorite: Cubs, Spread: -1.5, Total: 8.5, Favorite Moneyline: -174, Underdog Moneyline: +146)
• 4/29/2025: 9-0 CHC (Favorite: Cubs, Spread: -1.5, Total: 8.5, Favorite Moneyline: -148, Underdog Moneyline: +126)
• 9/4/2024: 12-0 CHC (Favorite: Cubs, Spread: -1.5, Total: 8, Favorite Moneyline: -210, Underdog Moneyline: +176)
• 9/3/2024: 5-0 PIT (Favorite: Pirates, Spread: -1.5, Total: 7.5, Favorite Moneyline: -122, Underdog Moneyline: +104)
• 9/2/2024: 5-3 PIT (Favorite: Cubs, Spread: -1.5, Total: 7.5, Favorite Moneyline: -148, Underdog Moneyline: +126)
• 8/28/2024: 14-10 CHC (Favorite: Pirates, Spread: -1.5, Total: 8.5, Favorite Moneyline: -172, Underdog Moneyline: +144)
• 8/27/2024: 9-5 CHC (Favorite: Cubs, Spread: -1.5, Total: 7.5, Favorite Moneyline: -124, Underdog Moneyline: +106)
• 8/26/2024: 18-8 CHC (Favorite: Pirates, Spread: -1.5, Total: 8.5, Favorite Moneyline: -118, Underdog Moneyline: -100)
• 5/19/2024: 3-2 PIT (Favorite: Cubs, Spread: -1.5, Total: 7.5, Favorite Moneyline: -130, Underdog Moneyline: +110)
• 5/18/2024: 1-0 CHC (Favorite: Cubs, Spread: -1.5, Total: 8.5, Favorite Moneyline: -205, Underdog Moneyline: +172)

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