Phillies vs Giants Prediction, Odds, Moneyline, Spread & Over/Under for April 16

Odds updated as of 6:11 p.m.

The Philadelphia Phillies versus the San Francisco Giants is on the MLB schedule for Wednesday.

All the info you need to make smart bets on this matchup at FanDuel Sportsbook can be found below. Check out all of the latest MLB betting lines here.

Phillies vs Giants Game Info

• Philadelphia Phillies (10-7) vs. San Francisco Giants (12-5)
• Date: Wednesday, April 16, 2025
• Time: 6:45 p.m. ET
• Venue: Citizens Bank Park -- Philadelphia, Pennsylvania
• Coverage: NBCS-PH and NBCS-BA

Phillies vs Giants Odds & Moneyline

• All MLB odds, betting lines and prop bets are available on FanDuel Sportsbook.
• Moneyline: PHI: (-148) | SF: (+126)
• Spread: PHI: -1.5 (+140) | SF: +1.5 (-170)
• Total: 7.5 -- Over: (-120) | Under: (-102)

Phillies vs Giants Probable Starting Pitchers

Probable Pitchers: Aaron Nola (Phillies) - 0-3, 5.51 ERA vs Robbie Ray (Giants) - 3-0, 2.93 ERA

The Phillies will give the ball to Aaron Nola (0-3, 5.51 ERA), who is eyeing win No. 1 on the season, and the Giants will counter with Robbie Ray (3-0, 2.93 ERA). Nola's team has not covered in any of his three starts with a spread this season. Nola has started three games with his team as the moneyline favorite, and has been upset each time. The Giants covered all of the three games Ray has started that had a spread set by oddsmakers. The Giants were the moneyline underdog for one Ray start this season -- they won.

Phillies vs Giants Prediction & Pick

All MLB win probability predictions and picks are according to numberFire.
Prediction: Phillies win (66.6%)

Phillies vs Giants Moneyline

• The moneyline numbers for Phillies vs. Giants reveal Philadelphia as the favorite (-148) and San Francisco as the underdog (+126) on the road.

Phillies vs Giants Spread

• The Giants are at +1.5 on the runline against the Phillies. The Giants are -170 to cover the spread, and the Phillies are +140.

Phillies vs Giants Over/Under

• Phillies versus Giants on April 16 has an over/under of 7.5 runs, with the odds on the over -120 and the under set at -102.

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Phillies vs Giants Betting Trends

• The Phillies have been chosen as favorites in 12 games this year and have walked away with the win seven times (58.3%) in those games.
• Philadelphia has a record of 7-1 in contests when sportsbooks favor them by -148 or more on the moneyline.
• Contests with the Phillies have gone over the total set by oddsmakers in six of 17 chances this season.
• The Phillies have posted a record of 10-7-0 against the spread this season.
• The Giants have won five of the eight games they were listed as the moneyline underdog this season (62.5%).
• San Francisco has played as a moneyline underdog of +126 or longer in just two games this season, which it split 1-1.
• The Giants have played in 17 games with an over/under set, and have combined with their opponents to go over the total 12 times (12-5-0).
• The Giants have an 11-6-0 record against the spread this season (covering 64.7% of the time).

Phillies Player Leaders

• Kyle Schwarber leads Philadelphia with 16 hits and an OBP of .421 this season. He has a .267 batting average and a slugging percentage of .617.
• Among qualifying hitters in the majors, he is 64th in batting average, 13th in on-base percentage, and 11th in slugging.
• Nick Castellanos has hit three homers this season while driving in 11 runs. He's batting .306 this season and slugging .532 with an on-base percentage of .358.
• Among all qualifying players, he is 30th in batting average, 54th in on-base percentage and 28th in slugging percentage.
• Castellanos takes a two-game streak with at least one hit into this matchup. In his last five games he is batting .389 with two doubles, a home run, a walk and four RBI.
• Bryce Harper is batting .250 with a .422 slugging percentage and seven RBI this year.
• Harper has picked up a hit in four games in a row. In his last five games he is batting .211 with a home run, two walks and two RBI.
• Bryson Stott has one home run, six RBI and a batting average of .268 this season.
• Stott takes a three-game hitting streak into this game. During his last five outings he is batting .250 with a double, a triple, three walks and an RBI.

Giants Player Leaders

• Jung Hoo Lee has a team-best slugging percentage (.651) while leading the Giants in hits (21). He's batting .333 and with an on-base percentage of .400.
• Including all qualifying hitters in MLB, he is ninth in batting average, 20th in on-base percentage and sixth in slugging percentage.
• Wilmer Flores is batting .242 with six home runs and two walks. He's slugging .532 with an on-base percentage of .277.
• Including all qualifying hitters, he is 85th in batting average, 128th in on-base percentage and 28th in slugging percentage.
• Mike Yastrzemski a has .421 on-base percentage to pace the Giants.
• Matt Chapman is batting .203 with three doubles, two home runs and 15 walks.

Phillies vs Giants Head to Head

• 4/15/2025: 6-4 PHI (Favorite: Phillies, Spread: -1.5, Total: 8, Favorite Moneyline: -162, Underdog Moneyline: +136)
• 4/14/2025: 10-4 SF (Favorite: Phillies, Spread: -1.5, Total: 9, Favorite Moneyline: -112, Underdog Moneyline: -104)
• 5/29/2024: 6-1 PHI (Favorite: Phillies, Spread: -1.5, Total: 7.5, Favorite Moneyline: -126, Underdog Moneyline: +108)
• 5/28/2024: 1-0 SF (Favorite: Phillies, Spread: -1.5, Total: 7, Favorite Moneyline: -196, Underdog Moneyline: +164)
• 5/27/2024: 8-4 SF (Favorite: Giants, Spread: -1.5, Total: 8, Favorite Moneyline: -134, Underdog Moneyline: +114)
• 5/6/2024: 6-1 PHI (Favorite: Phillies, Spread: -1.5, Total: 7.5, Favorite Moneyline: -250, Underdog Moneyline: +205)
• 5/5/2024: 5-4 PHI (Favorite: Giants, Spread: -1.5, Total: 8.5, Favorite Moneyline: -112, Underdog Moneyline: -104)
• 5/3/2024: 4-3 PHI (Favorite: Phillies, Spread: -1.5, Total: 7.5, Favorite Moneyline: -174, Underdog Moneyline: +146)
• 8/23/2023: 8-6 SF (Favorite: Phillies, Spread: -1.5, Total: 9, Favorite Moneyline: -138, Underdog Moneyline: +118)
• 8/22/2023: 4-3 PHI (Favorite: Phillies, Spread: -1.5, Total: 9, Favorite Moneyline: -130, Underdog Moneyline: +110)

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