Phillies vs Cubs Prediction, Odds, Moneyline, Spread & Over/Under for April 26

Odds updated as of 2:11 a.m.

The MLB schedule on Saturday includes the Philadelphia Phillies taking on the Chicago Cubs.

We've got you covered, in terms of the most important information about this game before you take a look at the MLB odds and spreads on FanDuel Sportsbook.

Phillies vs Cubs Game Info

• Philadelphia Phillies (13-13) vs. Chicago Cubs (17-10)
• Date: Saturday, April 26, 2025
• Time: 4:05 p.m. ET
• Venue: Wrigley Field -- Chicago, Illinois
• Coverage: FOX

Phillies vs Cubs Odds & Moneyline

• All MLB odds, betting lines and prop bets are available on FanDuel Sportsbook.
• Moneyline: PHI: (-116) | CHC: (-102)
• Spread: PHI: -1.5 (+152) | CHC: +1.5 (-184)
• Total: 7 -- Over: (-105) | Under: (-115)

Phillies vs Cubs Probable Starting Pitchers

Probable Pitchers: Jesús Luzardo (Phillies) - 2-0, 2.08 ERA vs Ben Brown (Cubs) - 2-1, 4.57 ERA

This contest's pitching matchup is set, as the Phillies will send Jesus Luzardo (2-0) to the mound, while Ben Brown (2-1) will get the nod for the Cubs. Luzardo's team is 3-2-0 against the spread in his starts this season. Luzardo's team has been victorious in 66.7% of the games he's started as the moneyline favorite with a record of 2-1. When Brown starts, the Cubs are 3-1-0 against the spread. The Cubs were the underdog on the moneyline for one Brown start this season -- they won.

Phillies vs Cubs Prediction & Pick

All MLB win probability predictions and picks are according to numberFire.
Prediction: Cubs win (54.2%)

Phillies vs Cubs Moneyline

• Chicago is a -102 underdog on the moneyline, while Philadelphia is a -116 favorite on the road.

Phillies vs Cubs Spread

• The Phillies are at the Cubs and are favored by 1.5 runs on the spread. The Phillies are +152 to cover the runline, with the Cubs being -184.

Phillies vs Cubs Over/Under

• The over/under for Phillies-Cubs on April 26 is 7. The over is -105, and the under is -115.

Bet on Philadelphia Phillies vs. Chicago Cubs on FanDuel today!

Phillies vs Cubs Betting Trends

• The Phillies have been victorious in 10, or 52.6%, of the 19 contests they have been chosen as favorites in this season.
• This year Philadelphia has won 10 of 18 games when listed as at least -116 on the moneyline.
• The Phillies and their opponents have gone over the total this season in 12 of their 25 opportunities.
• The Phillies have posted a record of 13-12-0 against the spread this season.
• The Cubs have been the underdog on the moneyline 13 total times this season. They've gone 7-6 in those games.
• In games it has played as a moneyline underdog with odds of -102 or longer, Chicago has gone 6-5 (54.5%).
• The Cubs have combined with opponents to go over the total 17 times this season for a 17-7-1 record against the over/under.
• The Cubs have covered 56% of their games this season, going 14-11-0 against the spread.

Phillies Player Leaders

• Kyle Schwarber leads Philadelphia with 23 hits and an OBP of .405 this season. He has a .250 batting average and a slugging percentage of .511.
• Among all qualifying hitters, he is 76th in batting average, his on-base percentage ranks 13th, and he is 27th in slugging.
• Bryce Harper is batting .240 with four doubles, five home runs and 21 walks, while slugging .438 with an on-base percentage of .376.
• He ranks 90th in batting average, 31st in on-base percentage and 57th in slugging in the majors.
• Bryson Stott has 25 hits this season and has a slash line of .284/.354/.420.
• Nicholas Alexander Castellanos leads Philadelphia with a slugging percentage of .447, fueled by 10 extra-base hits.
• Castellanos takes a two-game hitting streak into this game. In his last five games he is hitting .158 with a double, two walks and two RBI.

Cubs Player Leaders

• Kyle Tucker has an on-base percentage of .414, a slugging percentage of .617, and has 33 hits, all club-bests for the Cubs (while batting .308).
• Including all the qualified hitters in the majors, his batting average is 21st, his on-base percentage ranks seventh, and he is sixth in slugging.
• Pete Crow-Armstrong has nine doubles, a triple, five home runs and six walks while batting .295. He's slugging .543 with an on-base percentage of .339.
• He is currently 29th in batting average, 67th in on-base percentage and 17th in slugging percentage among all qualifying hitters.
• Carson Kelly is batting .341 with a double, a triple, six home runs and 15 walks.
• Ian Happ has seven doubles, two home runs and 15 walks while batting .274.

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