Patriots vs Giants Prediction, Odds, Picks, Best Bets for NFL Week 13 Monday Night Football

On Monday in the NFL, the New England Patriots are playing the New York Giants.

We've got you covered, in terms of the vital information regarding NFL betting lines, before you make your wager on FanDuel Sportsbook.

Patriots vs Giants Prediction & Pick

All NFL win probability predictions and picks are according to numberFire.
Prediction: Patriots win (83.4%)

Patriots vs Giants Point Spread

The Patriots are 7.5-point favorites against the Giants. The Patriots are -102 to cover the spread, while the Giants are -120 to cover as a 7.5-point underdog.

Patriots vs Giants Over/Under

The over/under for Patriots-Giants on Dec. 1 is 46.5. The over is -110, and the under is -110.

Patriots vs Giants Moneyline

New England is a -391 favorite on the moneyline, while New York is a +310 underdog on the road.

Patriots vs Giants Betting Trends

• Against the spread, New England is 8-4-0 this year.
• The Patriots have one win ATS (1-1) as a 7.5-point favorite or greater this year.
• Out of 12 Patriots games so far this season, six have hit the over.
• The Giants are 7-5-0 against the spread this season.
• New York is 4-1 as 7.5-point or bigger underdogs in 2025.
• The Giants have played 12 games this season, and seven of them have hit the over.

Check out even more in-depth Patriots vs. Giants analysis on FanDuel Research.

Patriots vs Giants Odds & Spread

• All NFL odds, betting lines and prop bets are available on FanDuel Sportsbook.
• Moneyline: NE: (-391) | NYG: (+310)
• Spread: NE: -7.5 (-102) | NYG: +7.5 (-120)
• Total: 46.5 -- Over: (-110) | Under: (-110)

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