Panthers vs Sabres NHL Prediction, Odds, Picks, Best Bets for Feb. 27

The Florida Panthers are among the NHL squads playing on Friday, versus the Buffalo Sabres.

Before you make your wager on FanDuel Sportsbook, we've got you covered with all the latest NHL betting insights.

Panthers vs Sabres Game Info

• Florida Panthers (30-25-3) vs. Buffalo Sabres (33-19-6)
• Date: Friday, February 27, 2026
• Time: 7 p.m. ET
• Venue: Amerant Bank Arena -- Sunrise, Florida
• Coverage: ESPN+

Panthers vs Sabres Odds

All NHL odds, betting lines and prop bets are available on FanDuel Sportsbook.

Panthers vs Sabres Prediction & Pick

All NHL win probability predictions and picks are according to numberFire.

• Prediction: Sabres win (52.9%)

Panthers vs Sabres Puck Line

• The Sabres are underdogs by 1.5 goals. The Sabres are -265 to cover the spread, and the Panthers are +210.

Panthers vs Sabres Over/Under

• The over/under for the Panthers versus Sabres game on Feb. 27 has been set at 6.5, with +102 odds on the over and -124 odds on the under.

Panthers vs Sabres Moneyline

• Looking at the moneyline for Sabres-Panthers, Buffalo is the underdog at -105, and Florida is -114 playing at home.

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