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Panthers vs Sabres NHL Prediction, Odds, Picks, Best Bets for Oct. 18

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Panthers vs Sabres NHL Prediction, Odds, Picks, Best Bets for Oct. 18

In NHL action on Saturday, the Florida Panthers play the Buffalo Sabres.

Before you make your wager on FanDuel Sportsbook, we've got you covered, in terms of the vital information regarding today's NHL betting odds.

Panthers vs Sabres Game Info

  • Florida Panthers (3-3) vs. Buffalo Sabres (1-3)
  • Date: Saturday, October 18, 2025
  • Time: 1 p.m. ET
  • Venue: KeyBank Center -- Buffalo, New York
  • Coverage: ESPN+

Panthers vs Sabres Odds

All NHL odds, betting lines and prop bets are available on FanDuel Sportsbook.

Favorite
Underdog
Total
Puck Line
Panthers (-140)Sabres (+116)5.5Panthers (-1.5)

Panthers vs Sabres Prediction & Pick

All NHL win probability predictions and picks are according to numberFire.

  • Prediction: Panthers win (54.8%)

Panthers vs Sabres Puck Line

  • The Panthers are favored by 1.5 goals (+180 to cover). Buffalo, the underdog, is -225.

Panthers vs Sabres Over/Under

  • Panthers versus Sabres, on Oct. 18, has an over/under of 5.5, with the over being -138 and the under +112.

Panthers vs Sabres Moneyline

  • The moneyline numbers for Panthers vs. Sabres reveal Florida as the favorite (-140) and Buffalo as the underdog (+116) despite being the home team.

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