Panthers vs Flames NHL Prediction, Odds, Picks, Best Bets for Nov. 28

The Florida Panthers are among the NHL teams busy on Friday, up against the Calgary Flames.

We've got you covered, in terms of the vital information regarding NHL betting lines, before you make your wager on FanDuel Sportsbook.

Panthers vs Flames Game Info

• Florida Panthers (12-10-1) vs. Calgary Flames (8-14-3)
• Date: Friday, November 28, 2025
• Time: 4 p.m. ET
• Venue: Amerant Bank Arena -- Sunrise, Florida
• Coverage: ESPN+

Panthers vs Flames Odds

All NHL odds, betting lines and prop bets are available on FanDuel Sportsbook.

Panthers vs Flames Prediction & Pick

All NHL win probability predictions and picks are according to numberFire.

• Prediction: Panthers win (66.1%)

Panthers vs Flames Puck Line

• The Flames are 1.5-goal underdogs against the Panthers. The Flames are -162 to cover the spread, and the Panthers are +132.

Panthers vs Flames Over/Under

• Panthers versus Flames, on Nov. 28, has an over/under of 5.5, with the over being -115 and the under -105.

Panthers vs Flames Moneyline

• Looking at the moneyline for Panthers-Flames, Florida is the favorite at -194, and Calgary is +160 playing on the road.

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