Padres vs White Sox Prediction, Odds, Moneyline, Spread & Over/Under for Sept. 22

Odds updated as of 4:11 p.m.

In MLB action on Sunday, the San Diego Padres take on the Chicago White Sox.

Before checking out the MLB betting lines on FanDuel Sportsbook, we've got you covered, in terms of the most important information regarding this game.

Padres vs White Sox Game Info

• San Diego Padres (89-66) vs. Chicago White Sox (36-119)
• Date: Sunday, September 22, 2024
• Time: 4:10 p.m. ET
• Venue: PETCO Park -- San Diego, California
• Coverage: SDPA

Padres vs White Sox Odds & Moneyline

• All MLB odds, betting lines and prop bets are available on FanDuel Sportsbook.
• Moneyline: SD: (-290) | CHW: (+235)
• Spread: SD: -1.5 (-140) | CHW: +1.5 (+116)
• Total: 8 -- Over: (-118) | Under: (-104)

Padres vs White Sox Probable Starting Pitchers

Probable Pitchers: Yu Darvish (Padres) - 6-3, 3.21 ERA vs Sean Burke (White Sox) - 1-0, 2.25 ERA

This contest's pitching matchup is set, as the Padres will send Yu Darvish (6-3) to the mound, while Sean Burke (1-0) will answer the bell for the White Sox. Darvish and his team are 7-6-0 ATS this season when he starts. Darvish's team has been victorious in 71.4% of the games he's started as the moneyline favorite with a record of 5-2. Burke has started only one game with a set spread, which the White Sox covered. The White Sox were named the moneyline underdog for one Burke start this season -- they won.

Padres vs White Sox Moneyline

• The Padres vs White Sox moneyline has San Diego as a -290 favorite, while Chicago is a +235 underdog on the road.

Padres vs White Sox Spread

• The Padres are hosting the White Sox and are favored by 1.5 runs (-140 to cover) on the runline. Chicago is +116 to cover.

Padres vs White Sox Over/Under

• A total of 8 runs has been set for the Padres-White Sox game on Sept. 22, with the over available at -118 and the under at -104.

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Padres vs White Sox Betting Trends

• The Padres have been victorious in 56, or 57.7%, of the 97 contests they have been chosen as favorites in this season.
• This season San Diego has come away with a win two times in three chances when named as a favorite of at least -290 on the moneyline.
• Contests with the Padres have gone over the total set by oddsmakers in 80 of 153 chances this season.
• The Padres have an against the spread mark of 77-76-0 in 153 games with a line this season.
• The White Sox have won 29 of the 142 games they were the moneyline underdog this season (20.4%).
• When playing as a moneyline underdog with odds of +235 or longer, Chicago has a 3-14 record (winning only 17.6% of its games).
• In the 150 games bookmakers have set an over/under for the White Sox, they have combined with opponents to go over the total 66 times (66-78-6).
• The White Sox have put together a 60-90-0 record against the spread this season (covering 40% of the time).

Padres Player Leaders

• Jurickson Profar leads San Diego in OBP (.385) this season, fueled by 153 hits. He has a .283 batting average and a slugging percentage of .462.
• Among qualified hitters in the majors, he is 21st in batting average, sixth in on-base percentage, and 39th in slugging.
• Profar has recorded a base hit in two games in a row. During his last five outings he is batting .389 with two doubles, a home run, a walk and an RBI.
• Manny Machado is hitting .277 with 29 doubles, 29 home runs and 42 walks, while slugging .481 with an on-base percentage of .326.
• He is 28th in batting average, 63rd in on-base percentage and 23rd in slugging in the major leagues.
• Jackson Merrill leads San Diego in total hits (157) this season, and 59 of those have gone for extra bases.
• Merrill takes a three-game hitting streak into this game. During his last five outings he is batting .471 with two doubles, a home run, three walks and four RBI.
• Luis Arraez leads San Diego in slugging percentage (.388) thanks to 34 extra-base hits.

White Sox Player Leaders

• Andrew Vaughn has a team-high slugging percentage (.410) while pacing the White Sox in hits (133). He's batting .246 and with an on-base percentage of .299.
• Including all qualifying hitters in the big leagues, his batting average places him 85th, his on-base percentage is 112th, and he is 78th in slugging.
• Andrew Benintendi is hitting .226 with 19 doubles, 19 home runs and 41 walks. He's slugging .393 with an on-base percentage of .289.
• Including all qualified hitters, he is 119th in batting average, 122nd in on-base percentage and 98th in slugging percentage.
• Gavin Sheets has racked up an on-base percentage of .308, a team-best for the White Sox.
• Nicky Lopez is hitting .243 with 12 doubles, three triples, a home run and 37 walks.

Padres vs White Sox Head to Head

• 9/21/2024: 6-2 SD (Favorite: Padres, Spread: -1.5, Total: 8, Favorite Moneyline: -290, Underdog Moneyline: +235)
• 9/20/2024: 3-2 SD (Favorite: Padres, Spread: -1.5, Total: 7, Favorite Moneyline: -295, Underdog Moneyline: +240)
• 10/1/2023: 2-1 SD (Favorite: Padres, Spread: -1.5, Total: 9.5, Favorite Moneyline: -210, Underdog Moneyline: +176)
• 9/30/2023: 6-1 SD (Favorite: Padres, Spread: -1.5, Total: 8.5, Favorite Moneyline: -146, Underdog Moneyline: +124)
• 9/29/2023: 3-2 SD (Favorite: Padres, Spread: -1.5, Total: 8.5, Favorite Moneyline: -144, Underdog Moneyline: +122)
• 10/2/2022: 2-1 CHW (Favorite: Padres, Spread: -1.5, Total: 7, Favorite Moneyline: -162, Underdog Moneyline: +136)
• 10/1/2022: 5-2 SD (Favorite: Padres, Spread: -1.5, Total: 7, Favorite Moneyline: -110, Underdog Moneyline: -106)
• 9/30/2022: 3-1 CHW (Favorite: Padres, Spread: -1.5, Total: 7.5, Favorite Moneyline: -230, Underdog Moneyline: +190)

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