Padres vs Twins Prediction, Odds, Moneyline, Spread & Over/Under for Aug. 29

Odds updated as of 8:12 a.m.

The MLB's Friday schedule includes the San Diego Padres taking on the Minnesota Twins.

Before you do any MLB betting on this game at FanDuel Sportsbook, here's everything you need to know.

Padres vs Twins Game Info

• San Diego Padres (75-59) vs. Minnesota Twins (60-73)
• Date: Friday, August 29, 2025
• Time: 8:10 p.m. ET
• Venue: Target Field -- Minneapolis, Minnesota
• Coverage: MNNT and SDPA

Padres vs Twins Odds & Moneyline

• All MLB odds, betting lines and prop bets are available on FanDuel Sportsbook.
• Moneyline: SD: (-126) | MIN: (+108)
• Spread: SD: -1.5 (+134) | MIN: +1.5 (-162)
• Total: 8.5 -- Over: (-122) | Under: (-100)

Padres vs Twins Probable Starting Pitchers

Probable Pitchers: Nestor Cortes (Padres) - 2-2, 4.66 ERA vs Zebby Matthews (Twins) - 3-4, 5.30 ERA

The probable pitchers are Nestor Cortes (2-2) for the Padres and Zebby Matthews (3-4) for the Twins. Cortes' team is 3-3-0 against the spread in his starts this season. Cortes' team has a record of 2-1 this season when he starts and they are the favorite on the moneyline. The Twins have a 4-7-0 record against the spread in Matthews' starts. The Twins have been the moneyline underdog in four of Matthews' starts this season, and they went 2-2 in those games.

Padres vs Twins Prediction & Pick

All MLB win probability predictions and picks are according to numberFire.
Prediction: Twins win (54.2%)

Padres vs Twins Moneyline

• The moneyline numbers for Padres vs. Twins reveal San Diego as the favorite (-126) and Minnesota as the underdog (+108) despite being the home team.

Padres vs Twins Spread

• The Twins are at +1.5 on the runline against the Padres. The Twins are -162 to cover the spread, and the Padres are +134.

Padres vs Twins Over/Under

• The Padres-Twins game on Aug. 29 has been given an over/under of 8.5 runs. The over is set at -122 and the under at -100.

Bet on San Diego Padres vs. Minnesota Twins on FanDuel today!

Padres vs Twins Betting Trends

• The Padres have been chosen as favorites in 67 games this year and have walked away with the win 42 times (62.7%) in those games.
• This year San Diego has won 37 of 58 games when listed as at least -126 on the moneyline.
• The Padres' games have gone over the total in 57 of their 132 opportunities.
• The Padres are 74-58-0 against the spread in their 132 games that had a posted line this season.
• The Twins have won 36.7% of the games this season they were the moneyline underdog (18-31).
• When it has played as a moneyline underdog with odds of +108 or longer, Minnesota has gone 12-17 (41.4%).
• In the 128 games bookmakers have set an over/under for the Twins, they have combined with opponents to go over the total 58 times (58-63-7).
• The Twins have put together a 63-65-0 record against the spread this season.

Padres Player Leaders

• Fernando Tatis Jr. has 27 doubles, two triples, 18 home runs and 79 walks while hitting .264. He has an on-base percentage of .370 and a slugging percentage of .434.
• Among all qualifying hitters in baseball, his batting average ranks 63rd, his on-base percentage ranks 14th, and he is 77th in slugging.
• Tatis has hit safely in three straight games. In his last five games he is hitting .200 with two doubles, a home run, three walks and three RBIs.
• Manny Machado leads San Diego in slugging percentage (.471) and total hits (149) this season. He's batting .288 with an on-base percentage of .348.
• He is 17th in batting average, 43rd in on-base percentage and 44th in slugging in MLB.
• Luis Arraez has 147 hits this season and has a slash line of .283/.316/.388.
• Xander Bogaerts is batting .262 with a .330 OBP and 49 RBI for San Diego this season.
• Bogaerts has hit safely in three games in a row. During his last five outings he is hitting .235 with a double, a walk and three RBIs.

Twins Player Leaders

• Byron Buxton has accumulated a team-high slugging percentage (.539) and leads the Twins in hits (104). He's batting .269 and with an on-base percentage of .331.
• Including all the qualified players in the majors, he is 49th in batting average, 76th in on-base percentage and 10th in slugging percentage.
• Trevor Larnach is hitting .242 with 19 doubles, a triple, 16 home runs and 45 walks. He's slugging .405 with an on-base percentage of .318.
• He ranks 114th in batting average, 99th in on-base percentage and 104th in slugging percentage in MLB.
• Brooks Lee is batting .249 with 13 doubles, a triple, 14 home runs and 25 walks.
• Ryan Jeffers has a .347 OBP to lead his team.

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