Padres vs Marlins Prediction, Odds, Moneyline, Spread & Over/Under for May 27

Odds updated as of 9:12 p.m.

The San Diego Padres will face the Miami Marlins in MLB action on Tuesday.

We've got you covered, in terms of the vital information regarding this matchup before you take a look at the MLB odds and spreads on FanDuel Sportsbook.

Padres vs Marlins Game Info

• San Diego Padres (30-22) vs. Miami Marlins (21-31)
• Date: Tuesday, May 27, 2025
• Time: 9:40 p.m. ET
• Venue: PETCO Park -- San Diego, California
• Coverage: SDPA and FDSFL

Padres vs Marlins Odds & Moneyline

• All MLB odds, betting lines and prop bets are available on FanDuel Sportsbook.
• Moneyline: SD: (-162) | MIA: (+136)
• Spread: SD: -1.5 (+130) | MIA: +1.5 (-156)
• Total: 8 -- Over: (-104) | Under: (-118)

Padres vs Marlins Probable Starting Pitchers

Probable Pitchers: Stephen Kolek (Padres) - 2-1, 2.84 ERA vs Max Meyer (Marlins) - 3-4, 4.15 ERA

This contest's pitching matchup is set, as the Padres will send Stephen Kolek (2-1) to the mound, while Max Meyer (3-4) will get the nod for the Marlins. Kolek's team is 2-2-0 against the spread this season in his starts. Kolek's team is 1-2 this season when he starts and they are the moneyline favorite. The Marlins are 7-3-0 against the spread when Meyer starts. The Marlins are 3-4 in Meyer's seven starts this season that they were the underdog on the moneyline.

Padres vs Marlins Prediction & Pick

All MLB win probability predictions and picks are according to numberFire.
Prediction: Padres win (66.5%)

Padres vs Marlins Moneyline

• Looking at the moneyline for Marlins-Padres, Miami is the underdog at +136, and San Diego is -162 playing at home.

Padres vs Marlins Spread

• The Marlins are at the Padres, and are +1.5 on the runline. The Marlins are +130 to cover the spread, and the Padres are -156.

Padres vs Marlins Over/Under

• An over/under of 8 has been set for Padres-Marlins on May 27, with the over being -104 and the under -118.

Bet on San Diego Padres vs. Miami Marlins on FanDuel today!

Padres vs Marlins Betting Trends

• The Padres have come away with 17 wins in the 27 contests they have been listed as the favorites in this season.
• This season San Diego has been victorious 10 times in 14 chances when named as a favorite of at least -162 on the moneyline.
• The Padres and their opponents have hit the over in 21 of their 51 games with a total set by oddsmakers this season.
• The Padres are 27-24-0 against the spread in their 51 games that had a posted line this season.
• The Marlins have won 17 of the 46 games they were the underdog on the moneyline this season (37%).
• When it has played as a moneyline underdog with odds of +136 or longer, Miami has a record of 9-15 (37.5%).
• The Marlins have combined with opponents to hit the over on the total 30 times this season for a 30-22-0 record against the over/under.
• The Marlins have put together a 29-23-0 record ATS this season (covering 55.8% of the time).

Padres Player Leaders

• Manny Machado leads San Diego OPS (.888) this season. He has a .319 batting average, an on-base percentage of .391, and a slugging percentage of .497.
• He is eighth in batting average, 13th in on-base percentage, and 31st in slugging among qualifying hitters in baseball.
• Machado hopes to build on a four-game hitting streak in this matchup. During his last five outings he is hitting .368 with a double, three home runs, three walks and four RBIs.
• Fernando Tatis Jr. leads San Diego in total hits (55) this season while batting .275 with 20 extra-base hits. He's slugging .500 with an on-base percentage of .342.
• Among all qualified, he ranks 46th in batting average, 59th in on-base percentage and 27th in slugging percentage.
• Luis Arraez is batting .281 with a .405 slugging percentage and 16 RBI this year.
• Gavin Sheets leads San Diego with 45 hits, batting .274 this season with 17 extra-base hits.

Marlins Player Leaders

• Kyle Stowers has accumulated a team-high OBP (.369) and slugging percentage (.528), and paces the Marlins in hits (54, while batting .300).
• Including all qualified players in the big leagues, his batting average places him 14th, his on-base percentage ranks 32nd, and he is 19th in slugging.
• Eric Wagaman is hitting .246 with 10 doubles, a triple, four home runs and 13 walks. He's slugging .380 with an on-base percentage of .295.
• Including all qualified hitters, he ranks 96th in batting average, 128th in on-base percentage and 113th in slugging percentage.
• Otto Lopez is batting .222 with five doubles, three home runs and 14 walks.
• Agustin Ramirez is hitting .241 with 11 doubles, six home runs and 10 walks.

Padres vs Marlins Head to Head

• 5/26/2025: 4-3 SD (Favorite: Padres, Spread: -1.5, Total: 8, Favorite Moneyline: -152, Underdog Moneyline: +128)
• 8/11/2024: 7-6 MIA (Favorite: Padres, Spread: -1.5, Total: 7.5, Favorite Moneyline: -200, Underdog Moneyline: +168)
• 8/10/2024: 9-8 SD (Favorite: Padres, Spread: -1.5, Total: 8.5, Favorite Moneyline: -198, Underdog Moneyline: +166)
• 8/9/2024: 6-2 SD (Favorite: Padres, Spread: -1.5, Total: 8, Favorite Moneyline: -132, Underdog Moneyline: +112)
• 5/29/2024: 9-1 MIA (Favorite: Padres, Spread: -1.5, Total: 7, Favorite Moneyline: -184, Underdog Moneyline: +154)
• 5/28/2024: 4-0 SD (Favorite: Padres, Spread: -1.5, Total: 7, Favorite Moneyline: -136, Underdog Moneyline: +116)
• 5/27/2024: 2-1 SD (Favorite: Padres, Spread: -1.5, Total: 7.5, Favorite Moneyline: -196, Underdog Moneyline: +164)
• 8/23/2023: 4-0 SD (Favorite: Padres, Spread: -1.5, Total: 8, Favorite Moneyline: -126, Underdog Moneyline: +108)
• 8/22/2023: 3-0 MIA (Favorite: Padres, Spread: -1.5, Total: 7.5, Favorite Moneyline: -178, Underdog Moneyline: +150)
• 8/21/2023: 6-2 SD (Favorite: Padres, Spread: -1.5, Total: 8.5, Favorite Moneyline: -200, Underdog Moneyline: +168)

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