Padres vs Giants Prediction, Odds, Moneyline, Spread & Over/Under for March 30

Odds updated as of 9:12 p.m.

The MLB's Monday schedule includes the San Diego Padres facing the San Francisco Giants.

All the information you need to make smart bets on this game at FanDuel Sportsbook can be found below. Check out all of the latest MLB betting lines here.

Padres vs Giants Game Info

• San Diego Padres (1-2) vs. San Francisco Giants (0-3)
• Date: Monday, March 30, 2026
• Time: 9:40 p.m. ET
• Venue: Petco Park -- San Diego, California
• Coverage: Fox Sports 1, Padres.TV, and NBCS-BA

Padres vs Giants Odds & Moneyline

• All MLB odds, betting lines and prop bets are available on FanDuel Sportsbook.
• Moneyline: SD: (-118) | SF: (+100)
• Spread: SD: +1.5 (-205) | SF: -1.5 (+168)
• Total: 8.5 -- Over: (+102) | Under: (-124)

Padres vs Giants Probable Starting Pitchers

Probable Pitchers: Walker Buehler (Padres) - 0-0, 0.00 ERA vs Landen Roupp (Giants) - 0-0, 0.00 ERA

The Padres will give the nod to Walker Buehler against the Giants and Landen Roupp. In games Buehler pitched with a spread last season, his team was 12-12-0 ATS. Buehler and his team were 10-3 when he pitched and they were the moneyline favorite. Last season Roupp and his team were 11-11-0 against the spread in games he pitched. Roupp and his team went 7-7 in games he pitched when they were the moneyline underdog a season ago.

Padres vs Giants Prediction & Pick

All MLB win probability predictions and picks are according to numberFire.
Prediction: Padres win (50.7%)

Padres vs Giants Moneyline

• Looking at the moneyline for Padres-Giants, San Diego is the favorite at -118, and San Francisco is +100 playing on the road.

Padres vs Giants Spread

• The Giants are 1.5-run favorites against the spread for this matchup with the Padres. The Giants are +168 to cover, while the Padres are -205 to cover as a 1.5-run underdog on the runline.

Padres vs Giants Over/Under

• The over/under for the Padres versus Giants game on March 30 has been set at 8.5, with +102 odds on the over and -124 odds on the under.

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Padres vs Giants Betting Trends

• The Padres came away with 54 wins in the 89 contests they were listed as the favorites last season.
• Last season San Diego came away with a win 52 times in 85 chances when named as a favorite of at least -118 or shorter on the moneyline.
• The Padres and their opponents hit the over in 70 of their 163 games with a total last season.
• The Giants were the underdog on the moneyline 65 times last season. They went 29-36 in those games.
• San Francisco went 22-29 in games it played as a moneyline underdog with odds of +100 or longer (43.1%).
• The Giants played in 161 games with a set over/under last season, and combined with their opponents to go over the total 77 times (77-76-8).

Padres Player Leaders

• Fernando Tatis Jr. ended last season with an OBP of .368 while batting .268 with 89 walks and 111 runs scored.
• Manny Machado finished with 169 hits and a slugging percentage of .460.
• Last season, Ramon Laureano finished with 24 home runs, 76 RBI and a batting average of .281 last season.
• Xander Bogaerts slashed .263/.328/.391 and finished with an OPS of .720.

Giants Player Leaders

• Rafael Devers accumulated an on-base percentage of .372 and had 153 hits last season.
• Luis Arraez slugged .392 while batting .292.
• Willy Adames hit .225 with 22 doubles, two triples, 30 home runs and 80 walks a season ago.
• Jung Hoo Lee hit .266 with 31 doubles, 12 triples, eight home runs and 47 walks.

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