Padres vs Giants Prediction, Odds, Moneyline, Spread & Over/Under for March 30

Odds updated as of 6:14 a.m.

On Monday in MLB, the San Diego Padres are playing the San Francisco Giants.

Here's everything you need to know before checking out today's MLB odds and spreads on FanDuel Sportsbook.

Padres vs Giants Game Info

• San Diego Padres (1-2) vs. San Francisco Giants (0-3)
• Date: Monday, March 30, 2026
• Time: 9:40 p.m. ET
• Venue: Petco Park -- San Diego, California
• Coverage: Fox Sports 1, Padres.TV, and NBCS-BA

Padres vs Giants Odds & Moneyline

• All MLB odds, betting lines and prop bets are available on FanDuel Sportsbook.
• Moneyline: SD: (-118) | SF: (+100)
• Spread: SD: +1.5 (-205) | SF: -1.5 (+168)
• Total: 8.5 -- Over: (+102) | Under: (-124)

Padres vs Giants Probable Starting Pitchers

Probable Pitchers: Walker Buehler (Padres) - 0-0, 0.00 ERA vs Landen Roupp (Giants) - 0-0, 0.00 ERA

The Padres will give the nod to Walker Buehler against the Giants and Landen Roupp. In games Buehler pitched with a spread last season, his team was 12-12-0 ATS. Buehler and his team had a 10-3 record when he pitched as a favorite last season. Last season Roupp and his team went 11-11-0 against the spread when he pitched. Roupp and his team finished 7-7 in the 14 games he pitched when they were the underdog on the moneyline a season ago.

Padres vs Giants Prediction & Pick

All MLB win probability predictions and picks are according to numberFire.
Prediction: Padres win (51.1%)

Padres vs Giants Moneyline

• San Diego is the favorite, -118 on the moneyline, while San Francisco is a +100 underdog on the road.

Padres vs Giants Spread

• The Giants are 1.5-run favorites against the spread for this matchup with the Padres. The Giants are +168 to cover, while the Padres are -205 to cover as a 1.5-run underdog on the runline.

Padres vs Giants Over/Under

• A total of 8.5 runs has been set for the Padres-Giants game on March 30, with the over available at +102 and the under at -124.

Bet on San Diego Padres vs. San Francisco Giants on FanDuel today!

Padres vs Giants Betting Trends

• The Padres were chosen as favorites in 89 games last year and walked away with the win 54 times (60.7%) in those games.
• Last year, San Diego won 52 of 85 games when listed as at least -118 on the moneyline.
• The Padres and their opponents hit the over in 70 of their 163 games with a total last season.
• The Giants won 44.6% of the games last season they were the underdog on the moneyline (29-36).
• When playing as a moneyline underdog with odds of +100 or longer last year, San Francisco went 22-29 (43.1%).
• The Giants combined with their opponents to hit the over on the total 77 times last season for a 77-76-8 record against the over/under.

Padres Player Leaders

• Fernando Tatis Jr. ended last season with an OBP of .368 while batting .268 with 89 walks and 111 runs scored.
• Manny Machado had 169 hits to go with a slugging percentage of .460.
• Last season, Ramon Laureano finished with 24 home runs, 76 RBI and a batting average of .281 last season.
• Xander Bogaerts slashed .263/.328/.391 and finished with an OPS of .720.

Giants Player Leaders

• Rafael Devers racked up an OBP of .372 with 153 hits last season.
• Luis Arraez had a .392 slugging percentage while batting .292.
• Willy Adames hit .225 with 22 doubles, two triples, 30 home runs and 80 walks a season ago.
• Jung Hoo Lee hit .266 with 31 doubles, 12 triples, eight home runs and 47 walks.

Sign up for FanDuel Sportsbook and FanDuel Daily Fantasy today!