Padres vs Cubs Prediction, Odds, Moneyline, Spread & Over/Under for April 14

Odds updated as of 9:12 p.m.

The San Diego Padres versus the Chicago Cubs is on the MLB schedule for Monday.

We've got you covered, in terms of the most important information about this game before you take a look at the MLB odds and spreads on FanDuel Sportsbook.

Padres vs Cubs Game Info

• San Diego Padres (13-3) vs. Chicago Cubs (11-7)
• Date: Monday, April 14, 2025
• Time: 9:40 p.m. ET
• Venue: PETCO Park -- San Diego, California
• Coverage: SDPA and MARQ

Padres vs Cubs Odds & Moneyline

• All MLB odds, betting lines and prop bets are available on FanDuel Sportsbook.
• Moneyline: SD: (-148) | CHC: (+126)
• Spread: SD: -1.5 (+146) | CHC: +1.5 (-176)
• Total: 7.5 -- Over: (-100) | Under: (-122)

Padres vs Cubs Probable Starting Pitchers

Probable Pitchers: Dylan Cease (Padres) - 1-1, 7.98 ERA vs Jameson Taillon (Cubs) - 1-1, 6.06 ERA

The probable starters are Dylan Cease (1-1) for the Padres and Jameson Taillon (1-1) for the Cubs. Cease and his team are 1-2-0 ATS this season when he starts. Cease's team has a record of 2-1 this season when he starts and they are the favorite on the moneyline. The Cubs are 2-1-0 ATS in Taillon's three starts that had a set spread. The Cubs were the moneyline underdog for two Taillon starts this season -- they split the games.

Padres vs Cubs Prediction & Pick

All MLB win probability predictions and picks are according to numberFire.
Prediction: Padres win (61.4%)

Padres vs Cubs Moneyline

• Looking at the moneyline for Padres-Cubs, San Diego is the favorite at -148, and Chicago is +126 playing on the road.

Padres vs Cubs Spread

• The Cubs are at +1.5 on the runline against the Padres. The Cubs are -176 to cover the spread, and the Padres are +146.

Padres vs Cubs Over/Under

• Padres versus Cubs, on April 14, has an over/under of 7.5, with the over being -100 and the under -122.

Bet on San Diego Padres vs. Chicago Cubs on FanDuel today!

Padres vs Cubs Betting Trends

• The Padres have been favorites in 10 games this season and have come away with the win nine times (90%) in those contests.
• San Diego has been a -148 moneyline favorite on six occasions this season and won every time.
• The Padres and their opponents have gone over in seven of their 16 games with a total set by sportsbooks this season.
• The Padres are 11-5-0 against the spread in their 16 games that had a posted line this season.
• The Cubs have won 50% of the games this season they were the moneyline underdog (5-5).
• In games it has played as a moneyline underdog with odds of +126 or longer, Chicago has a record of 2-1 (66.7%).
• The Cubs have played in 18 games with a set over/under, and have combined with their opponents to go over the total 12 times (12-5-1).
• The Cubs are 11-7-0 ATS this season.

Padres Player Leaders

• Fernando Tatis Jr. leads San Diego with 20 hits and an OBP of .415, plus a team-best slugging percentage of .579. He's batting .351.
• Among all qualifying hitters in baseball, he ranks sixth in batting average, 12th in on-base percentage, and 17th in slugging.
• Tatis will look for his fourth straight game with a hit in this contest. During his last five outings he is batting .316 with three home runs, a walk and three RBI.
• Manny Machado has seven doubles, a home run and six walks. He's batting .317 and slugging .483 with an on-base percentage of .379.
• His batting average ranks 21st among qualified players, his on-base percentage 39th, and his slugging percentage 49th.
• Luis Arraez is batting .258 with a .333 slugging percentage and four RBI this year.
• Arraez has recorded at least one base hit in two straight games. During his last five outings he is batting .217 with .
• Xander Bogaerts is batting .304 with a .385 OBP and five RBI for San Diego this season.

Cubs Player Leaders

• Kyle Tucker has a team-best OBP (.442) and slugging percentage (.648), and paces the Cubs in hits (23, while batting .324).
• Including all the qualifying hitters in MLB, he is 15th in batting average, fifth in on-base percentage and eighth in slugging percentage.
• Tucker takes a three-game hitting streak into this game. During his last five outings he is hitting .316 with three doubles, three walks and two RBI.
• Carson Kelly is batting .417 with a double, a triple, four home runs and 11 walks. He's slugging 1.042 with an on-base percentage of .595.
• Seiya Suzuki has two doubles, a triple, four home runs and 11 walks while batting .292.
• Michael Busch is hitting .315 with four doubles, a triple, three home runs and four walks.

Padres vs Cubs Head to Head

• 4/6/2025: 8-7 SD (Favorite: Cubs, Spread: -1.5, Total: 7.5, Favorite Moneyline: -142, Underdog Moneyline: +120)
• 4/5/2025: 7-1 CHC (Favorite: Cubs, Spread: -1.5, Total: 6.5, Favorite Moneyline: -118, Underdog Moneyline: -100)
• 4/4/2025: 3-1 CHC (Favorite: Cubs, Spread: -1.5, Total: 7, Favorite Moneyline: -168, Underdog Moneyline: +142)
• 5/8/2024: 3-0 SD (Favorite: Padres, Spread: -1.5, Total: 7.5, Favorite Moneyline: -134, Underdog Moneyline: +114)
• 5/7/2024: 3-2 CHC (Favorite: Cubs, Spread: -1.5, Total: 9, Favorite Moneyline: -166, Underdog Moneyline: +140)
• 5/6/2024: 6-3 SD (Favorite: Cubs, Spread: -1.5, Total: 7.5, Favorite Moneyline: -116, Underdog Moneyline: -102)
• 4/10/2024: 10-2 SD (Favorite: Padres, Spread: -1.5, Total: 8, Favorite Moneyline: -152, Underdog Moneyline: +128)
• 4/9/2024: 5-1 CHC (Favorite: Padres, Spread: -1.5, Total: 8, Favorite Moneyline: -138, Underdog Moneyline: +118)
• 4/8/2024: 9-8 SD (Favorite: Padres, Spread: -1.5, Total: 7.5, Favorite Moneyline: -136, Underdog Moneyline: +116)
• 6/5/2023: 5-0 SD (Favorite: Padres, Spread: -1.5, Total: 8.5, Favorite Moneyline: -172, Underdog Moneyline: +144)

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