Padres vs Astros Prediction, Odds, Moneyline, Spread & Over/Under for Sept. 18

Odds updated as of 6:14 p.m.

MLB action on Wednesday includes the San Diego Padres taking on the Houston Astros.

Here's everything you need to know before checking out today's MLB odds and spreads on FanDuel Sportsbook.

Padres vs Astros Game Info

• San Diego Padres (86-66) vs. Houston Astros (82-69)
• Date: Wednesday, September 18, 2024
• Time: 6:40 p.m. ET
• Venue: PETCO Park -- San Diego, California
• Coverage: SCHN

Padres vs Astros Odds & Moneyline

• All MLB odds, betting lines and prop bets are available on FanDuel Sportsbook.
• Moneyline: SD: (-118) | HOU: (-100)
• Spread: SD: +1.5 (-205) | HOU: -1.5 (+168)
• Total: 7.5 -- Over: (-100) | Under: (-122)

Padres vs Astros Probable Starting Pitchers

Probable Pitchers: Dylan Cease (Padres) - 13-11, 3.58 ERA vs Framber Valdez (Astros) - 14-6, 2.91 ERA

The Padres will give the nod to Dylan Cease (13-11, 3.58 ERA), who is eyeing win No. 14 on the season, and the Astros will counter with Framber Valdez (14-6, 2.91 ERA). Cease's team is 17-14-0 against the spread in his starts this season. Cease's team is 17-11 this season when he starts and they are the moneyline favorite. The Astros are 16-10-0 against the spread when Valdez starts. The Astros are 2-2 in Valdez's four starts this season that they were the moneyline underdog.

Padres vs Astros Prediction & Pick

All MLB win probability predictions and picks are according to numberFire.
Prediction: Padres win (54.6%)

Padres vs Astros Moneyline

• The moneyline numbers for Padres vs. Astros reveal San Diego as the favorite (-118) and Houston as the underdog (-100) on the road.

Padres vs Astros Spread

• The Astros are 1.5-run favorites against the spread for this matchup with the Padres. The Astros are +168 to cover, while the Padres are -205 to cover as a 1.5-run underdog on the runline.

Padres vs Astros Over/Under

• Padres versus Astros, on Sept. 18, has an over/under of 7.5, with the over being -100 and the under -122.

Bet on San Diego Padres vs. Houston Astros on FanDuel today!

Padres vs Astros Betting Trends

• The Padres have been chosen as favorites in 94 games this year and have walked away with the win 53 times (56.4%) in those games.
• San Diego has a record of 45-36 in contests when bookmakers favor them by -118 or more on the moneyline.
• The Padres and their opponents have gone over in 80 of their 150 games with a total set by sportsbooks this season.
• The Padres are 75-75-0 against the spread in their 150 games that had a posted line this season.
• The Astros have been the moneyline underdog 39 total times this season. They've finished 19-20 in those games.
• When playing as a moneyline underdog with odds of -100 or longer, Houston has gone 10-11 (47.6%).
• The Astros have played in 151 games with a set over/under, and have combined with their opponents to go over the total 61 times (61-85-5).
• The Astros have put together a 75-76-0 record against the spread this season (covering 49.7% of the time).

Padres Player Leaders

• Jurickson Profar has 151 hits this season and a team-best OBP of .387. He has a .284 batting average and a slugging percentage of .465.
• Among all qualifying hitters in the majors, his batting average ranks 20th, his on-base percentage ranks fifth, and he is 37th in slugging.
• Profar hopes to build on a two-game hitting streak in this matchup. In his last five games he is batting .444 with a double, a home run, three walks and an RBI.
• Manny Machado is hitting .278 with 29 doubles, 27 home runs and 42 walks, while slugging .475 with an on-base percentage of .327.
• Among qualifying hitters, he is 27th in batting average, 64th in on-base percentage and 26th in slugging percentage.
• Machado takes a two-game streak with at least one hit into this matchup. During his last five outings he is hitting .364 with three doubles, a home run and eight RBI.
• Luis Arraez has hit four homers with a team-high .393 SLG this season.
• Jackson Merrill leads San Diego in total hits (151) this season while batting .288 with 57 extra-base hits.

Astros Player Leaders

• Yordan Alvarez has a team-high OBP (.392), while leading the Astros in hits (164). He's batting .307 and slugging.
• Including all the qualified hitters in the majors, he ranks fifth in batting average, fourth in on-base percentage and sixth in slugging percentage.
• Jose Altuve is slugging .445 to lead his team. He has a batting average of .301 with an on-base percentage of .356.
• Including all qualifying players, he ranks eighth in batting average, 22nd in on-base percentage and 53rd in slugging percentage.
• Alex Bregman is batting .256 with 28 doubles, two triples, 23 home runs and 42 walks.
• Yainer Diaz is batting .297 with 26 doubles, three triples, 16 home runs and 23 walks.

Padres vs Astros Head to Head

• 9/17/2024: 4-3 HOU (Favorite: Padres, Spread: -1.5, Total: 7.5, Favorite Moneyline: -118, Underdog Moneyline: -100)
• 9/16/2024: 3-1 SD (Favorite: Padres, Spread: -1.5, Total: 7.5, Favorite Moneyline: -118, Underdog Moneyline: -100)
• 9/10/2023: 12-2 HOU (Favorite: Astros, Spread: -1.5, Total: 10, Favorite Moneyline: -188, Underdog Moneyline: +158)
• 9/9/2023: 7-5 HOU (Favorite: Astros, Spread: -1.5, Total: 9, Favorite Moneyline: -120, Underdog Moneyline: +102)
• 9/8/2023: 11-2 SD (Favorite: Astros, Spread: -1.5, Total: 8.5, Favorite Moneyline: -142, Underdog Moneyline: +120)

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