Padres vs Astros Prediction, Odds, Moneyline, Spread & Over/Under for Sept. 16

Odds updated as of 9:11 p.m.

The San Diego Padres will take on the Houston Astros in MLB action on Monday.

Before you do any MLB betting on this game at FanDuel Sportsbook, here's everything you need to know.

Padres vs Astros Game Info

• San Diego Padres (85-65) vs. Houston Astros (81-68)
• Date: Monday, September 16, 2024
• Time: 9:40 p.m. ET
• Venue: PETCO Park -- San Diego, California
• Coverage: SDPA

Padres vs Astros Odds & Moneyline

• All MLB odds, betting lines and prop bets are available on FanDuel Sportsbook.
• Moneyline: SD: (-118) | HOU: (-100)
• Spread: SD: +1.5 (-210) | HOU: -1.5 (+172)
• Total: 7.5 -- Over: (-120) | Under: (-102)

Padres vs Astros Probable Starting Pitchers

Probable Pitchers: Yu Darvish (Padres) - 5-3, 3.52 ERA vs Spencer Arrighetti (Astros) - 7-12, 4.72 ERA

The Padres will give the ball to Yu Darvish (5-3, 3.52 ERA), who is eyeing win No. 6 on the season, and the Astros will counter with Spencer Arrighetti (7-12, 4.72 ERA). Darvish and his team are 6-6-0 ATS this season when he starts. When Darvish starts a game and his team is the favorite on the moneyline, they have a record of 4-2. When Arrighetti starts, the Astros are 11-15-0 against the spread. The Astros have been the underdog on the moneyline in eight of Arrighetti's starts this season, and they went 3-5 in those games.

Padres vs Astros Prediction & Pick

All MLB win probability predictions and picks are according to numberFire.
Prediction: Padres win (52.9%)

Padres vs Astros Moneyline

• San Diego is a -118 favorite on the moneyline, while Houston is a -100 underdog on the road.

Padres vs Astros Spread

• The Astros are 1.5-run favorites against the spread for this matchup with the Padres. The Astros are +172 to cover, while the Padres are -210 to cover as a 1.5-run underdog on the runline.

Padres vs Astros Over/Under

• Padres versus Astros on Sept. 16 has an over/under of 7.5 runs, with the odds on the over -120 and the under set at -102.

Bet on San Diego Padres vs. Houston Astros on FanDuel today!

Padres vs Astros Betting Trends

• The Padres have been favorites in 92 games this season and have come away with the win 52 times (56.5%) in those contests.
• San Diego has a record of 44-35 in contests when sportsbooks favor them by -118 or more on the moneyline.
• The Padres' games have gone over the total in 80 of their 148 opportunities.
• In 148 games with a line this season, the Padres have a mark of 73-75-0 against the spread.
• The Astros have won 48.6% of the games this season they were the underdog on the moneyline (18-19).
• In games it has played as a moneyline underdog with odds of -100 or longer, Houston has gone 10-11 (47.6%).
• The Astros have had an over/under set by bookmakers 149 times, and have combined with opponents to go over the total in 61 of those games (61-83-5).
• The Astros have a 75-74-0 record ATS this season.

Padres Player Leaders

• Jurickson Profar leads San Diego in OBP (.382) this season, fueled by 146 hits. He has a .279 batting average and a slugging percentage of .455.
• Among the qualified hitters in MLB, his batting average ranks 26th, his on-base percentage ranks seventh, and he is 43rd in slugging.
• Luis Arraez has an OPS of .749, fueled by an OBP of .356 and a team-best slugging percentage of .394 this season. He's batting .322.
• Among qualifying batters, he is second in batting average, 21st in on-base percentage and 100th in slugging percentage.
• Arraez brings a 13-game streak with at least one hit into this one. In his last 10 games he is batting .457 with two doubles, three walks and two RBI.
• Manny Machado has 151 hits this season and has a slash line of .275/.326/.468.
• Jackson Merrill leads San Diego with 149 hits, batting .288 this season with 56 extra-base hits.

Astros Player Leaders

• Yordan Alvarez has racked up 162 hits with a .393 on-base percentage, leading the Astros in both categories. He's batting .308 and slugging .568.
• Including all qualified players, he ranks fifth in batting average, while his on-base percentage is fourth and he is fifth in slugging.
• Jose Altuve's .445 slugging percentage leads his team. He has a batting average of .301 with an on-base percentage of .356.
• Including all qualified hitters, his batting average puts him seventh, his on-base percentage is 21st, and he is 51st in slugging.
• Alex Bregman is hitting .256 with 28 doubles, two triples, 23 home runs and 41 walks.
• Yainer Diaz has 26 doubles, three triples, 16 home runs and 23 walks while batting .301.

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