Orioles vs Nationals Prediction, Odds, Moneyline, Spread & Over/Under for April 23

Odds updated as of 6:12 p.m.

Wednesday's slate in the MLB includes a matchup between the Baltimore Orioles and the Washington Nationals.

Before you do any MLB betting on this matchup at FanDuel Sportsbook, here's what you need to know.

Orioles vs Nationals Game Info

• Baltimore Orioles (9-13) vs. Washington Nationals (10-13)
• Date: Wednesday, April 23, 2025
• Time: 6:45 p.m. ET
• Venue: Nationals Park -- Washington, District of Columbia
• Coverage: MASN and MASN2

Orioles vs Nationals Odds & Moneyline

• All MLB odds, betting lines and prop bets are available on FanDuel Sportsbook.
• Moneyline: BAL: (-142) | WSH: (+120)
• Spread: BAL: -1.5 (+110) | WSH: +1.5 (-132)
• Total: 9.5 -- Over: (-104) | Under: (-118)

Orioles vs Nationals Probable Starting Pitchers

Probable Pitchers: Tomoyuki Sugano (Orioles) - 2-1, 3.43 ERA vs Trevor Williams (Nationals) - 1-2, 5.95 ERA

The Orioles will give the nod to Tomoyuki Sugano (2-1, 3.43 ERA), who is eyeing win No. 3 on the season, and the Nationals will turn to Trevor Williams (1-2, 5.95 ERA). Sugano's team is 2-2-0 against the spread this season in his starts. Sugano's team is 2-0 this season when he starts and they're favored on the moneyline. When Williams starts, the Nationals have gone 3-1-0 against the spread. The Nationals have been the underdog on the moneyline in four of Williams' starts this season, and they went 1-3 in those matchups.

Orioles vs Nationals Prediction & Pick

All MLB win probability predictions and picks are according to numberFire.
Prediction: Nationals win (52.4%)

Orioles vs Nationals Moneyline

• Looking at the moneyline for Nationals-Orioles, Washington is the underdog at +120, and Baltimore is -142 playing on the road.

Orioles vs Nationals Spread

• The Orioles are at the Nationals and are favored by 1.5 runs on the spread. The Orioles are +110 to cover the runline, with the Nationals being -132.

Orioles vs Nationals Over/Under

• The over/under for the Orioles versus Nationals contest on April 23 has been set at 9.5, with -104 odds on the over and -118 odds on the under.

Bet on Baltimore Orioles vs. Washington Nationals on FanDuel today!

Orioles vs Nationals Betting Trends

• The Orioles have come away with five wins in the 13 contests they have been listed as the favorites in this season.
• Baltimore has a record of 1-3 in contests when sportsbooks favor them by -142 or more on the moneyline.
• The Orioles and their opponents have gone over the total this season in 14 of their 22 opportunities.
• The Orioles have posted a record of 8-14-0 against the spread this season.
• The Nationals have won eight of the 18 games they were the moneyline underdog this season (44.4%).
• Washington has a 3-8 record (winning just 27.3% of its games) when it has played as a moneyline underdog of +120 or longer.
• In the 23 games oddsmakers have set an over/under for the Nationals, they have combined with opponents to go over the total 12 times (12-11-0).
• The Nationals have an 11-12-0 record ATS this season (covering 47.8% of the time).

Orioles Player Leaders

• Cedric Mullins leads Baltimore with 20 hits and an OBP of .443, plus a team-best slugging percentage of .623. He's batting .290.
• Among qualifying hitters in MLB, his batting average ranks 41st, his on-base percentage ranks fourth, and he is seventh in slugging.
• Mullins has picked up at least one hit in four games in a row. In his last five games he is hitting .235 with two home runs, five walks and two RBI.
• Adley Rutschman has two doubles, four home runs and 11 walks. He's batting .200 and slugging .375 with an on-base percentage of .297.
• He is 130th in batting average, 113th in on-base percentage and 102nd in slugging among qualified batters.
• Ryan O'Hearn has 16 hits this season and has a slash line of .296/.377/.519.
• Jordan Westburg is batting .187 with a .247 OBP and five RBI for Baltimore this season.

Nationals Player Leaders

• James Wood is leading the Nationals with 22 hits. He's batting .253 and slugging .552 with an on-base percentage of .350.
• Including all the qualifying players in the majors, he ranks 78th in batting average, 59th in on-base percentage and 17th in slugging percentage.
• Keibert Ruiz's .378 OBP and .461 slugging percentage both lead his team. He has a batting average of .329.
• His batting average ranks 14th among all qualified players, his on-base percentage is 30th, and he is 53rd in slugging.
• Nate Lowe is hitting .293 with five doubles, four home runs and 10 walks.
• Luis Garcia is hitting .225 with three doubles, a home run and six walks.

Orioles vs Nationals Head to Head

• 4/22/2025: 7-0 WSH (Favorite: Orioles, Spread: -1.5, Total: 9, Favorite Moneyline: -136, Underdog Moneyline: +116)
• 8/14/2024: 4-1 BAL (Favorite: Orioles, Spread: -1.5, Total: 8.5, Favorite Moneyline: -172, Underdog Moneyline: +144)
• 8/13/2024: 9-3 WSH (Favorite: Orioles, Spread: -1.5, Total: 9, Favorite Moneyline: -184, Underdog Moneyline: +154)
• 5/8/2024: 7-6 BAL (Favorite: Orioles, Spread: -1.5, Total: 8.5, Favorite Moneyline: -174, Underdog Moneyline: +146)
• 5/7/2024: 3-0 WSH (Favorite: Orioles, Spread: -1.5, Total: 8.5, Favorite Moneyline: -215, Underdog Moneyline: +180)
• 9/27/2023: 5-1 BAL (Favorite: Orioles, Spread: -1.5, Total: 7.5, Favorite Moneyline: -255, Underdog Moneyline: +210)
• 9/26/2023: 1-0 BAL (Favorite: Orioles, Spread: -1.5, Total: 7.5, Favorite Moneyline: -250, Underdog Moneyline: +205)
• 4/19/2023: 4-0 BAL (Favorite: Orioles, Spread: -1.5, Total: 8.5, Favorite Moneyline: -142, Underdog Moneyline: +120)
• 4/18/2023: 1-0 BAL (Favorite: Orioles, Spread: -1.5, Total: 8.5, Favorite Moneyline: -148, Underdog Moneyline: +126)
• 9/14/2022: 6-2 BAL (Favorite: Orioles, Spread: -1.5, Total: 8.5, Favorite Moneyline: -154, Underdog Moneyline: +130)

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