Orioles vs Diamondbacks Prediction, Odds, Moneyline, Spread & Over/Under for April 15

Odds updated as of 9:11 p.m.

The Baltimore Orioles versus the Arizona Diamondbacks is on the MLB schedule for Wednesday.

All the information you need to make smart wagers on this game at FanDuel Sportsbook can be found below. Check out all of the latest MLB betting lines here.

Orioles vs Diamondbacks Game Info

• Baltimore Orioles (9-7) vs. Arizona Diamondbacks (9-8)
• Date: Wednesday, April 15, 2026
• Time: 12:35 p.m. ET
• Venue: Oriole Park at Camden Yards -- Baltimore, Maryland
• Coverage: MASN and Dbacks.TV

Orioles vs Diamondbacks Odds & Moneyline

• All MLB odds, betting lines and prop bets are available on FanDuel Sportsbook.
• Moneyline: BAL: (-156) | ARI: (+132)
• Spread: BAL: -1.5 (+128) | ARI: +1.5 (-154)
• Total: 9 -- Over: (-105) | Under: (-115)

Orioles vs Diamondbacks Probable Starting Pitchers

Probable Pitchers: Kyle Bradish (Orioles) - 1-2, 5.27 ERA vs Eduardo Rodríguez (Diamondbacks) - 1-0, 0.50 ERA

The Orioles will give the ball to Kyle Bradish (1-2, 5.27 ERA), who is eyeing win No. 2 on the season, and the Diamondbacks will turn to Eduardo Rodriguez (1-0, 0.50 ERA). Bradish's team is 1-2-0 against the spread in his starts this season. Bradish's team has won 33.3% of his starts when they are favored on the moneyline (1-2). The Diamondbacks have gone 2-1-0 ATS in Rodríguez's three starts with a set spread. The Diamondbacks are 1-2 in Rodríguez's three starts this season that they were the underdog on the moneyline.

Orioles vs Diamondbacks Prediction & Pick

All MLB win probability predictions and picks are according to numberFire.
Prediction: Diamondbacks win (51.2%)

Orioles vs Diamondbacks Moneyline

• Arizona is the underdog, +132 on the moneyline, while Baltimore is a -156 favorite at home.

Orioles vs Diamondbacks Spread

• The Diamondbacks are +1.5 on the run line against the Orioles. The Diamondbacks are -154 to cover, and the Orioles are +128.

Orioles vs Diamondbacks Over/Under

• The over/under for the Orioles versus Diamondbacks game on April 15 has been set at 9, with -105 odds on the over and -115 odds on the under.

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Orioles vs Diamondbacks Betting Trends

• The Orioles have been chosen as favorites in 12 games this year and have walked away with the win eight times (66.7%) in those games.
• Baltimore has played as a favorite of -156 or more just one time this year and came away with a loss in that game.
• The Orioles and their opponents have gone over in nine of their 16 games with a total set by sportsbooks this season.
• The Orioles are 7-9-0 against the spread in their 16 games with a line set by sportsbooks this season.
• The Diamondbacks have won 38.5% of the games this season they were the moneyline underdog (5-8).
• When playing as a moneyline underdog with odds of +132 or longer, Arizona has a 2-3 record (winning 40% of its games).
• The Diamondbacks have played in 17 games with a set over/under, and have combined with opponents to go over the total 10 times (10-6-1).
• The Diamondbacks have put together a 13-4-0 record against the spread this season (covering 76.5% of the time).

Orioles Player Leaders

• Gunnar Henderson has 16 hits, which ranks first among Baltimore hitters this season, while batting .239 with 10 extra-base hits. He has an on-base percentage of .329 and a slugging percentage of .582.
• Among qualifying hitters in MLB, his batting average ranks 95th, his on-base percentage ranks 91st, and he is 16th in slugging.
• Henderson hopes to build on a seven-game hitting streak in this matchup. In his last 10 games he is hitting .286 with two doubles, a triple, five home runs, six walks and nine RBIs.
• Taylor Ward has a slash line of .333/.427/.492 this season and a team-best OPS of .919.
• Among qualified batters, he is 11th in batting average, 15th in on-base percentage and 44th in slugging percentage.
• Pete Alonso is batting .213 with a .377 slugging percentage and seven RBI this year.
• Alonso has picked up a hit in two games in a row. During his last five outings he is hitting .278 with three doubles, a home run, four walks and four RBIs.
• Jeremiah Jackson has three home runs, 11 RBI and a batting average of .318 this season.
• Jackson enters this game on a four-game hitting streak. In his last five games he is batting .400 with a double, three home runs and seven RBIs.

Diamondbacks Player Leaders

• Corbin Carroll has accumulated a team-high OBP (.403) and slugging percentage (.623), while leading the Diamondbacks in hits (17, while batting .321).
• He is 15th in batting average, 21st in on-base percentage and eighth in slugging percentage among all qualifying hitters in MLB.
• Ketel Marte is hitting .212 with two doubles, four home runs and six walks. He's slugging .424 with an on-base percentage of .278.
• His batting average is 128th among all qualified players, his on-base percentage ranks 148th, and he is 72nd in slugging.
• Geraldo Perdomo has two doubles, a home run and 11 walks while batting .148.
• Ildemaro Vargas is batting .405 with four doubles, a triple, a home run and two walks.

Orioles vs Diamondbacks Head to Head

• 4/13/2026: 9-7 BAL (Favorite: Orioles, Spread: -1.5, Total: 9, Favorite Moneyline: -130, Underdog Moneyline: +110)
• 4/9/2025: 9-0 ARI (Favorite: Diamondbacks, Spread: -1.5, Total: 9, Favorite Moneyline: -118, Underdog Moneyline: -100)
• 4/8/2025: 4-3 ARI (Favorite: Orioles, Spread: -1.5, Total: 9.5, Favorite Moneyline: -112, Underdog Moneyline: -104)
• 4/7/2025: 5-1 BAL (Favorite: Diamondbacks, Spread: -1.5, Total: 8.5, Favorite Moneyline: -124, Underdog Moneyline: +106)
• 5/12/2024: 9-2 ARI (Favorite: Orioles, Spread: -1.5, Total: 7.5, Favorite Moneyline: -130, Underdog Moneyline: +110)
• 5/11/2024: 5-4 BAL (Favorite: Orioles, Spread: -1.5, Total: 8.5, Favorite Moneyline: -152, Underdog Moneyline: +128)
• 5/10/2024: 4-2 BAL (Favorite: Orioles, Spread: -1.5, Total: 7.5, Favorite Moneyline: -132, Underdog Moneyline: +112)
• 9/3/2023: 8-5 BAL (Favorite: Diamondbacks, Spread: -1.5, Total: 8.5, Favorite Moneyline: -142, Underdog Moneyline: +120)
• 9/2/2023: 7-3 BAL (Favorite: Orioles, Spread: -1.5, Total: 9, Favorite Moneyline: -132, Underdog Moneyline: +112)
• 9/1/2023: 4-2 ARI (Favorite: Orioles, Spread: -1.5, Total: 9.5, Favorite Moneyline: -116, Underdog Moneyline: -102)

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