Ole Miss vs Vanderbilt Prediction, College Football Picks, Odds and Best Bets Today

Ole Miss vs Vanderbilt Prediction in Summary

• Ole Miss -9.5
• Ole Miss Moneyline
• Over 54.5
• Prediction: Ole Miss wins comfortably in a high-scoring game

Ole Miss travels to Vanderbilt Saturday, and the market sees a real gap between the two sides — a -350 road favorite laying 9.5 points, with a total near 55 signaling that both offenses are expected to find the end zone with regularity. The site's own popular parlay leans on both Deuce Alexander and Trinidad Chambliss finding the end zone.

All college football odds come from FanDuel Sportsbook's college football betting odds and may change after this article is published.

Ole Miss vs Vanderbilt Odds & Best Bets

Ole Miss at Vanderbilt (Sat, 3:30 p.m. ET)

Ole Miss -9.5 (-112)

Ole Miss's own total yardage line (428.5) sits well above Vanderbilt's (358.5), a clear sign the market expects a real edge on both sides of the ball on the road.

Ole Miss Moneyline (-350)

Trinidad Chambliss is half of the site's own popular parlay this week, a real sign the market gives Ole Miss a genuine edge even on the road against an SEC opponent.

Over 54.5 (-114)

One of the higher totals of the entire college football slate this week, a real sign the market expects both offenses to find the end zone with real regularity.

Ole Miss vs Vanderbilt Prediction

Ole Miss's real advantage on paper — both in moneyline price and projected yardage — points to a comfortable road win. With the total sitting near 55, expect Vanderbilt's offense to stay involved even in a loss rather than get completely shut out. Look for Ole Miss to cover behind a balanced offensive attack while the total pushes well past the number.