Northwestern vs Iowa Prediction, Odds, Picks, Best Bets for Week 10 2026

In college football action on Saturday, the Iowa Hawkeyes take on the Northwestern Wildcats.

Before you make your wager on FanDuel Sportsbook, we've got you covered with all the latest NCAA football betting insights.

Iowa vs Northwestern Odds & Spread

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• All college football odds, betting lines and prop bets are available on FanDuel Sportsbook.
• Moneyline: Iowa: (-132) | Northwestern: (+110)
• Spread: Iowa: -2.5 (-112) | Northwestern: +2.5 (-108)
• Total: 43.5 -- Over: (-108) | Under: (-112)

Iowa vs Northwestern Betting Trends

• Iowa is 5-3-0 against the spread this year.
• As 2.5-point favorites or more, Iowa is 3-2 against the spread.
• Two of Iowa's eight games have gone over the point total.
• Northwestern's record against the spread in 2026 is 5-3-0.
• As a 2.5-point underdog or more, Northwestern has two wins ATS (2-1).
• Northwestern has played eight games this season, and five of them have gone over the total.

Iowa vs Northwestern Prediction & Pick

All college football win probability predictions and picks are according to numberFire.
Prediction: Wildcats win (52.1%)

Iowa vs Northwestern Point Spread

Iowa is favored by 2.5 points over Northwestern. Iowa is -112 to cover the spread, with Northwestern being -108.

Iowa vs Northwestern Over/Under

The over/under for Iowa-Northwestern on Nov. 7 is 43.5. The over is -108, and the under is -112.

Iowa vs Northwestern Moneyline

Northwestern is a +110 underdog on the moneyline, while Iowa is a -132 favorite.

Iowa vs. Northwestern Points Insights

Iowa vs. Northwestern Game Info

• Game day: Saturday, November 7, 2026
• Game time: 7:30 p.m. ET
• TV channel: FOX
• Location: Evanston, Illinois
• Stadium: Ryan Field

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Check out even more in-depth Iowa vs. Northwestern analysis on FanDuel Research.