NFL Week 4 Schedule: Odds for Every Game

NFL Week 4 Schedule Highlights

• Patriots at Bills
• Jaguars at Bengals
• Rams at Eagles
• Broncos at 49ers

Week 3 of the 2026 NFL season is nearly in the books, which means it's time to turn our attention to Week 5.

The fourth week of the season features another 16-game slate, beginning on Thursday night and concluding with a Monday night matchup between the Falcons and Saints.

Here's the complete NFL Week 4 schedule, including the betting odds, date and kickoff time for every game.

All NFL odds via FanDuel Sportsbook, and they may change after this article is published.

Week 4 NFL Odds and Schedule

Thursday, October 1

Pittsburgh Steelers at Cleveland Browns

Sunday, October 4

Indianapolis Colts vs. Washington Commanders

Arizona Cardinals at New York Giants

New England Patriots at Buffalo Bills

New York Jets at Chicago Bears

Dallas Cowboys at Houston Texans

Los Angeles Rams at Philadelphia Eagles

Green Bay Packers at Tampa Bay Buccaneers

Tennessee Titans at Baltimore Ravens

Jacksonville Jaguars at Cincinnati Bengals

Miami Dolphins at Minnesota Vikings

Kansas City Chiefs at Las Vegas Raiders

Los Angeles Chargers at Seattle Seahawks

Denver Broncos at San Francisco 49ers

Detroit Lions at Carolina Panthers

Monday, October 5

Atlanta Falcons at New Orleans Saints

NFL Betting FAQ

What is the point spread in NFL betting?

The sportsbook assigns a favorite (indicated by a minus sign, like -6.5) and an underdog (indicated by a plus sign, like +6.5). If you bet the favorite, in this example, they need to win by more than 6.5 points for your bet to win. If you bet the underdog, they need to either win outright or lose by fewer than 6.5 points. The half-point eliminates the possibility of a push (tie).

What does moneyline betting mean in the NFL?

A moneyline bet is a straight-up wager on which team wins the game — no spread involved. Favorites carry a negative number (e.g., -180), meaning you'd need to wager $180 to win $100. Underdogs carry a positive number (e.g., +155), meaning a $100 bet would return $155 in profit. Moneylines allow you to back a team without having to worry about margin of victory.

What is the over/under (total) in NFL betting?

The over/under — also called the total — is a bet on the combined score of both teams. FanDuel Sportsbook sets a number (for example, 47.5 points), and you wager on whether the final total will add up to more than 47.5 points or fewer than 47.5 points. It doesn't matter which team wins; all that counts is how many points are scored in regulation and overtime combined.

What are NFL player props?

Player props are individual performance bets focused on a specific player's stats rather than the game outcome. You can bet on a player to go over or under. Common NFL props include passing yards, rushing yards, receiving yards, touchdowns, receptions, and completions. FanDuel Sportsbook offers a wide variety of player props for every game, often including alternate lines at adjusted odds.

What is a same-game parlay (SGP)?

A same-game parlay lets you bundle multiple bets from the same NFL game — such as a team to cover the spread, a quarterback to throw for over 275 yards, and a wide receiver to score a touchdown — all into one ticket. Because the outcomes are correlated, the odds are adjusted accordingly. FanDuel Sportsbook offers same-game parlays for every game on the slate.

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Which NFL bets stand out to you? Check out FanDuel Sportsbook's latest NFL odds to see the full menu of options.

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The above author is a FanDuel employee and is not eligible to compete in public daily fantasy contests or place sports betting wagers on FanDuel. The advice provided by the author does not necessarily represent the views of FanDuel. Taking the author's advice will not guarantee a successful outcome. You should use your own judgment when participating in daily fantasy contests or placing sports wagers.