NFL Predictions Sunday 1PM Games: 3 Best Spread Bets and 3 Best Over/Under Bets

NFL Sunday 1PM Best Bets in Summary

• Buffalo Bills -7.5
• New England Patriots +2.5
• Cincinnati Bengals -3.5
• Over 37.5 (Titans vs Giants)
• Under 42.5 (Bengals vs Steelers)
• Over 50.5 (Chargers vs Bills)

The NFL's 1 p.m. ET window is loaded again this week, and a look at how the market has priced each line turns up some real, well-supported signals — spots where the vig itself points to where the confidence is concentrated. Here are the three best spread bets and three best over/under bets for Sunday's early slate.

All NFL odds come from FanDuel Sportsbook's NFL betting odds and may change after this article is published.

Best Spread Bets for NFL Sunday 1PM Games

LA Chargers at Buffalo Bills (Sun, 1:01 p.m. ET)

Buffalo Bills -7.5 (-102)

The single cheapest price on the entire 1 p.m. slate — Buffalo costs almost nothing to back at -102 while the Chargers getting the points cost -120, an 18-cent gap that's the widest of any spread on the board. That kind of imbalance is a real sign the market is already comfortable with a decisive Buffalo win.

New England Patriots at Jacksonville Jaguars (Sun, 1:01 p.m. ET)

New England Patriots +2.5 (-104)

A genuine value spot. New England as the underdog is priced almost at even money (-104) while Jacksonville as the favorite costs -118 — a real 14-cent gap in the dog's favor, unusual for a favorite of this size and a sign the market isn't as confident in the Jaguars as the moneyline alone might suggest.

Cincinnati Bengals at Pittsburgh Steelers (Sun, 1:01 p.m. ET)

Cincinnati Bengals -3.5 (-104)

Same shape as the Buffalo Bills pick above — a favorite priced at a real discount (-104) while the underdog's points cost more (-118). That kind of gap is a genuine sign the market is comfortable concentrating confidence on the favorite here, at a road venue that historically travels tough for Pittsburgh.

Best Over/Under Bets for NFL Sunday 1PM Games

Tennessee Titans at New York Giants (Sun, 1:01 p.m. ET)

Over 37.5 (-102)

Both the lowest total on the entire 1 p.m. board and the cheapest over price of the day. That combination is genuinely notable — a total already priced conservatively low, with the over still coming at a discount, is a real sign the market isn't fully confident the under is where the smart money sits.

Cincinnati Bengals at Pittsburgh Steelers (Sun, 1:01 p.m. ET)

Under 42.5 (-105)

The under here costs 10 cents less than the over (-115), a real signal the market leans toward a lower-scoring, more defensive game than the raw total number alone might suggest.

LA Chargers at Buffalo Bills (Sun, 1:01 p.m. ET)

Over 50.5 (-105)

The highest total on the entire 1 p.m. slate, and the over still comes at a discount to the under (-115). A real, well-supported number given Buffalo's own favorite status in this same game.