NFL Odds Week 10: Schedule, Betting Odds for Every Game

NFL Week 10 Schedule Highlights

• Detroit Lions vs. New England Patriots
• Minnesota Vikings at Green Bay Packers
• San Francisco 49ers at Dallas Cowboys
• Pittsburgh Steelers at Cincinnati Bengals

We’re already at Week 10 of the 2026 NFL season, and this week features our next to last international game of the campaign along with some crucial division matchups.

Below is the complete NFL Week 10 schedule with betting odds, date and kickoff time for every game.

All NFL odds via FanDuel Sportsbook, and they may change after this article is published.

NFL Odds and Schedule for This Week (Week 10)

Thursday, November 12

Washington Commanders vs. New York Giants

Sunday, November 15

New England Patriots vs. Detroit Lions

Kansas City Chiefs vs. Atlanta Falcons

Buffalo Bills vs. New York Jets

Miami Dolphins vs. Indianapolis Colts

Minnesota Vikings vs. Green Bay Packers

Carolina Panthers vs. New Orleans Saints

Jacksonville Jaguars vs. Tennessee Titans

Houston Texans vs. Cleveland Browns

Seattle Seahawks vs. Las Vegas Raiders

Los Angeles Rams vs. Arizona Cardinals

San Francisco 49ers vs. Dallas Cowboys

Pittsburgh Steelers vs. Cincinnati Bengals

Monday, November 16

Los Angeles Chargers vs. Baltimore Ravens

What is the point spread in NFL betting?

The sportsbook assigns a favorite (indicated by a minus sign, like -6.5) and an underdog (indicated by a plus sign, like +6.5). If you bet the favorite, in this example, they need to win by more than 6.5 points for your bet to win. If you bet the underdog, they need to either win outright or lose by fewer than 6.5 points. The half-point eliminates the possibility of a push (tie).

What does moneyline betting mean in the NFL?

A moneyline bet is a straight-up wager on which team wins the game — no spread involved. Favorites carry a negative number (e.g., -180), meaning you'd need to wager $180 to win $100. Underdogs carry a positive number (e.g., +155), meaning a $100 bet would return $155 in profit. Moneylines allow you to back a team without having to worry about margin of victory.

What is the over/under (total) in NFL betting?

The over/under — also called the total — is a bet on the combined score of both teams. FanDuel Sportsbook sets a number (for example, 47.5 points), and you wager on whether the final total will add up to more than 47.5 points or fewer than 47.5 points. It doesn't matter which team wins; all that counts is how many points are scored in regulation and overtime combined.

What are NFL player props?

Player props are individual performance bets focused on a specific player's stats rather than the game outcome. You can bet on a player to go over or under. Common NFL props include passing yards, rushing yards, receiving yards, touchdowns, receptions, and completions. FanDuel Sportsbook offers a wide variety of player props for every game, often including alternate lines at adjusted odds.

What is a same-game parlay (SGP)?

A same-game parlay lets you bundle multiple bets from the same NFL game — such as a team to cover the spread, a quarterback to throw for over 275 yards, and a wide receiver to score a touchdown — all into one ticket. Because the outcomes are correlated, the odds are adjusted accordingly. FanDuel Sportsbook offers same-game parlays for every game on the slate.

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The above author is a FanDuel employee and is not eligible to compete in public daily fantasy contests or place sports betting wagers on FanDuel. The advice provided by the author does not necessarily represent the views of FanDuel. Taking the author's advice will not guarantee a successful outcome. You should use your own judgment when participating in daily fantasy contests or placing sports wagers.