NFL Games This Week: Predictions, Odds, Picks, Best Bets for Week 16

The Week 16 NFL lineup has several top-tier games, including a matchup between the Philadelphia Eagles and the Washington Commanders.

If you're looking for additional betting info for Week 16 in the NFL, we have you covered with odds for all the important matchups.

Chargers vs. Broncos

The Los Angeles Chargers will host the Denver Broncos on Thursday at 8:15 p.m. ET.

• Matchup: Denver Broncos at Los Angeles Chargers
• Projected Favorite: Broncos (51.32% win probability)
• Spread: Los Angeles (-2.5)
• Total: 41.5 -- Over: (-110) | Under: (-110)
• Time: 8:15 p.m. ET
• Channel: Amazon Prime Video

Bet on Los Angeles vs. Denver with FanDuel Sportsbook.

Chiefs vs. Texans

After securing a 21-7 victory against the Browns in their last tilt, the Kansas City Chiefs (13-1) will host the Houston Texans (9-5), who are coming off a 20-12 win over the Dolphins, at GEHA Field at Arrowhead Stadium. Kickoff is slated for 1 p.m. ET on Saturday, Dec. 21.

• Matchup: Houston Texans at Kansas City Chiefs
• Projected Favorite: Chiefs (65.24% win probability)
• Spread: Kansas City (-3.5)
• Total: 41.5 -- Over: (-115) | Under: (-105)
• Time: 1 p.m. ET
• Channel: NBC

Bet on Kansas City vs. Houston with FanDuel Sportsbook.

Ravens vs. Steelers

Derrick Henry, who ranks second-best in the NFL in rushing yards, will attempt to lead the charge for the Baltimore Ravens (9-5) on Dec. 21 at 4:30 p.m. ET, when they host the Pittsburgh Steelers (10-4) and their fourth-best run defense (94.4 rushing yards allowed per game).

• Matchup: Pittsburgh Steelers at Baltimore Ravens
• Projected Favorite: Ravens (69.78% win probability)
• Spread: Baltimore (-6.5)
• Total: 44.5 -- Over: (-110) | Under: (-110)
• Time: 4:30 p.m. ET
• Channel: FOX

Bet on Baltimore vs. Pittsburgh with FanDuel Sportsbook.

Matchup favorites and win projections are provided by numberFire.

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